Abstract: A medical guide wire torquing device that includes an elongated body defining a longitudinal axis (A) and provided with an element for receiving the guide wire. The receiving element includes a through-going bore extending inside the elongated body and a clamping body for securing torque on the guide wire in response to application of an external force in a first position and for releasing the torque from the guide wire in a second position. The wall of the elongated body has a traversing opening, and an actuator is arranged in the traverse opening in contact with the clamping body for actuating the clamping body between the first and second positions. The torque is easy to manipulate using only one hand and can be placed lengthwise of the guide wire in alternate secured and released positions without kinking the guide wire.