Patents by Inventor Eugene A. Sprague

Eugene A. Sprague has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Implantable medical devices having controlled surface properties for improved healing response
    Patent number: 10874532
    Abstract: An implantable medical device that is fabricated from materials that present a blood or body fluid or tissue contact surface that has controlled heterogeneities in material constitution. An endoluminal stent-graft and web-stent that is made of a monolithic material formed into differentiated regions defining structural members and web regions extending across interstitial spaces between the structural members. The endoluminal stent-graft is characterized by having controlled heterogeneities at the blood flow surface of the stent.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: December 29, 2020
    Assignee: Vactronix Scientific, LLC
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • Method of making recessed features on inner surface of tubular structure by thermal ablation
    Patent number: 10806614
    Abstract: The invention relates to methods and apparatus for manufacturing intravascular stents wherein the intravascular stent has its inner surface treated to promote the migration of endothelial cells onto the inner surface of the intravascular stent. In particular, the inner surface of the intravascular stent has at least one groove formed therein.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: October 20, 2020
    Assignee: Vactronix Scientific, LLC
    Inventors: Christopher E Banas, Julio C Palmaz, Eugene A Sprague
  • Method of making recessed features on inner surface of tubular structure by photolithography
    Patent number: 10758383
    Abstract: The invention relates to methods and apparatus for manufacturing intravascular stents wherein the intravascular stent has its inner surface treated to promote the migration of endothelial cells onto the inner surface of the intravascular stent. In particular, the inner surface of the intravascular stent has at least one groove formed therein.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: September 1, 2020
    Assignee: Vactronix Scientific, LLC
    Inventors: Christopher E Banas, Julio C Palmaz, Eugene A Sprague
  • Implantable biomaterials having functional surfaces
    Patent number: 10682443
    Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: June 16, 2020
    Assignee: Vactronix Scientific, LLC
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • IMPLANTABLE BIOMATERIALS HAVING FUNCTIONAL SURFACES
    Publication number: 20190307926
    Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
    Type: Application
    Filed: June 10, 2019
    Publication date: October 10, 2019
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • Method of making implantable medical devices having controlled surface properties
    Patent number: 10363125
    Abstract: An implantable medical device that is fabricated from materials that present a blood or body fluid or tissue contact surface that has controlled heterogeneities in material constitution. An endoluminal stent-graft and web-stent that is made of a monolithic material formed into differentiated regions defining structural members and web regions extending across interstitial spaces between the structural members. The endoluminal stent-graft is characterized by having controlled heterogeneities at the blood flow surface of the stent.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: July 30, 2019
    Assignee: Vactronix Scientific, LLC
    Inventors: Julio C. Palmaz, Eugene A. Sprague, Christopher E. Banas
  • Implantable biomaterials having functional surfaces
    Patent number: 10314949
    Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: June 11, 2019
    Assignee: Vactronix Scientific, LLC
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • METHOD OF MAKING IMPLANTABLE MEDICAL DEVICES HAVING CONTROLLED SURFACE PROPERTIES
    Publication number: 20190021844
    Abstract: An implantable medical device that is fabricated from materials that present a blood or body fluid or tissue contact surface that has controlled heterogeneities in material constitution. An endoluminal stent-graft and web-stent that is made of a monolithic material formed into differentiated regions defining structural members and web regions extending across interstitial spaces between the structural members. The endoluminal stent-graft is characterized by having controlled heterogeneities at the blood flow surface of the stent.
    Type: Application
    Filed: September 25, 2018
    Publication date: January 24, 2019
    Inventors: Julio C. Palmaz, Eugene A. Sprague, Christopher E. Banas
  • IMPLANTABLE BIOMATERIALS HAVING FUNCTIONAL SURFACES
    Publication number: 20180344904
    Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
    Type: Application
    Filed: July 27, 2018
    Publication date: December 6, 2018
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • Method of making implantable medical devices having controlled surface properties
    Patent number: 10092390
    Abstract: An implantable medical device that is fabricated from materials that present a blood or body fluid or tissue contact surface that has controlled heterogeneities in material constitution. An endoluminal stent-graft and web-stent that is made of a monolithic material formed into differentiated regions defining structural members and web regions extending across interstitial spaces between the structural members. The endoluminal stent-graft is characterized by having controlled heterogeneities at the blood flow surface of the stent.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: October 9, 2018
    Assignee: Vactronix Scientific, LLC
    Inventors: Julio C. Palmaz, Eugene A. Sprague, Christopher E. Banas
  • Implantable biomaterials having engineered functional surfaces
    Patent number: 10034967
    Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
    Type: Grant
    Filed: July 25, 2016
    Date of Patent: July 31, 2018
    Assignee: VACTRONIX SCIENTIFIC, LLC
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • Method of Making Recessed Features on Inner Surface of Tubular Structure by Photolithography
    Publication number: 20180133035
    Abstract: The invention relates to methods and apparatus for manufacturing intravascular stents wherein the intravascular stent has its inner surface treated to promote the migration of endothelial cells onto the inner surface of the intravascular stent. In particular, the inner surface of the intravascular stent has at least one groove formed therein.
