Patents by Inventor Eszter Toth
Eszter Toth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240060095Abstract: The present invention relates to a process for producing alcohols, according to which a sugary fluid (2) is introduced into a reaction section (1) comprising a support (4) on which microorganisms are immobilized, in order to produce, by fermentation, an alcohol-enriched must (3) under the action of said microorganisms, characterized in that the process is carried out continuously, and such that a portion of spent support (41) is periodically replaced by a portion of new and/or regenerated support (46).Type: ApplicationFiled: December 2, 2021Publication date: February 22, 2024Applicant: IFP Energies nouvellesInventors: Jean-Christophe GABELLE, Eszter TOTH, Nicolas LOPES FERREIRA, Helene VELLY, Amandine GINET, Severine ARTERO
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Publication number: 20230265464Abstract: The present invention relates to a process for producing alcohols comprising: a. an IBE-type fermentation step in at least one bioreactor (R1) in the presence of a natural strain microorganism, and fed at least with an aqueous solution (1) of C5 and/or C6 sugars and a recycled acetone stream (3), in order to produce fermentation gases and a fermentation broth containing fermentation products; b. a step of recovering the fermentation products, in order to obtain a stream of fermentation products (2); c. a step of treating the stream of fermentation products comprising an acetone separation section in order to produce at least an acetone effluent (3) and an aqueous alcohol effluent (4); d. a step for recycling at least a fraction of the acetone effluent (3) from step c) to step a).Type: ApplicationFiled: June 17, 2021Publication date: August 24, 2023Applicant: IFP Energies NouvellesInventors: Marcel ROPARS, Nicolas LOPES FERREIRA, Sandra MENIR, Helena GONZALEZ PENAS, Eszter TOTH, Vincent COUPARD
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Publication number: 20230031899Abstract: Some aspects of the present disclosure provide compositions, methods, and kits for improving the specificity and/or targetable sequence space of endonucleases programmable by RNA such as Cas9. Also provided herein are variants of Cas9 that have been engineered to have improved specificity for cleaving nucleic acid targets. Also provided herein are variants of Cas9 with increased fidelity that have been engineered to became compatible with 5? extended sgRNAs such as 21G-sgRNAs. Such Cas9 variants are useful in clinical and research settings involving site-specific modification of DNA (e.g., genomic modification), epigenomic engineering, transcriptome regulation, genome targeting.Type: ApplicationFiled: February 25, 2021Publication date: February 2, 2023Inventors: Ervin WELKER, Péter KULCSÁR, András TÁLAS, Eszter TÓTH, Zoltán LIGETI, Antal NYESTE, Zsombor WELKER
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Patent number: 11453853Abstract: The present invention relates to a process for cleaning a solid support of a fermentation reactor for the production of alcohols by fermentation using a sugary fluid, the solid support comprising a polyurethane foam inoculated with a biomass produced by a solvent-producing strain belonging to the genus Clostridium, the process comprising placing the solid support in contact with a fluid originating from the fermentation must enriched in alcohol and/or acetone and/or an aqueous solution at basic pH.Type: GrantFiled: September 26, 2019Date of Patent: September 27, 2022Assignee: IFP Energies NouvellesInventors: Helena Gonzalez Penas, Marcel Ropars, Eszter Toth, Belinda Perez Bibbins, Nicolas Lopes Ferreira, Vincent Coupard, Angelique Bisson, Jean-Christophe Gabelle
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Publication number: 20220041972Abstract: The present invention relates to a process for cleaning a solid support of a fermentation reactor for the production of alcohols by fermentation using a sugary fluid, the solid support comprising a polyurethane foam inoculated with a biomass produced by a solvent-producing strain belonging to the genus Clostridium, the process comprising placing the solid support in contact with a fluid originating from the fermentation must enriched in alcohol and/or acetone and/or an aqueous solution at basic pH.Type: ApplicationFiled: September 26, 2019Publication date: February 10, 2022Applicant: IFP Energies NouvellesInventors: Helena GONZALEZ PENAS, Marcel ROPARS, Eszter TOTH, Belinda PEREZ BIBBINS, Nicolas LOPES FERREIRA, Vincent COUPARD, Angelique BISSON, Jean-Christophe GABELLE
