Patents by Inventor Eugene Cha

Eugene Cha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tim-3 ligands and methods thereof
    Publication number: 20050191721
    Abstract: The invention relates to isolated polypeptides and nucleic acids encoding polypeptides which comprise a tim-3 IgV domain and a tim-3 intracellular domain, wherein the polypeptides do not comprise a tim-3 mucin domain or a tim-3 transmembrane domain. In addition, the invention relates to methods of modulating immune responses in a subject, comprising administering to the subject a therapeutically effective amount of an agent that modulates tim-3 activity. Immune responses include, but are not limited to, immune tolerance, transplantation tolerance, Th1 responses and Th2 responses.
    Type: Application
    Filed: October 4, 2004
    Publication date: September 1, 2005
    Applicants: Brigham and Women's Hospital, Beth Israel Deaconess Medical Center
    Inventors: Vijay Kuchroo, Terry Strom, Eugene Cha, Sumone Chakravarti, Catherine Sabatos, Chen Zhu, Xin Zheng, Alberto Sanchez-Fueyo