Patents by Inventor Etsuo Okuno

Etsuo Okuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant KAT enzyme and process for its preparation
    Patent number: 6136572
    Abstract: Disclosed are isolated DNAs encoding a kynurenine aminotransferase selected from the group consisting of:(a) isolated DNA sequences which encode rat KAT;(b) an isolated DNA sequence which hybridizes to isolated DNA sequences of (a) above and which encodes a mammalian KAT enzyme; and(c) an isolated DNA sequence differing from the isolated DNA sequences of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a KAT enzyme.Vectors and host cells containing the same, oligonucleotide probes for identifying kynurenine aminotransferase, and isolated and purified kynurenine aminotransferase are also disclosed.
    Type: Grant
    Filed: April 1, 1997
    Date of Patent: October 24, 2000
    Assignees: University of Maryland at Baltimore, Pharmacia & Upjohn S.P.A.
    Inventors: Luca Benatti, Jerome Breton, Carmela Speciale, Etsuo Okuno, Robert Schwarcz, Monica Mosca
  • Recombinant kat enzyme from rat
    Patent number: 5817496
    Abstract: Disclosed are isolated DNAs encoding a kynurenine aminotransferase selected from the group consisting of: (a) an isolated DNA sequence which encodes rat KAT; (b) an isolated DNA sequence which hybridizes to the isolated DNA sequence of (a) above and which encodes a KAT enzyme; and (c) an isolated DNA sequence differing from the isolated DNA sequences of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a KAT enzyme. Also disclosed are vectors and host cells containing the same; oligonucleotide probes for identifying kynurenine aminotransferase; and isolated and purified kynurenine aminotransferase.
    Type: Grant
    Filed: July 7, 1994
    Date of Patent: October 6, 1998
    Assignees: Pharmacia & UpJohn S.P.A., University of Maryland at Baltimore
    Inventors: Luca Benatti, Jerome Breton, Carmela Speciale, Etsuo Okuno, Robert Schwarcz, Monica Mosca