Patents by Inventor Esmeralda Ann Garcia
Esmeralda Ann Garcia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220323318Abstract: A human oral care composition, includes safe and effective amounts of the fluoride ion and stabilized chlorine dioxide, that may take the form of a paste, gel, rinse, spray, powder, varnish or similar that reduces demineralization and promotes remineralization of teeth. The method includes the topical application of the composition to the human oral cavity (including but not limited to the teeth, gingiva, and tongue), preferably at least once daily, to enhance the anti-caries effect of fluoride by released chlorine dioxide compromising any biofilm present.Type: ApplicationFiled: May 25, 2022Publication date: October 13, 2022Applicant: Micropure, Inc.Inventors: James L. Ratcliff, Lee E. Kirsch, Jessica K. Ward Dykstra, William E. Cooley, Gary Armitage, Robert Ashley, Esmeralda Ann Garcia
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Publication number: 20220280402Abstract: Various embodiments described herein provide for a multi-component compositions and methods for its pharmaceutical and cosmetic use, comprising a combination of an aliphatic anionic compound, an oxidative compound, and a buffering system. Source of fluoride ion and other carriers are optional ingredients. The aliphatic anionic compound and the oxidative compound function together, in presence or absence of fluoride ion source, to protect the oxidative compounds from degradation prior to use and upon use, and to enhance the efficacy of the composition. In addition to achieving greater stability, combined effects of the aliphatic anionic compound, oxidative compound and source of fluoride ion achieve enhanced fluoride uptake, higher enamel protection by enhanced remineralization and reduced demineralization, increased plaque removal, reduced re-growth of plaque polymicrobial biofilm, greater amount of chlorite ion availability and effective oxidation of salivary biomolecules.Type: ApplicationFiled: May 24, 2022Publication date: September 8, 2022Applicant: Micropure, Inc.Inventors: Jaiprakash G. Shewale, William E. Cooley, James L. Ratcliff, Esmeralda Ann Garcia-Smith
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Patent number: 11433010Abstract: Described herein are single-phase compositions and methods for its pharmaceutical and cosmetic use, comprising (i) a combination of N-acyl sarcosinate, (ii) an oxidative compound, and (iii) a buffering system in amounts and embodiments effective to protect the oxidative compounds from degradation prior to use and upon use and to enhance the efficacy of the composition in removing polymicrobial biofilms, reducing the re-growth of polymicrobial biofilms that leads to plaque formation, greater availability of chlorite ion for antimicrobial and cosmetic purposes, and effective oxidation of salivary biomolecules. When these single-phase compositions are comprised of a source of fluoride ion, they also achieve enhanced enamel fluoride uptake, higher enamel protection by enhanced remineralization and reduced demineralization of teeth when compared to US Pharmacopoeia Reference Dentifrice, prior known toothpastes comprising stabilized chlorine dioxide and comparable commercial dentifrices.Type: GrantFiled: November 10, 2020Date of Patent: September 6, 2022Assignee: Micropure, Inc.Inventors: Jaiprakash G. Shewale, William E. Cooley, James L. Ratcliff, Esmeralda Ann Garcia-Smith
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Patent number: 11406577Abstract: Some embodiments described herein provide for a multi-component compositions and methods for its pharmaceutical and cosmetic use, comprising a combination of an aliphatic anionic compound, an oxidative compound, and a buffering system. Source of fluoride ion and other carriers are optional ingredients. The aliphatic anionic compound and the oxidative compound function together, in presence or absence of fluoride ion source, to protect the oxidative compounds from degradation prior to use and upon use, and to enhance the efficacy of the composition. In addition to achieving greater stability, combined effects of the aliphatic anionic compound, oxidative compound and source of fluoride ion achieve enhanced fluoride uptake, higher enamel protection by enhanced remineralization and reduced demineralization, increased plaque removal, reduced re-growth of plaque polymicrobial biofilm, greater amount of chlorite ion availability and effective oxidation of salivary biomolecules.Type: GrantFiled: September 17, 2018Date of Patent: August 9, 2022Assignee: Micropure, Inc.Inventors: Jaiprakash G. Shewale, William E. Cooley, James L. Ratcliff, Esmeralda Ann Garcia-Smith
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Publication number: 20210069073Abstract: Described herein are single-phase compositions and methods for its pharmaceutical and cosmetic use, comprising (i) a combination of N-acyl sarcosinate, (ii) an oxidative compound, and (iii) a buffering system in amounts and embodiments effective to protect the oxidative compounds from degradation prior to use and upon use and to enhance the efficacy of the composition in removing polymicrobial biofilms, reducing the re-growth of polymicrobial biofilms that leads to plaque formation, greater availability of chlorite ion for antimicrobial and cosmetic purposes, and effective oxidation of salivary biomolecules. When these single-phase compositions are comprised of a source of fluoride ion, they also achieve enhanced enamel fluoride uptake, higher enamel protection by enhanced remineralization and reduced demineralization of teeth when compared to US Pharmacopoeia Reference Dentifrice, prior known toothpastes comprising stabilized chlorine dioxide and comparable commercial dentifrices.Type: ApplicationFiled: November 10, 2020Publication date: March 11, 2021Applicant: Micropure, Inc.Inventors: Jaiprakash G. Shewale, William E. Cooley, James L. Ratcliff, Esmeralda Ann Garcia-Smith
