Abstract: In one aspect, compositions are described herein, and in another aspect methods are described herein. In some embodiments, a polymerizable composition described herein comprises (i) one or more alkoxylated or alkenoxylated, or non-alkoxylated and non-alkenoxylated, citric acid, citrate, or ester/amide of citric acid; (ii) a polyol or polyamine such as a diel or diamine; and (iii) at least one of an associated or dissociated salt comprising a monovalent, divalent, or trivalent metal cation. In some cases, the polymerizable composition comprises additional monomers. In some cases, a composition described herein comprises a polymer or oligomer formed from a polymerizable compositions described herein. In other instances, a self-setting composite material comprising a mixture of a metal oxide crosslinker and a citrate based polymer, as well as methods of preparing same, are described herein.

Abstract: The present disclosure provides compositions which may be used as tissue engineering materials, and more particularly xylitol-doped citrate polymer compositions which may be useful as bone grafts.

Abstract: Embodiments relate to a crosslinked citrate-based elastomer catheter that is biodegradable and kink resistant. Embodiments of the crosslinked citrate-based elastomer material swells when surrounded by fluid (body fluid) so as to anchor the catheter to tissue but not anchor it so much that movement or removal will cause tissue damage. The catheter can be used as a component to a peripheral nerve block device, for example. Embodiments of the catheter can include embedding biodegradable sensors, moieties, shape memory material, etc. to monitor and modulate functions of the catheter and/or peripheral nerve block.

Abstract: In one aspect, compositions are described herein, and in another aspect methods are described herein. In some embodiments, a polymerizable composition described herein comprises (i) one or more alkoxylated or alkenoxylated, or non-alkoxylated and non-alkenoxylated, citric acid, citrate, or ester/amide of citric acid; (ii) a polyol or polyamine such as a diol or diamine; and (iii) at least one of an associated or dissociated salt comprising a monovalent, divalent, or trivalent metal cation. In some cases, the polymerizable composition comprises additional monomers. In some cases, a composition described herein comprises a polymer or oligomer formed from a polymerizable compositions described herein. In other instances, a self-setting composite material comprising a mixture of a metal oxide crosslinker and a citrate based polymer, as well as methods of preparing same, are described herein.