Patents by Inventor Etienne Slabbert

Etienne Slabbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted depletion of non-target library molecules using poison primers during target capture of next-generation sequencing libraries
    Patent number: 12590328
    Abstract: The present disclosure is directed to compositions, kits, and methods of target enrichment by unidirectional primer extension, whereby the compositions, kits, and methods utilize both poison primers and target capture primers.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: March 31, 2026
    Assignees: ROCHE SEQUENCING SOLUTIONS, INC., KAPA BIOSYSTEMS, INC.
    Inventors: Richard Dannebaum, Brian Christopher Godwin, David L. Penkler, Etienne Slabbert, Ruben van der Merwe
  • CONTROLLING FOR TAGMENTATION SEQUENCING LIBRARY INSERT SIZE USING ARCHAEAL HISTONE-LIKE PROTEINS
    Publication number: 20250368983
    Abstract: The present disclosure provides compositions and kits for the tagmentation of double stranded DNA. In some embodiments, the compositions and kits for the tagmentation of double stranded DNA include one or more histone-like proteins and/or one or more transposition systems. The present disclosure also provides methods for the tagmentation of double stranded DNA in the presence of one or more histone-like proteins.
    Type: Application
    Filed: June 30, 2023
    Publication date: December 4, 2025
    Inventors: Taariq Firfirey, Etienne Slabbert
  • Generation of single-stranded circular DNA templates for single molecule sequencing
    Patent number: 12110534
    Abstract: The invention is a novel method of sequencing nucleic acids involving making and sequencing a library of single stranded circular target nucleic acids.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: October 8, 2024
    Assignees: Roche Sequencing Solutions, Inc., Kapa Biosystems, Inc.
    Inventors: Daleen Badenhorst, Michael S. Berry, Richard Dannebaum, Ashley Hayes, Severine Margeridon, Martin Ranik, Etienne Slabbert
  • TARGETED DEPLETION OF NON-TARGET LIBRARY MOLECULES USING POISON PRIMERS DURING TARGET CAPTURE OF NEXT-GENERATION SEQUENCING LIBRARIES
    Publication number: 20240279725
    Abstract: The present disclosure is directed to compositions, kits, and methods of target enrichment by unidirectional primer extension, whereby the compositions, kits, and methods utilize both poison primers and target capture primers.
    Type: Application
    Filed: July 7, 2021
    Publication date: August 22, 2024
    Inventors: Richard Dannebaum, Brian Christopher Godwin, David L. Penkler, Etienne Slabbert, Ruben van der Merwe
  • GENERATION OF SINGLE-STRANDED CIRCULAR DNA TEMPLATES FOR SINGLE MOLECULE SEQUENCING
    Publication number: 20210115510
    Abstract: The invention is a novel method of sequencing nucleic acids involving making and sequencing a library of single stranded circular target nucleic acids.
    Type: Application
    Filed: July 31, 2020
    Publication date: April 22, 2021
    Inventors: Daleen Badenhorst, Michael S. Berry, Richard Dannebaum, Ashley Hayes, Severine Margeridon, Martin Ranik, Etienne Slabbert