Patents by Inventor Esben Halkjaer Hansen

Esben Halkjaer Hansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTS
    Publication number: 20190144907
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosides of steviol precursors, and steviol glycoside precursors.
    Type: Application
    Filed: May 16, 2017
    Publication date: May 16, 2019
    Inventors: Iver Klavs Riishede Hansen, Veronique Douchin, Jens Houghton-Larsen, Esben Halkjaer Hansen, Angelika Semmler, Laura Occhipinti, Kim Olsson
  • COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF VANILLIN OR VANILLIN BETA-D-GLUCOSIDE
    Publication number: 20190136270
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Application
    Filed: January 9, 2019
    Publication date: May 9, 2019
    Inventors: Joergen HANSEN, Esben Halkjaer HANSEN, Honey POLUR, Joseph M. SHERIDAN, Jonathan R. HEAL, William D.O. HAMILTON
  • Production of Steviol Glycosides in Microorganisms
    Publication number: 20190078128
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: December 16, 2016
    Publication date: March 14, 2019
    Inventors: Ganesh M. KISHORE, Michael MOTION, Paula M. HICKS, Jorgen HANSEN, Jens HOUGHTON-LARSEN, Esben Halkjaer HANSEN, Michael Dalgaard MIKKELSEN, Sabina TAVARES, Charlotte BLOM
  • PRODUCTION OF GIBBERELLINS IN RECOMBINANT HOSTS
    Publication number: 20190071474
    Abstract: The invention relates to recombinant microorganisms and methods for producing gibberellin compounds and gibberellin precursors.
    Type: Application
    Filed: March 3, 2017
    Publication date: March 7, 2019
    Inventors: Esben Halkjaer Hansen, Nina Nicoline Rasmussen, Michael Naesby, Jane Dannow Dyekjaer, Simon Carlsen, Adam Matthew Takos, Nicholas Ohler
  • Compositions and methods for the biosynthesis of vanillan or vanillin beta-D-glucoside
    Patent number: 10208293
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: February 19, 2019
    Assignees: International Flavors & Fragrances Inc., Evolva SA
    Inventors: Joergen Hansen, Esben Halkjaer Hansen, Honey Polur, Joseph M. Sheridan, Jonathan R. Heal, William D. O. Hamilton
  • COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF VANILLIN OR VANILLIN BETA-D-GLUCOSIDE
    Publication number: 20180251804
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductase thereby increasing the production of vanillin or vanillin beta-D-glucoside.
    Type: Application
    Filed: May 15, 2018
    Publication date: September 6, 2018
    Applicant: International flavors & Frangrances Inc.
    Inventors: Esben Halkjaer Hansen, Swee Chuang Lim Hallwyl, Klavs Riishede Hansen
  • Compositions and methods for the biosynthesis of vanillin or vanillin beta-D glucoside
    Patent number: 10066252
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductase thereby increasing the production of vanillin or vanillin beta-D-glucoside.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: September 4, 2018
    Assignee: INTERNATIONAL FLAVORS & FRAGRANCES INC.
    Inventors: Esben Halkjaer Hansen, Swee Chuang Lim Hallwyl, Klavs Riishede Hansen
  • Recombinant host cell for the biosynthesis of vanillin or vanillin beta-D-glucoside
    Patent number: 10000782
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductase thereby increasing the production of vanillin or vanillin beta-D-glucoside.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: June 19, 2018
    Assignee: INTERNATIONAL FLAVORS & FRAGRANCES INC.
