Abstract: Methods, apparatuses, and systems for monitoring health of corneal tissue are disclosed. The system includes a corneal measurement device configured to measure a first state of health indicator that is tissue thickness or volume of a region of the corneal tissue during a first period of time and a second state of health indicator that is tissue thickness or volume of the region during a second period of time after the first period of time. The system further includes a processing unit configured to receive the first and second state of health indicators from the corneal measurement device and generate a health map of the region based on the first and second state of health indicators, the health map indicative of a change between the first and second state of health indicators as measured from the first period of time to the second period of time in the region of the cornea.

Abstract: Artificial corneas suitable for surgical implantation are provided. Embodiments of artificial corneas include an optical an optical element that includes a body having an anterior side and a posterior side, an annular flange extending about the body, the anterior side including an anterior optical surface and the posterior side of the body including a posterior optical surface, and a tissue integration skirt coupled to the optical element, the tissue integration skirt being configured to promote tissue ingrowth, the tissue integration skirt being coupled to the optical element such that at least a portion of a periphery of the annular flange defined between the anterior and posterior sides of the optical element is covered by the tissue integration skirt.

Abstract: The present invention is an artificial cornea designed to restore vision in patients who are not candidates to receive a natural cornea transplant (allograft). The present device construction involves the use of a biocompatible, non-porous optic disk intimately bonded to one or more anchoring layers of porous polymeric material, and a unique sealing region which enhances sealing of the artificial cornea in the recipient's eye.