Patents by Inventor Esther Race

Esther Race has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070269797
    Abstract: The present invention relates to a method for analyzing the phenotypic characteristics shown by certain virus strains, particularly human immunodeficiency viruses, involving the construction of a recombinant virus obtained by homologous recombination. The present invention also relates a kit comprising the primers, vectors, cell hosts, products and reagents required to carry out PCR amplification, and the products and reagents used to detect a marker, for the implementation of the method according to the invention.
    Type: Application
    Filed: May 12, 2003
    Publication date: November 22, 2007
    Inventors: Francois Clavel, Fabrizio Mammano, Esther Race, Elisabeth Dam, Veronique Obry, Virginie Trouplin
  • Publication number: 20040101828
    Abstract: The present invention relates to a method for analyzing the phenotypic characteristics shown by certain virus strains, particularly human immunodeficiency viruses, involving the construction of a recombinant virus obtained by homologous recombination.
    Type: Application
    Filed: May 12, 2003
    Publication date: May 27, 2004
    Applicant: BIOALLIANCE PHARMA INSERM
    Inventors: Francois Clavel, Fabrizio Mammano, Esther Race, Elisabeth Dam, Veronique Obry, Virginie Trouplin
  • Publication number: 20040053219
    Abstract: The present invention relates to a method for analysing the phenotypic characteristics shown by certain virus strains, particularly human immunodeficiency viruses, involving the construction of a recombinant virus obtained by homologous recombination.
    Type: Application
    Filed: May 13, 2003
    Publication date: March 18, 2004
    Applicants: Bioalliance Pharma (S.A.), Inserm
    Inventors: Francois Clavel, Esther Race, Veronique Obry, Fabrizio Mammano, Elisabeth Dam, Virginie Trouplin
  • Publication number: 20030207294
    Abstract: The present invention relates to a method for analysing the phenotypic characteristics shown by certain virus strains, particularly human immunodeficiency viruses, involving the construction of a recombinant virus obtained by homologous recombination.
    Type: Application
    Filed: October 4, 2002
    Publication date: November 6, 2003
    Applicant: Bioalliance Pharma (S.A)
    Inventors: Francois Clavel, Esther Race, Veronique Obry, Fabrizio Mammano, Elisabeth Dam, Virginie Trouplin
  • Patent number: 6558923
    Abstract: The invention provides an in vitro single cycle, recombinant virus assay (RVA) for determining inhibition of HIV replication by a protease inhibitor. The assay comprises transfecting a human epithelial cell line with amplified HIV protease sequences of an HIV virus; an HIV envelope defective molecular clone having a complete deletion of its protease coding sequence as well as two separate deletions in its env gene and a deletion of part of its gag gene; and a plasmid containing HIV envelope coding sequence under the control of a promoter for phenotypic complementation of the envelope defective molecular clone. The transfected cells are cultured in the presence of a protease inhibitor to produce a testable stock of infectious particles that can be used to infect indicator cells containing an indicator gene without amplification of the infectious particles prior to infecting the indicator cells. Accumulation of indicator gene product is a measure of inhibition of HIV replication by the protease inhibitor.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: May 6, 2003
    Assignee: Institut Pasteur
    Inventors: Sylvie Paulous, Pierre Charneau, Véronique Zennou, François Clavel, Esther Race, Elisabeth Dam, Véronique Obry
  • Publication number: 20020123036
    Abstract: The present invention relates to a method for analyzing the phenotypic characteristics shown by certain virus strains, particularly human immnunodeficiency viruses, involving the construction of a recombinant virus obtained by homologous recombination.
    Type: Application
    Filed: March 27, 2001
    Publication date: September 5, 2002
    Inventors: Francois Clavel, Esther Race, Veronique Obry, Fabrizio Mammano, Elisabeth Dam, Virginie Trouplin
  • Publication number: 20020119444
    Abstract: The invention provides an in vitro single cycle, recombinant virus assay (RVA) for determining inhibition of HIV replication by a protease inhibitor. The assay comprises transfecting a human epithelial cell line with amplified HIV protease sequences of an HIV virus; an HIV envelope defective molecular clone having a complete deletion of its protease coding sequence as well as two separate deletions in its env gene and a deletion of part of its gag gene; and a plasmid containing HIV envelope coding sequence under the control of a promoter for phenotypic complementation of the envelope defective molecular clone. The transfected cells are cultured in the presence of a protease inhibitor to produce a testable stock of infectious particles that can be used to infect indicator cells containing an indicator gene without amplification of the infectious particles prior to infecting the indicator cells. Accumulation of indicator gene product is a measure of inhibition of HIV replication by the protease inhibitor.
    Type: Application
    Filed: November 16, 2001
    Publication date: August 29, 2002
    Inventors: Sylvie Paulous, Pierre Charneau, Veronique Zennou, Francois Clavel, Esther Race, Elizabeth Dam, Veronique Obry