Patents by Inventor Esther Shohami

Esther Shohami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor necrosis factor .alpha. (TNF-.alpha.) inhibiting pharmaceuticals
    Patent number: 5932610
    Abstract: Pharmaceutical compositions are described for preventing TNF toxicity, comprising as active ingredient the stereospecific (+) enantiomer, having 3S, 4S) configuration of .DELTA..sup.6 tetrahydrocannabinol type compounds. The compositions are particularly effective in alleviating and even preventing neurotoxicity due to elevated levels of TNF, including septic shock, cachexia and trauma. They are also effective in the treatment of certain chronic degenerative diseases characterized by TNF production, including autoimmune diseases.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: August 3, 1999
    Assignee: Yissum Research Development Co. of The Hebrew University
    Inventors: Esther Shohami, Ruth Gallily, Raphael Mechoulam