Patents by Inventor ESBATech - a Novartis Company LLC

ESBATech - a Novartis Company LLC has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130202605
    Abstract: The present invention provides sustained-release pharmaceutical formulations for administering proteins to the eye. In particular, the invention provides formulations comprising single chain antibodies and hydrophobic polyester hexylsubstituted poly(lactic acid) (hexPLA). The invention further provides processes for the production of sustained-release pharmaceutical formulations and medical uses thereof.
    Type: Application
    Filed: February 1, 2013
    Publication date: August 8, 2013
    Applicant: ESBATECH - A NOVARTIS COMPANY LLC
    Inventor: ESBATECH - A NOVARTIS COMPANY LLC
  • Publication number: 20130165640
    Abstract: The present invention relates to an antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a particularly well suited antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.
    Type: Application
    Filed: February 12, 2013
    Publication date: June 27, 2013
    Applicant: ESBATECH - A NOVARTIS COMPANY LLC
    Inventor: ESBATECH - A NOVARTIS COMPANY LLC
  • Publication number: 20130165639
    Abstract: The present invention relates to an antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a particularly well suited antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.
    Type: Application
    Filed: February 12, 2013
    Publication date: June 27, 2013
    Applicant: ESBATECH - A NOVARTIS COMPANY LLC
    Inventor: ESBAtech - a Novartis Company LLC
  • Publication number: 20130101586
    Abstract: The invention provides antibodies that bind to multiple antigens, said antibodies having at least two antibody light chain variable domains and two antibody heavy chain variable domains, wherein each light chain variable domain is linked to a heavy chain variable domain to form a VH/VL construct, and wherein at least one of the VH domains comprises a particular amino acid at AHo position 12, 103 and/or 144, and at least one of the VL domains comprises a particular amino acid at AHo position 47 and/or 50. Nucleic acid molecules, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them, and the use of said antibodies in medicine are also disclosed.
    Type: Application
    Filed: October 19, 2012
    Publication date: April 25, 2013
    Applicant: ESBATECH - A NOVARTIS COMPANY LLC
    Inventor: ESBATech - a Novartis Company LLC