Abstract: A composition containing Zolmitriptan in the form of oral disintegrating tablet for the acute treatment of migraines is disclosed. The said composition comprises (a) Zolmitriptan, a salt or solvate or polymorph thereof as active ingredient, (b) mannitol, and (c) calcium silicate, and (d) optionally, one or more polysaccharides along with one or more pharmaceutically acceptable excipients.

Abstract: This invention describes the use of pharmaceutical compositions, which comprise three components of which at least one is a slow release therapeutic agent. Such useful compositions are applicable for the treatment of humans suffering from diabetic, hypertensive, cardiovascular, hyperlipidemic conditions and their associated disorders thereof. Combination therapy has the advantages of better patient compliance; better therapeutic efficacy coupled with a reduction in the dose for some of the individual therapeutic agent(s) in the combination.