Abstract: A collapsible syringe assembly for a fluid delivery system is a multi-component device that includes a cylindrical pressure jacket and a collapsible syringe that is received within the pressure jacket. The collapsible syringe includes a cap member and a compressible or deformable sidewall member. The collapsible syringe in one embodiment is adapted to be secured to the pressure jacket by the cap member. The cap member is formed with a discharge port, which may be formed as conventional luer fitting. The discharge port is disposed coaxially within an annular wall on the outward facing side of the cap member and may be recessed within the annular wall.

Abstract: A collapsible syringe assembly for a fluid delivery system is a multi-component device that includes a cylindrical pressure jacket and a collapsible syringe that is received within the pressure jacket. The collapsible syringe includes a cap member and a compressible or deformable sidewall member. The collapsible syringe in one embodiment is adapted to be secured to the pressure jacket by the cap member. The cap member is formed with a discharge port, which may be formed as conventional luer fitting. The discharge port is disposed coaxially within an annular wall on the outward facing side of the cap member and may be recessed within the annular wall.

Abstract: A bellows assembly for a fluid delivery system is a multi-component device that includes a cylindrical pressure jacket and a bellows syringe that is received within the pressure jacket. The bellows syringe includes a cap member and a bellows member. The bellows syringe in one embodiment is adapted to be secured to the pressure jacket by the cap member. The cap member is formed with a discharge port, which may be formed as conventional luer fitting. The discharge port is disposed coaxially within an annular wall on the outward facing side of the cap member and may be recessed within the annular wall. The bellows member is a hollow body that includes a series of bellows sections or rings. A distal end of the bellow member is formed with a discharge neck terminating in a discharge port, and the proximal end is formed with a closed end wall.

Abstract: A method and device for the simultaneous or sequential introduction of multiple fluids into the bloodstream including a multiple lumen catheter with corresponding multiple hole sets. By introducing a second fluid such as saline, the concentration and bolus of a first fluid, such as a contrast agent, can be controlled and optimized.

Abstract: A bellows assembly for a fluid delivery system is a multi-component device that includes a cylindrical pressure jacket and a bellows syringe that is received within the pressure jacket. The bellows syringe includes a cap member and a bellows member. The bellows syringe in one embodiment is adapted to be secured to the pressure jacket by the cap member. The cap member is formed with a discharge port, which may be formed as conventional luer fitting. The discharge port is disposed coaxially within an annular wall on the outward facing side of the cap member and may be recessed within the annular wall. The bellows member is a hollow body that includes a series of bellows sections or rings. A distal end of the bellow member is formed with a discharge neck terminating in a discharge port, and the proximal end is formed with a closed end wall.

Abstract: A method and device for the simultaneous or sequential introduction of multiple fluids into the bloodstream including a multiple lumen catheter with corresponding multiple hole sets. By introducing a second fluid such as saline, the concentration and bolus of a first fluid, such as a contrast agent, can be controlled and optimized.

Abstract: Systems, devices, and methods towards improved diagnosis and therapy in connection with central venous catheters (including PICC lines). Included among the many improvements broadly contemplated herein are: arrangements via which a venous catheter can move passively into position in central venous circulation; arrangements via which a catheter can be actively guided without the use of a needle or guide wire; arrangements via which a catheter can be packaged to facilitate easy, rapid, and positionally accurate deployment by medical personnel while maintaining device sterility; and arrangements via which a catheter tip can be imaged during and after insertion.

Abstract: A system for delivering a fluid comprising cells to tissue of a patient, includes: a least a first container for holding an injection fluid in which the agent is carried; a first powered drive in operative connection with the container, the first powered drive being operable to pressurize contents of the container; a control system in operative connection with the first powered drive and operative to control the first powered drive; a fluid path in fluid connection with the container, the fluid path including a patient interface adapted to deposit the cells within tissue of the patient; a sensor system; and a communication system in connection with at least the control system and the sensor system. The communication system is adapted to provide information to the control system. The control system in adapted to transmit a control signal to at least the first powered drive based at least in part on information provided to the control system. The cells can for example be pregenitor cells or stem cells.

Abstract: The fluid injection apparatus includes an injector having an injector head and a drive piston extendable from the injector head. A pressure jacket is engaged with the injector head and defines a receiving opening. An adaptor pump is inserted into the receiving bore in the pressure jacket. The adaptor pump includes a pressurizing body in which a pressurizing plunger is seated. The pressurizing body is in fluid communication with a container body defining an internal chamber which is pressurized by the action of the plunger in the pressurizing body. The container body defines an opening allowing access to the internal or pressurizing chamber for accepting a pinch sleeve into the container body. The pinch sleeve is inserted into the container body through the opening and is disposed in the pressurizing chamber. The pinch sleeve is adapted to receive a flexible or collapsible pouch containing medical liquid.

