Patents by Inventor Ethan Lam
Ethan Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12252724Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.Type: GrantFiled: January 30, 2023Date of Patent: March 18, 2025Assignee: DSM IP ASSETS B.V.Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge
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Publication number: 20240279706Abstract: The present invention is related to a novel process for production of retinyl acetate in a host cell, particularly oleaginous yeast such as e.g. Yarrowia, wherein the product purity could be increased with reduction of unwanted side-products. Particularly, the novel process comprises fermentation in the presence of ethanol, such as e.g. in a fed-batch fermentation process. Such process is especially useful in a biotechnological process for production of vitamin A.Type: ApplicationFiled: July 27, 2021Publication date: August 22, 2024Inventors: Peter Louis HOUSTON, Valmik Kanubhai VYAS, Anna SYMBOR-NAGRABSKA, Reed Chadbourne DOTEN, Christopher Mark FARRELL, Ethan LAM
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Patent number: 12049658Abstract: The present invention is related to production of retinyl esters, such as in particular retinyl acetate, an important building block for production of vitamin A. The retinyl esters might be generated via enzymatic conversion of retinol which process includes the use of enzymes with acetyl-transferase (ATF) activity, thus acetylating retinol into retinol/retinyl acetate. Said process is particularly useful for biotechnological production of vitamin A.Type: GrantFiled: September 25, 2018Date of Patent: July 30, 2024Assignee: DSM IP Assets B.V.Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna Mcmahon, Joshua Trueheart, Celine Viarouge, René Marcel De Jong
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Publication number: 20240218336Abstract: The present invention is related to a novel enzymatic process for production of vitamin A alcohol (retinol) via conversion of retinal, which process includes the use of heterologous enzymes having activity as retinal reductase, particularly wherein the reaction leads to at least about 90% conversion of retinal into retinol. Said process is particularly useful for biotechnological production of vitamin A.Type: ApplicationFiled: February 13, 2024Publication date: July 4, 2024Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Patent number: 11905542Abstract: The present invention is related to a novel enzymatic process for production of retinyl esters, such as in particular retinyl long chain esters, via conversion of retinol, which process includes the use of enzymes having acyltransferase activity. Said process might be used for biotechnological production of vitamin A.Type: GrantFiled: September 25, 2018Date of Patent: February 20, 2024Assignee: DSM IP ASSETS B.V.Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge
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Publication number: 20230265443Abstract: The present invention is related to a novel process for production of retinyl acetate in a host cell, particularly oleaginous yeast such as e.g. Yarrowia, growing on triglyceride oils, such as e.g. vegetable oil, wherein the host cell exhibits modified lipase activity in such a way that conversion of retinol into fatty acid retinyl esters (FAREs) is reduced or abolished. Such process is especially useful in a biotechnological process for production of vitamin A.Type: ApplicationFiled: July 22, 2021Publication date: August 24, 2023Inventors: Peter Louis HOUSTON, Valmik Kanubhai VYAS, René Marcel DE JONG, Anna SYMBOR-NAGRABSKA, Ethan LAM
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Publication number: 20230227862Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.Type: ApplicationFiled: January 30, 2023Publication date: July 20, 2023Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Patent number: 11578344Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.Type: GrantFiled: September 25, 2018Date of Patent: February 14, 2023Assignee: DSM IP ASSETS B.V.Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge
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Publication number: 20200277644Abstract: The present invention is related to a novel enzymatic process for production of vitamin A aldehyde (retinal) via stereoselective conversion of beta-carotene which process includes the use of trans-selective enzymes having activity as beta-carotene oxidases (BCOs), in particular having preference for trans-retinal. 5 Said process is in particular useful for biotechnological production of vitamin A.Type: ApplicationFiled: September 25, 2018Publication date: September 3, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE, René Marcel DE JONG
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Publication number: 20200248151Abstract: The present invention is related to a novel enzymatic process for production of vitamin A alcohol (retinol) via conversion of retinal, which process includes the use of heterologous enzymes having activity as retinal reductase, particularly wherein the reaction leads to at least about 90% conversion of retinal into retinol. Said process is particularly useful for biotechnological production of vitamin A.Type: ApplicationFiled: September 25, 2018Publication date: August 6, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Publication number: 20200239924Abstract: The present invention is related to a novel enzymatic process for production of retinyl esters, such as in particular retinyl long chain esters, via conversion of retinol, which process includes the use of enzymes having acyltransferase activity. Said process might be used for biotechnological production of vitamin A.Type: ApplicationFiled: September 25, 2018Publication date: July 30, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Publication number: 20200239925Abstract: The present invention is related to production of retinyl esters, such as in particular retinyl acetate, an important building block for production of vitamin A. The retinyl esters might be generated via enzymatic conversion of retinol which process includes the use of enzymes with acetyl-transferase (ATF) activity, thus acetylating retinol into retinol/retinyl acetate. Said process is particularly useful for biotechnological production of vitamin A.Type: ApplicationFiled: September 25, 2018Publication date: July 30, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE, René Marcel DE JONG