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Publication number: 20210340480Abstract: The present invention relates to a process for producing alcohols, in which a sugary fluid is introduced into a fermentation reactor (2) to produce a fermentation must enriched in isopropanol, butanol, ethanol and acetone relative to the sugary fluid, the fermentation reactor (2) comprising a biomass produced by a strain belonging to the genus Clostridium which is supported on a solid support (9) comprising a polyurethane foam; and to a fermentation reactor (2) comprising said biomass supported on said solid support (9).Type: ApplicationFiled: September 26, 2019Publication date: November 4, 2021Applicant: IFP Energies nouvellesInventors: Helena GONZALEZ PENAS, Marcel ROPARS, Eszter TOTH, Vincent COUPARD, Sandra MENIR, Nicolas LOPES FERREIRA
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Patent number: 10961489Abstract: The present invention concerns a process for recovering fermentation products present in a fermentation mash produced in a bioreactor (9), comprising a step a) in which a gas stream (15) is sent into the fermentation mash under pressure in order to entrain at least a portion of the products and produce a gas stream (16) which is enriched in fermentation products. The process comprises a step h) for storage of the fermentation gases and the gas stream which is sent to the step a) is constituted by the stored fermentation gases.Type: GrantFiled: May 17, 2017Date of Patent: March 30, 2021Assignee: IFP Energies nouvellesInventors: Vincent Coupard, Helena Gonzalez Penas, Eszter Toth, Mehdi Le Moel
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Publication number: 20190203162Abstract: The present invention concerns a process for recovering fermentation products present in a fermentation mash produced in a bioreactor (9), comprising a step a) in which a gas stream (15) is sent into the fermentation mash under pressure in order to entrain at least a portion of the products and produce a gas stream (16) which is enriched in fermentation products. The process comprises a step h) for storage of the fermentation gases and the gas stream which is sent to the step a) is constituted by the stored fermentation gases.Type: ApplicationFiled: May 17, 2017Publication date: July 4, 2019Applicant: IFP Energies nouvellesInventors: Vincent COUPARD, Helena GONZALEZ PENAS, Eszter TOTH, Mehdi LE MOEL
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Patent number: 9605282Abstract: The process for the production of alcohol and/or solvent from a biomass feedstock comprises the stages for pretreatment (P) of the biomass feedstock, for enzymatic hydrolysis (H1 and HF), and for fermenting the hydrolyzate (HF). To prevent solids from being sent and to facilitate operating the section for purifying the fermentation products, at least a portion of the solid material in the fermentation wine is extracted (Ex1) to obtain a stream of solid residue (11) comprising lignin and a fermentation wine (12) that is low in solid material. Then, the stream of solid residue is washed (L) with a liquid stream to recover a liquid stream that is enriched with fermentation products (16). The liquid stream that is enriched with fermentation products (16) is recycled in the enzymatic hydrolysis stage (H1) to recover any fermentation product and to increase the overall yield of the process.Type: GrantFiled: February 6, 2014Date of Patent: March 28, 2017Assignee: IFP ENERGIES NOUVELLESInventors: Caroline Aymard, Pierre-Antoine Bouillon, Stephanie Fleurier, Sylvain Louret, Larissa Perotta, Eszter Toth
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Publication number: 20160194267Abstract: In a process and apparatus for the production of carboxylic acid esters, a liquid carboxylic acid stream is fed to an upper section of a reaction zone maintained under esterification conditions. An alcohol vapour stream is fed to a lower section of the reaction zone; allowing the carboxylic acid stream to pass in countercurrent to the alcohol stream to form a liquid product stream of product ester. A refiner stream is withdrawn from at or near the top of the reaction zone and includes unreacted alcohol, water and ether by-product. The refiner stream is passed to a refining zone and treated to reduce the water content thereof to form an ether-containing stream having a water content that is lower than that of the upper stream removed from the reaction zone. This ether-containing stream is recycled to the reaction zone.Type: ApplicationFiled: September 10, 2014Publication date: July 7, 2016Applicant: Johnson Matthey Davy Technologies LimitedInventors: Adrian Francis Backes, Gabriella Eszter Toth, Michael Gavin John Williams
