Patents by Inventor Esmira Naftali

Esmira Naftali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230190863
    Abstract: The present invention provides pharmaceutical compositions of a hydroxyl halide of a peptide and methods of use of these compositions in treating viral infections caused by coronavirus and influenza viruses.
    Type: Application
    Filed: April 21, 2021
    Publication date: June 22, 2023
    Applicant: CODE PHARMA B.V.
    Inventors: Zyon AYNI, Eynat FINKELSHTEIN, Esmira NAFTALI
  • Publication number: 20220233652
    Abstract: The present invention provides pharmaceutical compositions of an integration-promoting peptide and hydroxyl halide salts of said peptide. The pharmaceutical compositions of the present invention are stable and maintain the peptide soluble upon administration. Methods of treating viral infection and cancer with the peptide salts and compositions thereof are also provided.
    Type: Application
    Filed: August 22, 2019
    Publication date: July 28, 2022
    Inventors: Esmira Naftali, Zyon Ayni
  • Publication number: 20130023485
    Abstract: The subject invention provides a pharmaceutical composition comprising: an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of a pharmaceutically acceptable salt of a) a peptide comprising at least 12 and at most 30 consecutive amino acids, b) a peptide comprising consecutive amino acids having the sequence shown by any of SEQ ID NOS. 8-17, c) a peptide comprising consecutive amino acids having a sequence of any of a) and b), or at least two sequences in (a), or d) a peptide comprising consecutive amino acids having a sequence comprising at least two identical sequences included in (a); and a solubility enhancer; and wherein the composition has a pH between 4 and 9, and a method of alleviating symptoms of SLE in a human by administering an effective amount of the composition.
    Type: Application
    Filed: April 23, 2012
    Publication date: January 24, 2013
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Publication number: 20090169559
    Abstract: The subject invention provides a pharmaceutical composition comprising: an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of the composition of a pharmaceutically acceptable salt of a) a peptide comprising at least 12 and at most 30 consecutive amino acids having a sequence corresponding to (i) a sequence of amino acids found within a complementarity-determining region (CDR) of a heavy or a light chain of a human monoclonal anti-DNA 16/6 Id antibody, or (ii) a sequence of amino acids found within a complementarity-determining region (CDR) of a heavy or a light chain of a pathogenic anti-DNA monoclonal antibody that induces a systemic lupus erythematosus (SLE)-like disease response in mice, or b) a peptide comprising consecutive amino acids having the sequence shown by any of SEQ ID NOS.
    Type: Application
    Filed: November 10, 2008
    Publication date: July 2, 2009
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Publication number: 20080287366
    Abstract: The subject invention provides a pharmaceutical composition comprising an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of the composition of a pharmaceutically acceptable salt of a peptide having the structural formula NH2-Gly Tyr Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Glu Glu Trp Ile Gly-COOH; and a substituted ?-cyclodextrin in an amount effective to dissolve the peptide in the aqueous carrier, wherein the composition has a pH between 4 and 9, a process for preparation, and a method of alleviating symptoms of systemic lupus erythematosus (SLE) in a human subject comprising administering to the human subject the pharmaceutical composition.
    Type: Application
    Filed: November 12, 2007
    Publication date: November 20, 2008
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Patent number: 7294687
    Abstract: The subject invention provides a pharmaceutical composition comprising an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of the composition of a pharmaceutically acceptable salt of a peptide having the structural formula NH2-Gly Tyr Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Glu Glu Trp Ile Gly-COOH; and a substituted ?-cyclodextrin in an amount effective to dissolve the peptide in the aqueous carrier, wherein the composition has a pH between 4 and 9, a process for preparation, and a method of alleviating symptoms of systemic lupus erythematosus (SLE) in a human subject comprising administering to the human subject the pharmaceutical composition.
    Type: Grant
    Filed: January 14, 2004
    Date of Patent: November 13, 2007
    Assignee: TEVA Pharmaceutical Industries, Ltd.
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Publication number: 20050008634
    Abstract: The subject invention provides a pharmaceutical composition comprising: an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of the composition of a pharmaceutically acceptable salt of a) a peptide comprising at least 12 and at most 30 consecutive amino acids having a sequence corresponding to (i) a sequence of amino acids found within a complementarity-determining region (CDR) of a heavy or a light chain of a human monoclonal anti-DNA 16/6 Id antibody, or (ii) a sequence of amino acids found within a complementarity-determining region (CDR) of a heavy or a light chain of a pathogenic anti-DNA monoclonal antibody that induces a systemic lupus erythematosus (SLE)-like disease response in mice, or b) a peptide comprising consecutive amino acids having the sequence shown by any of SEQ ID NOS.
    Type: Application
    Filed: January 14, 2004
    Publication date: January 13, 2005
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger
  • Publication number: 20040180059
    Abstract: The subject invention provides a pharmaceutical composition comprising an aqueous carrier; from 0.
    Type: Application
    Filed: January 14, 2004
    Publication date: September 16, 2004
    Inventors: Sharon Cohen-Vered, Esmira Naftali, Vera Weinstein, Adrian Gilbert, Ety Klinger