Abstract: Oral hygiene compositions including pharmacologically active ingredients extracted from one or more species of plants (or interbred strains thereof) in the Cannabis genus. In an embodiment, an extraction process may include techniques to maximize the ratio of tetrahydrocannabinolic acid (“THCA”) to tetrahydrocannabinaol (THC) in the essential oil extract, in order to maximize the presence of the non-euphoric THCA. In an embodiment, a mouthwash composition is provided. In an embodiment, an essential oil extract may be applied neat. In an embodiment, an essential oil extract may be mixed with food grade carriers (e.g. glycerol, or vegetable oil) and/or diluents (e.g. water, ethanol), and used as mouth rinse, in a conventional rinse and spit fashion. In an embodiment, an essential oil extract may be mixed with food grade carries and/or diluents and used as an ingestible composition, in a rise and swallow fashion.