Patents by Inventor Eugene Barsov

Eugene Barsov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Retrovirus vectors derived from avian sarcoma leukosis viruses permitting transfer of genes into mammalian cells and therapeutic uses thereof
    Patent number: 6794188
    Abstract: Recombinant avian sarcoma leukosis virus (ASLV)-derived retrovirus vectors having an expanded host range are described. The host range is expanded by the replacement of the ASLV envelope gene by an envelope gene from a virus capable of infecting both mammalian and avian cells. The resulting recombinant ASLV-derived retroviral vectors can replicate efficiently in avian cells, infect both avian and mammalian cells in high titer, and are replication-defective in mammalian cells. Thus, they are quite safe and advantageous for use in gene therapy and vaccines.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: September 21, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Eugene Barsov, Stephen H. Hughes
  • Retrovirus vectors derived from avian sarcoma leukosis viruses permitting transfer of genes into mammalian cells and therapeutic uses thereof
    Publication number: 20020110896
    Abstract: Recombinant avian sarcoma leukosis virus (ASLV)-derived retrovirus vectors having an expanded host range are described. The host range is expanded by the replacement of the ASLV envelope gene by an envelope gene from a virus capable of infecting both mammalian and avian cells. The resulting recombinant ASLV-derived retroviral vectors can replicate efficiently in avian cells, infect both avian and mammalian cells in high titer, and are replication-defective in mammalian cells. Thus, they are quite safe and advantageous for use in gene therapy and vaccines.
    Type: Application
    Filed: September 24, 2001
    Publication date: August 15, 2002
    Inventors: Eugene Barsov, Stephen H. Hughes
  • Retrovirus vectors derived from avian sarcoma leukosis viruses permitting transfer of genes into mammalian cells
    Patent number: 6096534
    Abstract: Recombinant avian sarcoma leukosis virus (ASLV)-derived retrovirus vectors having an expanded host range are described. The host range is expanded by the replacement of the ASLV envelope gene by an envelope gene from a virus capable of infecting both mammalian and avian cells. The resulting recombinant ASLV-derived retroviral vectors can replicate efficiently in avian cells, infect both avian and mammalian cells in high titer, and are replication-defective in mammalian cells. Thus, they are quite safe and advantageous for use in gene therapy and vaccines.
    Type: Grant
    Filed: November 28, 1997
    Date of Patent: August 1, 2000
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Eugene Barsov, Stephen H. Hughes