Patents by Inventor Etienne Honore Schacht

Etienne Honore Schacht has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functional poly-?-amino-acid derivatives useful for the modification of biologically active materials and their application
    Patent number: 7005123
    Abstract: A linear poly-?-amino-acid derivative has at least glutamic or aspartic or serinic repeating units and additionally having a functional group at one or both ends of the polymer backbone and/or only a single functional group as a side group on the polymer backbone, the said functional end group and/or side group being other than alcohol. The said functional derivative is useful for the modification of biologically active materials.
    Type: Grant
    Filed: June 19, 2000
    Date of Patent: February 28, 2006
    Assignee: Universiteit Gent
    Inventors: Etienne Honoré Schacht, Veska Toncheva
  • Composition of crosslinkable prepolymers for biodegradable implants
    Patent number: 6933328
    Abstract: A composition suitable for preparing a biodegradable implant, comprising a crosslinkable multifunctional prepolymer having at least two polymerizable end groups, the said composition having a viscosity such that it is deformable at a temperature of 0° to 60° C. into a three-dimensional shape and being crosslinkable within the said temperature range. The prepolymer comprises a hydrophilic region and/or the composition further comprises an effective amount of a mineral biologically-active component delivery system and/or a biocompatible degradable porosity-inducing component.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: August 23, 2005
    Assignee: Universiteit Gent
    Inventor: Etienne Honoré Schacht
  • Polymer microspheres and a method of production thereof
    Patent number: 5922357
    Abstract: The invention relates to microspheres which are suitable for biomedical uses which have a diameter in the range of 10 nm to 2 mm and which comprise a substantially spherical core particle of a non-water-soluble polymer and an outer surface layer consisting substantially of a water-soluble polymer. The water-soluble polymer is conjugated to polyethylene glycol and the non-water-soluble core particle is attached to the water-soluble polymer by the polyethylene glycol moiety. The microspheres are prepared by dissolving the non-water-soluble polymer in a suitable first solvent, dispersing the polymer solution in a solution of the PEG/water-soluble polymer conjugate and evaporating the first solvent to form microspheres in which the PEG anchors the water-soluble polymer to the core particle.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: July 13, 1999
    Assignees: University of Nottingham, University of Gent
    Inventors: Allan Gerald Arthur Coombes, Stanley Stewart Davis, Etienne Honore Schacht
  • Drug delivery agents incorporating mitomycin
    Patent number: 5738864
    Abstract: A conjugate of a carrier polymer and aziridine ring containing mitomycin (MMC) drug molecules is prepared by coupling the MMC molecules via their aziridine imino groups to spacer groups that terminate in protected amino groups, deprotecting said amino groups, recovering and purifying the spacer-MMC derivatives, and then coupling these derivatives via said deprotected amino groups to the carrier polymer. Alternatively, the MMC may first be treated with an activating agent, e.g. carbodiimidazole, to form an activated MMC derivative which is then coupled directly to spacer groups linked to the carrier polymer.
    Type: Grant
    Filed: February 20, 1996
    Date of Patent: April 14, 1998
    Assignee: European Community
    Inventors: Etienne Honore Schacht, Ruth Duncan, Paolo Ferruti