Patents by Inventor Ethel C. Garnier-Amblard

Ethel C. Garnier-Amblard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thieno[2,3-D]pyrimidin-4-one Derivatives as NMDAR Modulators and Uses Related Thereto
    Publication number: 20170313719
    Abstract: The disclosure relates thieno[2,3-d]pyrimidin-4-one derivatives as modulators of NMDA receptors and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for managing conditions related to cognition, typically prevention or treatment of neurological conditions related to the NMDA receptor.
    Type: Application
    Filed: November 18, 2015
    Publication date: November 2, 2017
    Inventors: Stephen F. Traynelis, Lanny S. Liebeskind, Dennis C. Liotta, Ethel C. Garnier-Amblard, PavanKumar Reddy Gangireddy
  • Methods of Preparing 1-Deoxy-Sphingoid Bases and Derivatives Thereof
    Publication number: 20110282081
    Abstract: Novel methods of synthesizing 1-deoxy-sphingoid bases and derivatives are disclosed. The synthesis is achieved from commercially available and inexpensive starting materials. The process includes thioesterification, cross-coupling, and reduction. The process may also include directed epoxidation, regioselective epoxide-opening, hydrogenation, and dihydroxylation. The methods described herein provide 1-deoxy-sphingoid bases and derivatives in high overall yield and high enantiomeric purity.
    Type: Application
    Filed: January 21, 2010
    Publication date: November 17, 2011
    Applicant: EMORY UNIVERSITY
    Inventors: Lanny S. Liebeskind, Ethel C. Garnier-Amblard, Dennis C. Liotta