Patents by Inventor Ethan Lerner

Ethan Lerner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prevention and treatment of itch with cysteine protease inhibition
    Patent number: 8852569
    Abstract: Embodiments of the invention relates to methods of preventing itch in a subject using an therapeutically effective amount of a cysteine protease inhibitor. The itch is not associated with psoriasis and atopic dermatitis. The itch is also a non-histamine mediated itch. The cysteine protease inhibitor is an inhibitor directed to cathepsin S.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: October 7, 2014
    Assignee: The General Hospital Corporation
    Inventors: Ethan Lerner, Vemuri B. Reddy
  • PREVENTION AND TREATMENT OF ITCH WITH CYSTEINE PROTEASE INHIBITION
    Publication number: 20110184016
    Abstract: Embodiments of the invention relates to methods of preventing itch in a subject using a therapeutically effective amount of a cysteine protease inhibitor. The itch is not associated with psoriasis and atopic dermatitis. The itch is also a non-histamine mediated itch. The inhibitor are directed to the cathepsin selected from the group consisting of cathepsin B, C, F, J, K, H, L, P, Q, S, W, X, V, and Z.
    Type: Application
    Filed: August 28, 2009
    Publication date: July 28, 2011
    Applicant: The General Hospital Corporation
    Inventors: Ethan Lerner, Vemuri B. Reddy
  • METHODS OF TREATING ITCH
    Publication number: 20080213252
    Abstract: The invention provides methods for preventing and/or treating itch in a subject in need thereof by administration of a protease-activated G-protein coupled Protease Activated Receptor 4 (PAR4) antagonist. The PAR4 antagonist can be combined with a PAR2 antagonist.
    Type: Application
    Filed: January 3, 2008
    Publication date: September 4, 2008
    Inventors: Ethan LERNER, Vemuri B. REDDY
  • NOS inhibitors for treatment of wrinkles
    Publication number: 20030207844
    Abstract: Methods, compositions, and kits, are provided for the use of nitric oxide synthase inhibitors to prevent and reduce wrinkles.
    Type: Application
    Filed: April 3, 2003
    Publication date: November 6, 2003
    Applicant: The General Hospital Corporation, a Massachusetts corporation
    Inventors: Ethan Lerner, Seishiro Fujii
  • NOS inhibitors for treatment of wrinkles
    Publication number: 20020168325
    Abstract: Methods, compositions, and kits, are provided for the use of nitric oxide synthase inhibitors to prevent and reduce wrinkles.
    Type: Application
    Filed: January 25, 2002
    Publication date: November 14, 2002
    Inventors: Ethan Lerner, Seishiro Fujii