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Publication number: 20160017380Abstract: The process for the production of alcohol and/or solvent from a biomass feedstock comprises the stages for pretreatment (P) of the biomass feedstock, for enzymatic hydrolysis (H1 and HF), and for fermenting the hydrolyzate (HF). To prevent solids from being sent and to facilitate operating the section for purifying the fermentation products, at least a portion of the solid material in the fermentation wine is extracted (Ex1) to obtain a stream of solid residue (11) comprising lignin and a fermentation wine (12) that is low in solid material. Then, the stream of solid residue is washed (L) with a liquid stream to recover a liquid stream that is enriched with fermentation products (16). The liquid stream that is enriched with fermentation products (16) is recycled in the enzymatic hydrolysis stage (H1) to recover any fermentation product and to increase the overall yield of the process.Type: ApplicationFiled: February 6, 2014Publication date: January 21, 2016Applicant: IFP ENERGIES NOUVELLESInventors: Caroline AYMARD, Pierre-Antoine BOUILLON, Stephanie FLEURIER, Sylvain LOURET, Larissa PEROTTA, Eszter TOTH
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Patent number: 9234158Abstract: The invention relates to a continuous process for pretreatment of an oil feedstock comprising at most 20% by weight of free fatty acids by esterification of free fatty acids in which a vertical liquid/liquid contactor containing an esterification catalyst in solid form is supplied in counter-current by an alcohol feedstock comprising at least 20% by weight of an alcohol and said oil feedstock, with said contactor being operated at a temperature of between 25 and 120° C., with said contactor performing the contact in liquid-liquid counter-current between a heavy phase and a light phase, with said heavy phase being able to be either an oil-rich phase or an alcohol-rich phase.Type: GrantFiled: December 15, 2014Date of Patent: January 12, 2016Assignee: IFP Energies NouvellesInventors: Vincent Coupard, Laurent Bournay, Eszter Toth, Sylvie Maury
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Patent number: 9187770Abstract: The process for the production of alcohol and/or solvent from a biomass feedstock comprises the stages for pretreatment (P) of the biomass feedstock, for enzymatic hydrolysis (H) of the pretreated substrate, and for fermenting the hydrolyzate (F). To reduce the size of the fermenters, at least a portion of the solid residue contained in the hydrolyzate is extracted (Ex1) in such a way as to obtain a stream of solid residue (9) comprising lignin and a hydrolyzate (8) that is low in solid residue. Then, the stream of solid residue is washed (L) with a liquid stream in such a way as to recover a sugar-enriched liquid stream (15). The sugar-enriched liquid stream (15) is recycled in the enzymatic hydrolysis stage (H) to be able to upgrade the sugars without providing dilution of the streams in the process.Type: GrantFiled: March 5, 2014Date of Patent: November 17, 2015Assignee: IFP Energies NouvellesInventors: Caroline Aymard, Pierre Antoine Bouillon, Stephanie Fleurier, Sylvain Louret, Larissa Perotta, Eszter Toth
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Publication number: 20150175932Abstract: The invention relates to a continuous process for pretreatment of an oil feedstock comprising at most 20% by weight of free fatty acids by esterification of free fatty acids in which a vertical liquid/liquid contactor containing an esterification catalyst in solid form is supplied in counter-current by an alcohol feedstock comprising at least 20% by weight of an alcohol and said oil feedstock, with said contactor being operated at a temperature of between 25 and 120° C., with said contactor performing the contact in liquid-liquid counter-current between a heavy phase and a light phase, with said heavy phase being able to be either an oil-rich phase or an alcohol-rich phase.Type: ApplicationFiled: December 15, 2014Publication date: June 25, 2015Applicant: IFP Energies NouvellesInventors: Vincent COUPARD, Laurent BOURNAY, Eszter TOTH, Sylvie MAURY
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Publication number: 20140256012Abstract: The process for the production of alcohol and/or solvent from a biomass feedstock comprises the stages for pretreatment (P) of the biomass feedstock, for enzymatic hydrolysis (H) of the pretreated substrate, and for fermenting the hydrolyzate (F). To reduce the size of the fermenters, at least a portion of the solid residue contained in the hydrolyzate is extracted (Ex1) in such a way as to obtain a stream of solid residue (9) comprising lignin and a hydrolyzate (8) that is low in solid residue. Then, the stream of solid residue is washed (L) with a liquid stream in such a way as to recover a sugar-enriched liquid stream (15). The sugar-enriched liquid stream (15) is recycled in the enzymatic hydrolysis stage (H) to be able to upgrade the sugars without providing dilution of the streams in the process.Type: ApplicationFiled: March 5, 2014Publication date: September 11, 2014Applicant: IFP ENERGIES NOUVELLESInventors: Caroline AYMARD, Pierre Antoine BOUILLON, Stephanie FLEURIER, Sylvain LOURET, Larissa PEROTTA, Eszter TOTH
