Patents by Inventor Eswaramoorthy Muthusamy

Eswaramoorthy Muthusamy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A NANOFORMULATION FOR GLIOMA TREATMENT AND PROCESS FOR ITS PREPARATION THEREOF
    Publication number: 20240122912
    Abstract: The present invention describes the development of a novel, tumor epithelial cell and tumor-associated macrophage (TAM)-targeting, blood brain barrier (BBB) crossing glucose-based nanospheres (CSP). More specifically, the present invention discloses a nanoformulation and/or a composition having anticancer activity comprising of carbon nanosphere (CSP) and a sigma receptor targeting ligand (H8) in the ratio of 1:0.08 to 1:0.2, a complex prepared thereof, a process for preparation thereof and a kit for delivery of the drug molecule or the formulation or the composition to tumor site.
    Type: Application
    Filed: March 29, 2022
    Publication date: April 18, 2024
    Inventors: Madhan Mohan Chandra Sekhar JAGGARAPU, Eswaramoorthy MUTHUSAMY, Tapas Kamar KUNDU, Rajkumar BANERJEE
  • Intrinsically fluorescent carbon nanospheres and a process thereof
    Patent number: 9034387
    Abstract: The present invention provides solution to the problem involved in delivery of active molecules to nucleus. More particularly, the invention provides intrinsically fluorescent and inherently surface functionalized carbon nanospheres which are non-toxic. Also, these carbon nanospheres [CSP] were adsorbed with CTPB [CSP-CTPB] and the adsorbed CSP-CTPB are permeable to cells with nuclear targeting ability. In addition, the present invention provides a composition, a process to prepare the composition comprising CSP with adsorbed active/therapeutic molecules. Further, the instant invention provides a method for delivering active molecules inside a cell nucleus.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: May 19, 2015
    Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
    Inventors: Tapas Kumar Kundu, Eswaramoorthy Muthusamy, Sr., Ruthrotha Selvi Bharatha Vikru, Dinesh Jagadeesan
  • Template free and polymer free metal, nanosponge and a process thereof
    Patent number: 8404280
    Abstract: The present invention provides solution to the problem involved in preparation of metal nanosponges using templates and polymers. The instant invention is successful in providing a simple, template free single step process for the preparation of metal nanosponges having porous low density and high surface area. These metal nanosponges were found to be good self-supported substrates for surface-enhanced Raman spectroscopy (SERS) and have shown significant anti-bacterial activity.
    Type: Grant
    Filed: May 4, 2009
    Date of Patent: March 26, 2013
    Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
    Inventors: Eswaramoorthy Muthusamy, Sai Krishna Katla
  • Template Free and Polymer Free Metal, Nanosponge and a Process Thereof
    Publication number: 20110014300
    Abstract: The present invention provides solution to the problem involved in preparation of metal nanosponges using templates and polymers. The instant invention is successful in providing a simple, template free single step process for the preparation of metal nanosponges having porous low density and high surface area. These metal nanosponges were found to be good self-supported substrates for surface-enhanced Raman spectroscopy (SERS) and have shown significant anti-bacterial activity.
    Type: Application
    Filed: May 4, 2009
    Publication date: January 20, 2011
    Applicant: JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTFIC RES
    Inventors: Eswaramoorthy Muthusamy, Saikrishana Katla
  • INTRINSCIALLY FLUORESCENT CARBON NANOSPHERES AND A PROCESS THEREOF
    Publication number: 20100215760
    Abstract: The present invention provides solution to the problem involved in delivery of active molecules to nucleus. More particularly, the invention provides intrinsically fluorescent and inherently surface functionalized carbon nanospheres which are non-toxic. Also, these carbon nanospheres [CSP] were adsorbed with CTPB [CSP-CTPB] and the adsorbed CSP-CTPB are permeable to cells with nuclear targeting ability. In addition, the present invention provides a composition, a process to prepare the composition comprising CSP with adsorbed active/therapeutic molecules. Further, the instant invention provides a method for delivering active molecules inside a cell nucleus.
    Type: Application
    Filed: September 30, 2008
    Publication date: August 26, 2010
    Applicant: JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH
    Inventors: Tapas Kumar Kundu, Eswaramoorthy Muthusamy, Ruthrotha Selvi Bharatha Vikru, Dinesh Jagadeesan