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Publication number: 20200231993Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.Type: ApplicationFiled: September 25, 2018Publication date: July 23, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Publication number: 20140352756Abstract: The Solar Balloon Photovoltaic Array is comprised of a solar balloon supporting and lifting an array of very thin, light weight, and flexible solar photovoltaic sheet array which is attached to an electrical wire cord tethered to the solar balloon at one end, and securely tied to a structure on the ground surface at the terminal output end. The solar balloon is deployed into the atmosphere by the heating of the air inside the solar balloon by direct sunlight as well as by an electrical heating element inside the solar balloon. The solar balloon is first partially inflated on the ground surface and then fully inflated by solar energy heating the air inside the balloon, which fully inflates the solar balloon to provide sufficient buoyancy lifting force to lift the solar array into the sky, forming a vertical solar photovoltaic array to provide solar generated electricity for household consumption.Type: ApplicationFiled: June 1, 2013Publication date: December 4, 2014Inventors: Vinh Minh Glisttenmeer Lam, Ethan Lam, Megan Lam, Victor Lam
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Publication number: 20140311559Abstract: We describe an invention, the Photovoltaic Solar Leaf Module, comprising of an active photovoltaic (PV) thin film layer being sandwiched and laminated by two sheets of light trapping surface textured polymer, which also form a durable, light weight and flexible protective casing around the active PV thin film layer, which is capable of absorbing sunlight on its front and back surfaces. A method of mounting our PV leaf module is described whereby many PV solar leaf modules are mounted in an array onto many horizontal rods, which are then mounted along a vertical pole supported by a base, which is attached to the ground surface. Another method of mounting the PV leaf module is also described whereby many PV solar leaf modules are electrically and mechanically attached to a long flexible electrical cord, forming an array of many PV solar leaf modules along the length of the flexible electrical cord.Type: ApplicationFiled: April 18, 2013Publication date: October 23, 2014Inventors: Vinh Minh Glisttenmeer Lam, Ethan Lam, Megan Lam, Victor Lam
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Publication number: 20140196765Abstract: A system of harvesting solar energy is described whereby cylindrical tubular solar photovoltaic cells are vertically mounted into a high density array with their longitudinal axis in the vertical direction.Type: ApplicationFiled: January 14, 2013Publication date: July 17, 2014Inventors: Vinh Minh Glisttenmeer Lam, Ethan Lam, Megan Lam, Victor Lam
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Publication number: 20140196432Abstract: A new type of engine module is described based on the Tesla turbine. Our Tesla Twin Turbines Combustion Engine Module comprises of two Tesla turbines welded together, forming a combustion chamber in between. The combustion chamber includes an air-fuel mixture inlet and an ignition inlet. Fuel-air mixture is injected through the air-fuel inlet into the combustion chamber which is ignited by an ignition device. The high temperature combustion gas flow in opposite directions across 2 stacks of evenly spaced smooth parallel discs, transferring energy into rotating the discs via the mechanism of boundary layer laminar flow interaction. The pair of rotating stacks of discs rotates a pair of rods. The gas exits through exhaust holes or openings adjacent to the pair of rods. The rotating rods can be used to drive generators or do useful works.Type: ApplicationFiled: January 14, 2013Publication date: July 17, 2014Inventors: Vinh Minh Glisttenmeer Lam, ETHAN LAM, MEGAN LAM, VICTOR LAM
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Publication number: 20140176363Abstract: A method for tracking extremely dangerous weapons, such as assault rifles, is described. This method comprises of a GPS device which is strapped onto the weapon, such as the assault rifle's neck. The position of the GPS, along with the location of the weapon is constantly monitored. If the position of the GPS and weapon is near a school, an alarm signal is sent to a Global Position Processing Center. The Center then immediately contact and inform the school and the local police department about the position of the weapon by its GPS positional signal. If the GPS is disabled, an alarm signal is sent to the Center. The Center then investigates the reason for its disablement. If the disablement of the GPS is illegal, then the Center will contact the local police for further investigation of the weapon. In this way, dangerous weapons, such as assault rifles, are kept track of and schools are alerted when such weapons come within its safety perimeter.Type: ApplicationFiled: December 25, 2012Publication date: June 26, 2014Inventors: Vinh Minh Glisttenmeer Lam, Ethan Lam, Megan Lam