Patents by Inventor Erxia SHI

Erxia SHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOLATED ANTIGEN-BINDING PROTEIN AND APPLICATION THEREOF
    Publication number: 20220356259
    Abstract: An isolated antigen-binding protein, having one or more of the following properties: 1) capable of binding to human and monkey-derived GITR proteins at a KD value of 7×10?12 or below, wherein the KD value is measured by BLI method; 2) capable of stimulating immune cell proliferation; 3) capable of stimulating immune cells to secrete IFN-?, wherein the secretion is measured in T cell viability assay; 4) capable of inhibiting tumor growth and/or tumor cell proliferation; 5) capable of activating GITR signaling pathway; 6) capable of inhibiting the binding of GITR to GITRL.
    Type: Application
    Filed: July 16, 2020
    Publication date: November 10, 2022
    Inventors: Xin ZHANG, Ting XU, Hui MA, Yangyang YUAN, Shanshan NING, Shilong FU, Xiaolong PAN, Liyao ZHOU, Meng ZHAO, Erxia SHI