Patents by Inventor Esther De Graaff

Esther De Graaff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for anti-TR antibodies
    Patent number: 9097716
    Abstract: The present invention relates to a method for determining the presence of anti-Tr antibodies in a subject comprising the steps of obtaining a sample from said subject testing the presence of said antibodies in said sample by addition of DNER protein or an antigenic part thereof and checking whether said DNER protein is bound by any antibodies in said sample Such an assay is useful for the diagnosis of paraneoplastic cerebellar degeneration that is associated with Hodgkin lymphoma, or, more generally, to type patients suffering from cerebellar ataxia. Also comprised in the invention is a kit for performing such an assay.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: August 4, 2015
    Assignee: Erasmus University Medical Center
    Inventors: Petrus Abraham Elisa Sillevis Smitt, Esther De Graaff
  • ASSAY FOR ANTI-TR ANTIBODIES
    Publication number: 20150050668
    Abstract: The present invention relates to a method for determining the presence of anti-Tr antibodies in a subject comprising the steps of obtaining a sample from said subject testing the presence of said antibodies in said sample by addition of DNER protein or an antigenic part thereof and checking whether said DNER protein is bound by any antibodies in said sample Such an assay is useful for the diagnosis of paraneoplastic cerebellar degeneration that is associated with Hodgkin lymphoma, or, more generally, to type patients suffering from cerebellar ataxia. Also comprised in the invention is a kit for performing such an assay.
    Type: Application
    Filed: March 1, 2012
    Publication date: February 19, 2015
    Applicant: Erasmus University Medical Center Rotterdam
    Inventors: Petrus Abraham Elisa Sillevis Smitt, Esther De Graaff