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Publication number: 20190070085Abstract: Some embodiments described herein provide for a multi-component compositions and methods for its pharmaceutical and cosmetic use, comprising a combination of an aliphatic anionic compound, an oxidative compound, and a buffering system. Source of fluoride ion and other carriers are optional ingredients. The aliphatic anionic compound and the oxidative compound function together, in presence or absence of fluoride ion source, to protect the oxidative compounds from degradation prior to use and upon use, and to enhance the efficacy of the composition. In addition to achieving greater stability, combined effects of the aliphatic anionic compound, oxidative compound and source of fluoride ion achieve enhanced fluoride uptake, higher enamel protection by enhanced remineralization and reduced demineralization, increased plaque removal, reduced re-growth of plaque polymicrobial biofilm, greater amount of chlorite ion availability and effective oxidation of salivary biomolecules.Type: ApplicationFiled: September 17, 2018Publication date: March 7, 2019Inventors: Jaiprakash G. Shewale, William E. Cooley, James L. Ratcliff, Esmeralda Ann Garcia-Smith
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Publication number: 20140178499Abstract: A composition for preventing and treating all forms of osteonecrosis of the jaw are disclosed. The composition is comprised of 0.005%-2.0% weight/volume (w/v) chlorine dioxide source, such as sodium chlorite, chlorite ion, stabilized chlorine dioxide or similar and may take the form of a paste, gel, rinse, spray, powder, varnish or similar. The prevention and treatment includes the application of the composition in the oral cavity and other body areas affected by osteonecrosis of the jaw.Type: ApplicationFiled: February 27, 2014Publication date: June 26, 2014Applicant: MICROPURE, INC.Inventors: James L. Ratcliff, Michael Z. Marder, Robert W. Marder, Jessica K. Ward Dykstra, Elena J. Young, Esmeralda Ann Garcia
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Publication number: 20140112875Abstract: A human oral care composition, includes safe and effective amounts of the fluoride ion and stabilized chlorine dioxide, that may take the form of a paste, gel, rinse, spray, powder, varnish or similar that reduces demineralization and promotes remineralization of teeth. The method includes the topical application of the composition to the human oral cavity (including but not limited to the teeth, gingiva, and tongue), preferably at least once daily, to enhance the anti-caries effect of fluoride by released chlorine dioxido compromising any biofilm present.Type: ApplicationFiled: December 31, 2013Publication date: April 24, 2014Applicant: MICROPURE, INC.Inventors: James L. Ratcliff, Lee E. Kirsch, Jessica K. Ward Dykstra, William E. Cooley, Gary Armitage, Robert Ashley, Esmeralda Ann Garcia
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Patent number: 8697141Abstract: A method and composition for preventing and treating all forms of osteonecrosis of the jaw are disclosed. The composition is comprised of 0.005%-2.0% weight/volume (w/v) chlorine dioxide source, such as sodium chlorite, chlorite ion, stabilized chlorine dioxide or similar and may take the form of a paste, gel, rinse, spray, powder, varnish or similar. The method for treatment and prevention includes the application of the composition in the oral cavity and other body areas affected by osteonecrosis of the jaw.Type: GrantFiled: August 25, 2009Date of Patent: April 15, 2014Assignee: Micropure, Inc.Inventors: James L. Ratcliff, Michael Z. Marder, Robert W. Marder, Jessica Ward Dykstra, Elena J. Young, Esmeralda Ann Garcia
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Publication number: 20120164084Abstract: A flavored oral care composition and method of making same for preventing and/or treating bacterial, fungal or inflammatory diseases and conditions of the oral cavity may be in the form of a rinse, spray, or the like, and free of glycerin and free of castor oil and castor oil derivatives, incorporates a chlorine dioxide source, a phosphate buffer, a flavoring system containing a polyoxyethylene sorbitan ester (emulsifier/suspender) and flavoring agent, a sweetener and water. With the addition of a fluoride ion source, the composition may be used as an anticaries agent.Type: ApplicationFiled: May 25, 2011Publication date: June 28, 2012Applicant: MICROPURE, INC.Inventors: James L. Ratcliff, Karen Black, William E. Cooley, Esmeralda Ann Garcia
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Publication number: 20110318282Abstract: A human oral care composition, includes safe and effective amounts of the fluoride ion and stabilized chlorine dioxide, that may take the form of a paste, gel, rinse, spray, powder, varnish or similar that reduces demineralization and promotes remineralization of teeth. The method includes the topical application of the composition to the human oral cavity (including but not limited to the teeth, gingiva, and tongue), preferably at least once daily, to enhance the anti-caries effect of fluoride by released chlorine dioxido compromising any biofilm present.Type: ApplicationFiled: December 22, 2009Publication date: December 29, 2011Applicant: MICROPURE, INC.Inventors: James L. Ratcliff, Lee E. Kirsch, Jessica K. Ward Dykstra, William E. Cooley, Gary Armitage, Robert Ashley, Esmeralda Ann Garcia
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Publication number: 20100074970Abstract: A method and composition for preventing and treating all forms of osteonecrosis of the jaw are disclosed. The composition is comprised of 0.005%-2.0% weight/volume (w/v) chlorine dioxide source, such as sodium chlorite, chlorite ion, stabilized chlorine dioxide or similar and may take the form of a paste, gel, rinse, spray, powder, varnish or similar. The method for treatment and prevention includes the application of the composition in the oral cavity and other body areas affected by osteonecrosis of the jaw.Type: ApplicationFiled: August 25, 2009Publication date: March 25, 2010Applicant: Micropure, Inc.Inventors: James L. Ratcliff, Michael Z. Marder, Robert W. Marder, Jessica Ward Dykstra, Elena J. Young, Esmeralda Ann Garcia