Abstract: A system for injecting an injectate into patient includes a first pressurizable container for holding the injectate; a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient; a powered injector in operative connection with the first pressurizable container to pressurize the injectate; a controller system in operative connection with powered injector; and a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system.

Abstract: An injector system includes an injector and a syringe. The injector includes a housing having a front wall, a drive member moveable through the front wall of the housing, and a pressure jacket assembly for operably associating the syringe with the housing. The pressure jacket assembly includes a rearward end mounted on the front wall of the housing and a forward open end for receiving the syringe therethrough. The syringe includes a body having a main section, a conical section in fluid communication with the main section and a fluid discharge section in fluid communication with the conical section. The syringe further includes a plunger movably disposed in the body. The plunger includes one or more hook members extending rearward from the plunger for connecting the plunger to the drive member of the injector. The syringe also includes a protrusion for facilitating handling of the syringe. Preferably, the protrusion is operably associated with and extends forwardly from the conical section of the body.

Abstract: An injector system includes a syringe and an injector. The syringe includes a body portion and a plunger movably disposed within the body portion. The injector includes a housing defining a front opening therein, a drive member extendible through the front opening of the housing for imparting motive force to the plunger disposed within the syringe, and a pressure jacket assembly associated with the housing for substantially enclosing the syringe during an injection procedure. The pressure jacket assembly includes a jacket cylinder having an open front end for receiving the syringe and a front member associated with the housing. The front member is pivotable between a closed position for retaining the syringe within the jacket cylinder and an open position for allowing the syringe to be inserted into and removed from the front end of the jacket cylinder.

Abstract: An injection apparatus for use with a syringe is provided. The injection apparatus includes an injector and a pressure jacket assembly. The injector preferably includes a housing defining a front opening and a drive piston extendible through the front opening for imparting motive force to a plunger disposed within the syringe. The pressure jacket assembly preferably includes a jacket cylinder having a rear end coupled to the injector housing and an open front end for receiving the syringe therethrough, a support member having a rear end pivotally coupled to the injector housing and a front end, and a front member pivotally coupled to the front end of the support member. Preferably, the front member is pivotable between a closed position for retaining the syringe within the jacket cylinder and an open position for allowing the syringe to be inserted into and removed from the front end of the jacket cylinder.

Abstract: An injector system includes an injector and a syringe. The injector includes a housing having a front wall, a drive member moveable through the front wall of the housing, and a pressure jacket assembly for operably associating the syringe with the housing. The pressure jacket assembly includes a rearward end mounted on the front wall of the housing and a forward open end for receiving the syringe therethrough. The syringe includes a body having a main section, a conical section in fluid communication with the main section and a fluid discharge section in fluid communication with the conical section. The syringe further includes a plunger movably disposed in the body. The plunger includes one or more hook members extending rearward from the plunger for connecting the plunger to the drive member of the injector. The syringe also includes a protrusion for facilitating handling of the syringe. Preferably, the protrusion is operably associated with and extends forwardly from the conical section of the body.

Abstract: A front-loading syringe, which comprises a movable plunger for injecting liquid contrast media, is mountable on a front wall of an injector housing having a pressure jacket, by a first quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An injection end of the syringe may include loop-shaped reinforcing handle portions.

Abstract: An injection apparatus for use with a syringe is provided. The injection apparatus includes an injector and a pressure jacket assembly. The injector preferably includes a housing defining a front opening and a drive piston extendible through the front opening for imparting motive force to a plunger disposed within the syringe. The pressure jacket assembly preferably includes a jacket cylinder having a rear end coupled to the injector housing and an open front end for receiving the syringe therethrough, a support member having a rear end pivotally coupled to the injector housing and a front end, and a front member pivotally coupled to the front end of the support member. Preferably, the front member is pivotable between a closed position for retaining the syringe within the jacket cylinder and an open position for allowing the syringe to be inserted into and removed from the front end of the jacket cylinder.

Abstract: A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs, which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background.

Abstract: An injector system includes a syringe and an injector. The syringe includes a body portion and a plunger movably disposed within the body portion. The injector includes a housing defining a front opening therein, a drive member extendible through the front opening of the housing for imparting motive force to the plunger disposed within the syringe, and a pressure jacket assembly associated with the housing for substantially enclosing the syringe during an injection procedure. The pressure jacket assembly includes a jacket cylinder having an open front end for receiving the syringe and a front member associated with the housing. The front member is pivotable between a closed position for retaining the syringe within the jacket cylinder and an open position for allowing the syringe to be inserted into and removed from the front end of the jacket cylinder.

Abstract: A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background.

Abstract: A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs, which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background.