Abstract: The present invention provides a transgenic strain for producing succinate. The transgenic strain comprises an autotrophic host cell, and a plurality of exogenous genes within the host cell. The exogenous genes include a gene for expressing ?-ketoglutarate decarboxylase (Kgd), a gene for expressing succinate semialdehyde dehydrogenase (GabD), a gene for expressing citrate synthase (GltA) and a gene for expressing phosphoenolpyruvate carboxylase (Ppc). Further, expression of at least one of the native genes encoding glucose-1-phosphate adenylyltransferase (GlgC), succinate dehydrogenase subunit A (SdhA), and succinate dehydrogenase subunit B (SdhB) is suppressed in the host cell. The present invention further provides a method for producing succinate, which comprises: providing a transgenic strain of the present invention, and culturing the transgenic strain under a preset condition.

Abstract: Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.

Abstract: Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-l-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.