    Type: Application
    Filed: October 16, 2017
    Publication date: May 17, 2018
    Inventors: Christopher E Banas, Julio C Palmaz, Eugene A. Sprague
  • Method of Making Recessed Features on Inner Surface of Tubular Structure by Thermal Ablation
    Publication number: 20180133036
    Abstract: The invention relates to methods and apparatus for manufacturing intravascular stents wherein the intravascular stent has its inner surface treated to promote the migration of endothelial cells onto the inner surface of the intravascular stent. In particular, the inner surface of the intravascular stent has at least one groove formed therein.
    Type: Application
    Filed: October 16, 2017
    Publication date: May 17, 2018
    Inventors: Christopher E. Banas, Julio C. Palmaz, Eugene A. Sprague
  • Method for making grooves on a luminal surface of an intravascular stent
    Patent number: 9788980
    Abstract: The invention relates to methods and apparatus for manufacturing intravascular stents wherein the intravascular stent has its inner surface treated to promote the migration of endothelial cells onto the inner surface of the intravascular stent. In particular, the inner surface of the intravascular stent has at least one groove formed therein.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: October 17, 2017
    Assignee: Vactronix Scientific, Inc.
    Inventors: Christopher E. Banas, Julio C. Palmaz, Eugene A. Sprague
  • IMPLANTABLE MEDICAL DEVICES HAVING CONTROLLED SURFACE PROPERTIES FOR IMPROVED HEALING RESPONSE
    Publication number: 20170258570
    Abstract: An implantable medical device that is fabricated from materials that present a blood or body fluid or tissue contact surface that has controlled heterogeneities in material constitution. An endoluminal stent-graft and web-stent that is made of a monolithic material formed into differentiated regions defining structural members and web regions extending across interstitial spaces between the structural members. The endoluminal stent-graft is characterized by having controlled heterogeneities at the blood flow surface of the stent.
    Type: Application
    Filed: May 30, 2017
    Publication date: September 14, 2017
    Inventors: Julio C. PALMAZ, Eugene A. SPRAGUE
  • Implantable medical devices having controlled surface properties for improved healing response
    Patent number: 9662230
    Abstract: An implantable medical device that is fabricated from materials that present a blood or body fluid or tissue contact surface that has controlled heterogeneities in material constitution. An endoluminal stent-graft and web-stent that is made of a monolithic material formed into differentiated regions defining structural members and web regions extending across interstitial spaces between the structural members. The endoluminal stent-graft is characterized by having controlled heterogeneities at a the blood flow surface of the stent.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: May 30, 2017
    Assignee: VACTRONIX SCIENTIFIC, INC.
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • IMPLANTABLE BIOMATERIALS HAVING ENGINEERED FUNCTIONAL SURFACES
    Publication number: 20170049937
    Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
    Type: Application
    Filed: July 25, 2016
    Publication date: February 23, 2017
    Inventors: Julio C. Palmaz, Eugene A. SPRAGUE
  • Implantable materials having engineered surfaces comprising a pattern of features and method of making same
    Patent number: 9399087
    Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: July 26, 2016
    Assignee: Advanced Bio Prosthetic Surfaces, Ltd., a wholly owned subsidiary of Palmaz Scientific, Inc.
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • Method for making grooves on a luminal surface of an intravascular stent
    Patent number: 8920660
    Abstract: Methods for manufacturing intravascular stents are disclosed wherein the intravascular stent has its inner surface treated to promote the migration of endothelial cells onto the inner surface of the intravascular stent. In particular, the inner surface of the intravascular stent has at least one groove formed therein.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: December 30, 2014
    Assignee: Advanced Bio Prosthetic Surfaces, Ltd., a wholly owned subsidiary of Palmaz Scientific Inc.
    Inventors: Christopher E. Banas, Julio C. Palmaz, Eugene A. Sprague
  • IMPLANTABLE MATERIALS HAVING ENGINEERED SURFACES COMPRISING A PATTERN OF FEATURES AND METHOD OF MAKING SAME
    Publication number: 20140314992
    Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
    Type: Application
    Filed: April 18, 2014
    Publication date: October 23, 2014
    Applicant: ADVANCED BIO PROSTHETIC SURFACES, LTD., a wholly owned subsidiary of Palmaz Scientific, Inc.
    Inventors: Julio C. PALMAZ, Eugene A. SPRAGUE