    Inventors: Esben Halkjaer Hansen, Swee Chuang Lim Hallwyl, Klavs Riishede Hansen
  • Recombinant Production of Steviol Glycosides
    Publication number: 20170321238
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: February 22, 2017
    Publication date: November 9, 2017
    Inventors: Jens Houghton-Larsen, Paula Hicks, Michael Naesby, Thomas Tange Ostergaard, Jorgen Hansen, Michael Mikkelsen Dalgaard, Esben Halkjaer Hansen, Ernesto Simon, Sabina Tavares
  • Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20170240942
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: September 9, 2015
    Publication date: August 24, 2017
    Inventors: Helene Lunde Robertson, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicole Rasmussen, Esben Halkjaer Hansen
  • Production of Steviol Glycosides in Microorganisms
    Publication number: 20170218419
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: December 16, 2016
    Publication date: August 3, 2017
    Inventors: Ganesh M. KISHORE, Michael MOTION, Paula M. HICKS, Jorgen HANSEN, Jens HOUGHTON-LARSEN, Esben Halkjaer HANSEN, Michael Dalgaard MIKKELSEN, Sabina TAVARES, Charlotte BLOM
  • Methods of Improving Production of Vanillin
    Publication number: 20170172184
    Abstract: Methods for recombinant production of vanillin and compositions containing vanillin are provided by this invention.
    Type: Application
    Filed: February 12, 2015
    Publication date: June 22, 2017
    Inventors: Neil GOLDSMITH, Esben Halkjaer HANSEN, Jean-Philippe MEYER, Federico BRIANZA
  • Production of steviol glycosides in microorganisms
    Patent number: 9562251
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: February 7, 2017
    Assignee: Evolva SA
    Inventors: Ganesh M. Kishore, Jorgen Hansen, Jens Houghton-Larsen, Esben Halkjær Hansen, Michael Dalgaard Mikkelsen, Sabina Tavares, Charlotte Blom
  • COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF VANILLIN OR VANILLIN BETA-D-GLUCOSIDE
    Publication number: 20160153016
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductase thereby increasing the production of vanillin or vanillin beta-D-glucoside.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 2, 2016
    Inventors: Esben Halkjaer Hansen, Swee Chuang Lim Hallwyl, Klavs Riishede Hansen
  • Vanillin Synthase
    Publication number: 20150267227
    Abstract: The invention relates to methods for producing vanillin and related compounds. The methods involve use of a vanillin synthase capable of catalyzing side chain cleavage of ferulic acid to form vanillin. The invention also relates to host organisms expressing such vanillin synthases useful in the methods.
    Type: Application
    Filed: November 5, 2013
    Publication date: September 24, 2015
    Inventors: Birger Lindberg Møller, Esben Halkjaer Hansen, Jørgen Hansen, Nethaji Janeshawari Gallage
  • Methods and Materials for Recombinant Production of Saffron Compounds
    Publication number: 20140248668
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a zeaxanthin cleavage dioxygenase alone or in combination with recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce compounds from saffron such as crocetin, crocetin dialdehyde, crocin, or picrocrocin.
    Type: Application
    Filed: August 7, 2012
    Publication date: September 4, 2014
    Applicant: EVOLVA SA
    Inventors: Shriram Raghavan, Jorgen Hansen, Shailendra Sonkar, Sathish Kumar, Murali Panchapagesa, Esben Halkjaer Hansen, Klavs Riishede Hansen, Kalyan Kumar
  • COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF VANILLAN OR VANILLIN BETA-D-GLUCOSIDE
    Publication number: 20140245496
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Application
    Filed: August 7, 2012
    Publication date: August 28, 2014
    Applicants: EVOLVA SA, INTERNATIONAL FLAVORS & FRAGRANCES INC.
    Inventors: Joergen Hansen, Esben Halkjaer Hansen, Honey Polur, Joseph M. Sheridan, Jonathan R. Heal, William D.O. Hamilton
  • PRODUCTION OF STEVIOL GLYCOSIDES IN MICROORGANISMS
    Publication number: 20130171328
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: June 2, 2011
    Publication date: July 4, 2013
    Inventors: Ganesh M. Kishore, Michael Motion, Paula M. Hicks, Jorgen Hansen, Jens Houghton-Larsen, Esben Halkjær Hansen, Michael Dalgaard Mikkelsen, Sabina Tavares, Charlotte Blom