Patents by Inventor Ester Fernandez Gimeno

Ester Fernandez Gimeno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND REAGENTS FOR EFFICIENT AND TARGETED GENE TRANSFER TO MONOCYTES AND MACROPHAGES
    Publication number: 20150174257
    Abstract: The present invention provides a biosafe and useful vector to transfer genetic material to CD14+ mononuclear cells (monocytes and monocyte-derived macrophages) in an efficient and specific manner. The embodiment of the invention makes use of the chimeric human adenovirus vectors 5 carrying the short fiber of enterotropic Ad40 to transfer genetic material to the target CD14+ mononuclear cells.
    Type: Application
    Filed: March 3, 2015
    Publication date: June 25, 2015
    Inventors: Miquel Angel GASSULL DURO, Adolfo RIO FERNANDEZ, Ester FERNANDEZ GIMENO, Miguel CHILLON RODRIGUEZ
  • DERIVATIVES OF SMALL INTERFERING RNAS AND USE THEREOF
    Publication number: 20130274317
    Abstract: The present invention relates to a small interfering RNA (siRNA) being 2?-O-methyl modified and there being attached thereto by a phosphodiester bond a position 3?, wherein group R in position 3?, wherein R is selected from among: a C1-C6 alkyl substituted with at least one —OH group; a C4-C6 cycloalkyl substituted with at least one —OH group; a C4-C6 heterocycloalkyl; a heteroalkyl chain having between 2 and 7 atoms, wherein at least one is an oxygen atom or a sulphur atom, the chain preferably being substituted with at least one —OH group; and a heteroaryl the ring whereof being formed of between 3 and 6 atoms and at least one of said atoms is an oxygen atom. The present invention furthermore refers to the use of said siRNA for the treatment of inflammatory diseases, preferably inflammatory bowel disease.
    Type: Application
    Filed: October 26, 2011
    Publication date: October 17, 2013
    Inventors: Sandra Milena Ocampo, Ramón Eritja Casadellá, Carolina Romero Prada, Juan Burgueño Banús, Ester Fernández Gimeno, Jose Carlos Perales
  • METHODS AND REAGENTS FOR EFFICIENT AND TARGETED GENE TRANSFER TO MONOCYTES AND MACROPHAGES
    Publication number: 20120045389
    Abstract: The present invention provides a biosafe and useful vector to transfer genetic material to CD14+ mononuclear cells (monocytes and monocyte-derived macrophages) in an efficient and specific manner. The embodiment of the invention makes use of the chimeric human adenovirus vectors 5 carrying the short fiber of enterotropic Ad40 to transfer genetic material to the target CD14+ mononuclear cells.
    Type: Application
    Filed: April 28, 2010
    Publication date: February 23, 2012
    Applicants: UNIVERSITAT AUTÒNOMA DE BARCELONA, FUNDACIÓ PRIVADA INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANCATS, FUNDACIÓ INSTITUT D'INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL, GRIFOLS, S.A.
    Inventors: Miquel Àngel Gassull Duro, Adolfo Rio Fernandez, Ester Fernandez Gimeno, Miguel Chillón Rodriguez