Abstract: A sewing machine includes a vertical shuttle and a middle shuttle presser disposed at a front side of the vertical shuttle. The sewing machine includes a presser frame, an optical upper thread detector and a stitch skipping detection processor. The presser frame is movably supported between a pressing position at which the middle shuttle presser is pressed and a retract position separated from the pressing position. The optical upper thread detector is provided at the presser frame and is configured to detect passage of an upper thread using detecting light which passes through passage portions formed in the middle shuttle presser and which crosses a front side of a bobbin case of the vertical shuttle. The stitch skipping detection processor is configured to determine whether the passage of the upper thread is present based on an amount of received light of the detecting light from the upper thread detector.

Abstract: A sewing machine includes a vertical shuttle and a middle shuttle presser disposed at a front side of the vertical shuttle. The sewing machine includes a presser frame, an optical upper thread detector and a stitch skipping detection processor. The presser frame is movably supported between a pressing position at which the middle shuttle presser is pressed and a retract position separated from the pressing position. The optical upper thread detector is provided at the presser frame and is configured to detect passage of an upper thread using detecting light which passes through passage portions formed in the middle shuttle presser and which crosses a front side of a bobbin case of the vertical shuttle. The stitch skipping detection processor is configured to determine whether the passage of the upper thread is present based on an amount of received light of the detecting light from the upper thread detector.

Abstract: A hybridization apparatus includes at least (A) a reaction station having a reaction vessel holder, a heating-cooling device, and a magnetic force controller, (B) a tip rack/waste solution station having a tip rack and a waste solution reservoir, (C) a washing solution station having a washing solution reservoir and a heating-cooling device, and (D) a head station having an arm unit movable in X-Z directions, the arm unit including a tip setting mechanism having a 1o plurality of tip nozzles for respective tips to be attached to or detached from, and a mechanism for the attached tips to suck and inject treatment solution.