Patents by Inventor Ester BORRONI

Ester BORRONI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vector with an endothelial-specific promoter for treating factor V, VII, VIII, or IX deficiency
    Patent number: 12460225
    Abstract: Sequences derived from Stabilin-2 promoter are used as a promoter to drive the expression of a gene specifically into endothelial cells, preferably said gene is a therapeutic gene, such as FVIII or any gene involved in the coagulation cascade. Moreover, the use of these sequences is for medical purposes, in particular, to treat a genetic disease, such as hemophilia, preferably by gene and/or cellular therapy.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: November 4, 2025
    Assignee: UNIVERSITA' DEL PIEMONTE ORIENTALE
    Inventors: Antonia Follenzi, Simone Merlin, Ester Borroni, Chiara Borsotti, Valentina Bruscaggin, Silvia Zucchelli
  • ENDOTHELIAL-SPECIFIC PROMOTER SEQUENCES AND USES THEREOF
    Publication number: 20200165631
    Abstract: Sequences derived from Stabilin-2 promoter are used as a promoter to drive the expression of a gene specifically into endothelial cells, preferably said gene is a therapeutic gene, such as FVIII or any gene involved in the coagulation cascade. Moreover, the use of these sequences is for medical purposes, in particular, to treat a genetic disease, such as hemophilia, preferably by gene and/or cellular therapy.
    Type: Application
    Filed: July 26, 2018
    Publication date: May 28, 2020
    Applicant: UNIVERSITA' DEL PIEMONTE ORIENTALE
    Inventors: Antonia FOLLENZI, Simone MERLIN, Ester BORRONI, Chiara BORSOTTI, Valentina BRUSCAGGIN, Silvia ZUCCHELLI