Patents by Inventor Esperanza Nieves

Esperanza Nieves has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutically active compounds and methods of use thereof
    Publication number: 20070155703
    Abstract: The invention includes pharmaceutically active compounds and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for treatment or prophylaxis of undesired thrombosis.
    Type: Application
    Filed: February 15, 2007
    Publication date: July 5, 2007
    Applicant: Tanox, Inc.
    Inventors: Jin-An Jiao, Lawrence Luepschen, Esperanza Nieves, Hing Wong, Dean Taylor
  • Pharmaceutically active compounds and methods of use thereof
    Patent number: 7199113
    Abstract: The invention includes pharmaceutically active compounds and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for treatment or prophylaxis of undesired thrombosis.
    Type: Grant
    Filed: December 6, 2004
    Date of Patent: April 3, 2007
    Inventors: Jin-An Jiao, Lawrence K. Luepschen, Esperanza Nieves, Hing C. Wong, Dean P. Taylor
  • Use of anti-tissue factor antibodies for treating thromboses
    Publication number: 20060235209
    Abstract: Disclosed is a method for preventing or treating thrombosis in a mammal such as a primate and particularly a human patient. A preferred method includes administering to the mammal a therapeutically effective amount of at least one humanized antibody, chimeric antibody, or fragment thereof that binds specifically to human tissue factor (TF). Additional methods and kits are provided.
    Type: Application
    Filed: December 4, 2002
    Publication date: October 19, 2006
    Inventors: Jin-An Jiao, Hing Wong, Esperanza Nieves, Luis Mosquera
  • Antibodies for inhibiting blood coagulation and methods of use thereof
    Publication number: 20060039901
    Abstract: The invention includes antibodies that provide superior anti-coagulant activity by binding native human TF with high affinity and specificity. Antibodies of the invention can effectively inhibit blood coagulation in vivo. Antibodies of the invention can bind native human TF, either alone or present in a TF:FVIIa complex, effectively preventing factor X or FIX binding to TF or that complex, and thereby reducing blood coagulation. Preferred antibodies of the invention specifically bind a conformational epitope predominant to native human TF, which epitope provides an unexpectedly strong antibody binding site. Also provided are humanized antibodies and fragments thereof that bind to the TF.
    Type: Application
    Filed: May 5, 2005
    Publication date: February 23, 2006
    Applicant: Tanox, Inc.
    Inventors: Jin-An Jiao, Hing Wong, Esperanza Nieves, Lawrence Luepschen
  • Antibodies for inhibiting blood coagulation and methods of use thereof
    Publication number: 20050271664
    Abstract: The invention includes antibodies that provide superior anti-coagulant activity by binding native human TF with high affinity and specificity. Antibodies of the invention can effectively inhibit blood coagulation in vivo. Antibodies of the invention can bind native human TF, either alone or present in a TF:VIIa complex, effectively preventing factor X binding to TF or that complex, and thereby reducing blood coagulation. Preferred antibodies of the invention specifically bind a conformational epitope predominant to native human TF, which epitope provides an unexpectedly strong antibody binding site.
    Type: Application
    Filed: March 22, 2005
    Publication date: December 8, 2005
    Applicant: Tanox, Inc.
    Inventors: Hing Wong, Jin-An Jiao, Esperanza Nieves, Lawrence Luepschen
  • Pharmaceutically active compounds and methods of use thereof
    Publication number: 20050245488
    Abstract: The invention includes pharmaceutically active compounds and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for treatment or prophylaxis of undesired thrombosis.
    Type: Application
    Filed: December 6, 2004
    Publication date: November 3, 2005
    Applicant: Sunol Molecular
    Inventors: Jian-An Jiao, Lawrence Luepschen, Esperanza Nieves, Hing Wong, Dean Taylor
  • Pharmaceutically active compounds and methods of use thereof
    Patent number: 6828312
    Abstract: The invention includes pharmaceutically active compounds and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for treatment or prophylaxis of undesired thrombosis.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: December 7, 2004
    Assignee: Sunol Molecular Corporation
    Inventors: Jin-An Jiao, Lawrence K. Luepschen, Esperanza Nieves, Hing C. Wong, Dean P. Taylor