Patents by Inventor Esben Peter Friis

Esben Peter Friis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210380667
    Abstract: Disclosed are protease inhibitors capable of inhibiting the protease activity of a S1 or a S8 protease at ambient pH, but where the inhibitor further has a pH dependent binding to the S1 or the S8 inhibitor meaning that a complex of a S1 and a S8 protease and the inhibitor dissociates when pH is lowered to a pH below 6.0, e.g. to a pH value in the range of 4.0 to 6.0; e.g. in the range of 4.5 to 6.0; e.g. in the range of 4.5 to 5.5; whereby the protease activity is released.
    Type: Application
    Filed: October 8, 2019
    Publication date: December 9, 2021
    Applicant: Novozymes A/S
    Inventors: Poul Erik Pedersen, Esben Peter Friis, Carsten Andersen, Peter Rahbek Oestergaard, Johan Qvist
  • Patent number: 11180745
    Abstract: The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: November 23, 2021
    Assignee: Novozymes A/S
    Inventors: Carsten Andersen, Signe E. Larsen, Esben Peter Friis, Pernille Ollendorff Micheelsen, Anders Viksoee-Nielsen, Randy Deinhammer, Xinyu Shen
  • Publication number: 20210355470
    Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: July 16, 2021
    Publication date: November 18, 2021
    Applicant: Novozymes A/S
    Inventors: Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaanger Christiansen
  • Patent number: 11174452
    Abstract: The present invention relates to compositions comprising protease variants suitable for use in cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: November 16, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Peter Kamp Hansen, Esben Peter Friis, Torben Vedel Borchert, Lars Lehmann Hylling Christensen, Jens Erik Nielsen, Maria Berggaard Silow
  • Patent number: 11091748
    Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: August 17, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaanger Christiansen
  • Publication number: 20210230516
    Abstract: The present invention relates to novel protease variants exhibiting improved stability and or improved wash performance in liquid detergent. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
    Type: Application
    Filed: April 6, 2021
    Publication date: July 29, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Miguel Duarte Guilherme Pereira Toscano, Esben Peter Friis, Rolf Thomas Lenhard, Signe Eskildsen Larsen, Astrid Munch, Bena-Marie Lue, Mikael Bauer
  • Publication number: 20210189297
    Abstract: The invention relates to subtilase variants having improved stability, compositions comprising the variants, in particular detergent compositions, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; as well as methods of producing the variants and methods for stabilizing a subtilase variant
    Type: Application
    Filed: June 24, 2019
    Publication date: June 24, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Rolf Thomas Lenhard, Lars Lehmann Hylling Christensen, Carl Mikael Bauer, Esben Peter Friis, Julie Bille Rannes
  • Patent number: 11001786
    Abstract: The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: May 11, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Miguel Duarte Guilherme Pereira Toscano, Esben Peter Friis, Bena-Marie Lue
  • Patent number: 10995304
    Abstract: The present invention relates to novel protease variants exhibiting improved stability and or improved wash performance in liquid detergent. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: May 4, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Miguel Duarte Guilherme Pereira Toscano, Esben Peter Friis, Rolf Thomas Lenhard, Signe Eskildsen Larsen, Astrid Munch, Bena-Marie Lue, Mikael Bauer
  • Publication number: 20210062172
    Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: November 10, 2020
    Publication date: March 4, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Esben Peter Friis, Leonardo De Maria, Jesper Vind, Thomas A. Poulsen, Allan Svendsen, Steffen Danielsen, Rolf T. Lenhard, Henrik Friis-Madsen, Lars K. Skov
  • Publication number: 20210009979
    Abstract: The invention relates to subtilase variants and detergent compositions comprising the variants, as well as methods of producing the variants and methods for stabilizing a subtilase variant.