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Patent number: 8466304Abstract: The present invention describes a method of producing fatty acid alkyl esters and glycerin implementing a set of transesterification reactions between a vegetable or animal oil and an aliphatic monoalcohol in the presence of a heterogeneous solid catalyst so as to obtain an effluent comprising at least alkyl esters, free glycerol, bonded glycerol and alcohol, wherein at least one stage of separation of at least a portion of the effluent is carried out in order to separate the ester produced and the bonded glycerol, said separation occurring through a membrane.Type: GrantFiled: December 22, 2009Date of Patent: June 18, 2013Assignee: IFP Energies NouvellesInventors: Arnaud Baudot, Laurent Bournay, Eszter Toth
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Patent number: 7985331Abstract: The liquid hydrocarbon stream including COS is introduced via line 1 into membrane contactor CM to be placed in contact, through membrane M, with the aqueous alkanolamine solution arriving via line 3. The COS contained in the hydrocarbon stream is absorbed by the aqueous alkanolamine solution. The liquid hydrocarbons from which the COS has been removed are evacuated from CM via line 2. The aqueous solution containing COS is sent via line 4 to zone R to be regenerated. The compounds released during regeneration, particularly COS and COS-derived products, are evacuated from zone R via line 5. The regenerated aqueous alkanolamine solution is recycled via line 3 into membrane contactor CM.Type: GrantFiled: July 11, 2006Date of Patent: July 26, 2011Assignee: Institut Francais du PetroleInventors: Arnaud Baudot, Renaud Cadours, Raphaël Huyghe, Elsa Jolimaitre, Pascal Mougin, Eszter Toth
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Publication number: 20100186290Abstract: The present invention describes a method of producing fatty acid alkyl esters and glycerin implementing a set of transesterification reactions between a vegetable or animal oil and an aliphatic monoalcohol in the presence of a heterogeneous solid catalyst so as to obtain an effluent comprising at least alkyl esters, free glycerol, bonded glycerol and alcohol, wherein at least one stage of separation of at least a portion of the effluent is carried out in order to separate the ester produced and the bonded glycerol, said separation occurring through a membrane. The invention describes the facility in which said alkyl ester production method is implemented.Type: ApplicationFiled: December 22, 2009Publication date: July 29, 2010Applicant: IFPInventors: Arnaud Baudot, Laurent Bournay, Eszter Toth
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Publication number: 20090127164Abstract: The liquid hydrocarbon stream including COS is introduced via line 1 into membrane contactor CM to be placed in contact, through membrane M, with the aqueous alkanolamine solution arriving via line 3. The COS contained in the hydrocarbon stream is absorbed by the aqueous alkanolamine solution. The liquid hydrocarbons from which the COS has been removed are evacuated from CM via line 2. The aqueous solution containing COS is sent via line 4 to zone R to be regenerated. The compounds released during regeneration, particularly COS and COS-derived products, are evacuated from zone R via line 5. The regenerated aqueous alkanolamine solution is recycled via line 3 into membrane contactor CM.Type: ApplicationFiled: July 11, 2006Publication date: May 21, 2009Inventors: Arnaud Baudot, Renaud Cadours, Raphael Huyghe, Elsa Jolimaitre, Pascal Mougin, Eszter Toth
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Patent number: 7449049Abstract: The raw natural gas is deacidized and dehydrated in units DA and DH. The treated gas is then purified by adsorption of the mercaptans in first enclosure A1. Part of the purified gas is heated in E1, then fed into second enclosure A2 so as to discharge the water adsorbed by the adsorbent material contained in this second enclosure. A steam-rich stream is fed into third enclosure A3 containing a mercaptan-laden adsorbent material. In A3, the mercaptans are desorbed and replaced by the steam.Type: GrantFiled: March 3, 2006Date of Patent: November 11, 2008Assignee: Institute Francais du PetroleInventors: Michel Thomas, Eszter Toth, Fabrice Lecomte, Peter Meyer, Jean-Louis Ambrosino