Abstract: A composition, which includes ingredients capable of enhancing the immunogenic effect of a vaccine, includes an aluminium salt and at least one ginsenoside, such as a tri-terpenoid glycoside, preferably a tri-terpenoid glycoside of the structure of Rb1. In one particular embodiment, the aluminium salt is Al(OH)3. A kit for use as adjuvant or co-adjuvant of an immunogenic composition includes the composition. The use of such a tri-terpenoid glycoside in the manufacture of a pharmaceutical preparation enhanced the immunogenic effect of a vaccine. A pharmaceutical preparation includes the composition and an aluminium salt, such as Al(OH)3 and a pharmaceutically acceptable carrier.

Abstract: The present invention relates to a composition, which includes ingredients capable of enhancing the immunogenic effect of a vaccine, which composition comprises an aluminium salt and at least one ginsenoside, such as a tri-terpenoid glycoside, preferably a tri-terpenoid glycoside that comprises the structure of Rb1. In one particular embodiment, said aluminium salt is Al(OH)3. In a further aspect, the present invention relates to a kit comprising the composition, for use as adjuvant or co-adjuvant of an immunogenic composition as well as to the use of such a tri-terpenoid glycoside in the manufacture of a pharmaceutical preparation for enhancing the immunogenic effect of a vaccine. In addition, the invention also relates to a pharmaceutical preparation manufactured by the present use, which pharmaceutical preparation further comprises an aluminium salt, such as Al(OH)3 and a pharmaceutically acceptable carrier.