Abstract: A through-hole panel is mounted on a barrier between a hot zone maintained at a selected isolation level and a cold zone not maintained at the selected isolation level. Hermetically sealed electrical feedthroughs each include a housing and cold- and hot-side electrical receptacles, and are hermetically sealed into through-holes of the through-hole panel with the cold- and hot-side electrical receptacles extending into the respective cold and hot zones. A surface of the through-hole panel and a portion of the feedthroughs exposed to the hot zone are substantially resistant to corrosive decontamination agents used in the hot zone. A medical imaging instrument in the cold zone images an interior volume of a generally tubular imaging window that is in communication with the hot zone and is isolated from the cold zone. An auxiliary instrument in the hot zone operatively electrically communicates with the medical imaging instrument via the feedthroughs.