Abstract: The presently-disclosed subject matter relates to adsorptive radiocontrast constructs in multiple advantageous structural embodiments, which are designed to possess dual therapeutic and diagnostic actions. A concomitant therapeutic antiplatelet, as well as vasodilatation, effects, and a diagnostic real-time continuous visualization of an artery, can be obtained via direct injection of the constructs into said artery using a suitable catheter during procedural angiography with or without percutaneous intervention.

Abstract: The presently-disclosed subject matter includes a multivalent biological construct that comprises a scaffold of anisometric dimensions, comprises a biodegradable hydrophobic core coated with a hydrophilic coat of fluidic material, and pluralities of bioactive molecules tethered to said scaffold. The multivalent biologic construct interacts simultaneously with multiple corresponding binding sites, increasing the functional affinity to induce an augmented therapeutic action in the form of stimulation, activation, competitive inhibition, consumptive inhibition or modulation of a biological system. Embodiments of the presently-disclosed subject matter include methods for preparation of the present construct as well as methods for using the present constructs to overcome cellular resistance, as thrombolytics, as competitive inhibitors, as consumptive inhibitors, as vaccines and as immunomodulators to treat a subject in need thereof.

Abstract: The presently-disclosed subject matter includes a multivalent biological construct that comprises a scaffold of anisometric dimensions, comprises a biodegradable hydrophobic core coated with a hydrophilic coat of fluidic material, and pluralities of bioactive molecules tethered to said scaffold. The multivalent biologic construct interacts simultaneously with multiple corresponding binding sites, increasing the functional affinity to induce an augmented therapeutic action in the form of stimulation, activation, competitive inhibition, consumptive inhibition or modulation of a biological system. Embodiments of the presently-disclosed subject matter include methods for preparation of the present construct as well as methods for using the present constructs to overcome cellular resistance, as thrombolytics, as competitive inhibitors, as consumptive inhibitors, as vaccines and as immunomodulators to treat a subject in need thereof.

Abstract: A surveillance and tracking device (10) comprises a nest (12) holding a secondary camera (20) and a drone (14) holding a primary camera (18). Both cameras provide the operator (16) with a real time video or photos. While the secondary camera (20) surveys the local field in which the nest (12) is installed, the drone (14) can fly during the active stage of the functionality of the device (10) to follow up certain events or persons using the primary camera (18). The drone (14) can also perform routine surveillance of targeted fields. This large scale capability of the presented device (10) enables the operator (16) to perform a flexible, sustainable and more effective surveillance process. And so; the device (10) can deal up with the massively elaborated danger diversity and security challenges of the current era.