    Type: Application
    Filed: March 21, 2019
    Publication date: January 14, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Esben Peter Friis, Rolf Thomas Lenhard, Lars Lehmann Hylling Christensen, Carl Mikael Bauer
  • Publication number: 20200392206
    Abstract: Based on the three-dimensional structure of albumin, the inventors have designed variant polypeptides (muteins) which have one or more cysteine residues with a free thiol group (hereinafter referred to as “thio-albumin”). The variant polypeptide may be conjugated through the sulphur atom of the cysteine residue to a conjugation partner such as a bioactive compound.
    Type: Application
    Filed: March 23, 2020
    Publication date: December 17, 2020
    Inventors: Christopher John Arthur Finnis, Joanna Mary Hay, Esben Peter Friis, Jason Cameron, Darrell Sleep
  • Patent number: 10865399
    Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: December 15, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Esben Peter Friis, Leonardo De Maria, Jesper Vind, Thomas A. Poulsen, Allan Svendsen, Steffen Danielsen, Rolf T. Lenhard, Henrik Friis-Madsen, Lars K. Skov
  • Publication number: 20200385442
    Abstract: The present invention relates to variants of a parent albumin having altered plasma half-life compared with the parent albumin. The present invention also relates to fusion polypeptides and conjugates comprising said variant albumin.
    Type: Application
    Filed: May 22, 2020
    Publication date: December 10, 2020
    Inventors: Darrell Sleep, Andrew Plumridge, Jason Cameron, Inger Sandlie, Jan Terje Andersen, Esben Peter Friis
  • Publication number: 20200347323
    Abstract: The present disclosure relates to detergent compositions comprising subtilase variants exhibiting improved stability and/or improved wash performance in liquid detergent and methods for obtaining such detergent compositions. The variants are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 5, 2020
    Applicant: Henkel AG & Co. KGaA
    Inventors: Timothy O'Connell, Susanne Tondera, Hendrik Hellmuth, Thomas Weber, Rolf Thomas Lenhard, Signe Eskildsen Larsen, Miguel Duarte Guilherme Pereira Toscano, Esben Peter Friis, Astrid Munch, Mikael Bauer, Bena-Marie Lue
  • Publication number: 20200339969
    Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: July 14, 2020
    Publication date: October 29, 2020
    Applicant: NOVOZYMES A/S
    Inventors: Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaanger Christiansen
  • Publication number: 20200308563
    Abstract: The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: June 17, 2020
    Publication date: October 1, 2020
    Applicant: Novozymes A/S
    Inventors: Carsten Andersen, Signe E. Larsen, Esben Peter Friis, Pernille Ollendorff Micheelsen, Anders Viksoee-Nielsen, Randy Deinhammer, Xinyu Shen
  • Patent number: 10760036
    Abstract: The present disclosure relates to detergent compositions comprising subtilase variants exhibiting improved stability and/or improved wash performance in liquid detergent and methods for obtaining such detergent compositions. The variants are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: September 1, 2020
    Assignee: Henkel AG & Co. KGaA
    Inventors: Timothy O'Connell, Susanne Tondera, Hendrik Hellmuth, Thomas Weber, Rolf Thomas Lenhard, Signe Eskildsen Larsen, Miguel Duarte Guilherme Pereira Toscano, Esben Peter Friis, Astrid Munch, Mikael Bauer, Bena-Marie Lue
  • Patent number: 10752890
    Abstract: The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: August 25, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Frank Winther Rasmussen, Rolf Thomas Lenhard, Miguel Duarte Guilherme Pereira Toscano, Esben Peter Friis, Signe Eskildsen Larsen, Jurgen Carsten Franz Knotzel, Mikael Bauer
  • Patent number: 10752889
    Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: August 25, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Svend Kaasgaard, Jens Oebro, Signe Eskildsen Larsen, Allan Svendsen, Annette Helle Johansen, Michael Skjoet, Carsten Andersen, Lars Beier, Esben Peter Friis, Miguel Duarte Guilherme Pereira Toscano, Mads Bjoernvad, Frank Winther Rasmussen, Liv Spaanger Christiansen