Patents by Inventor Eugene Davidson

Eugene Davidson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060286672
    Abstract: A catalytic conformational sensor method for detecting abnormal proteins and proteinaceous particles. The method is based on the interaction of a peptide fragment or probe with an abnormal proteinaceous particle. The interaction catalyzes transformation of the probe to a predominately beta sheet conformation and allows the probe to bind to the abnormal proteinaceous particle. This in turn, catalyzes propagation of a signal associated with the test sample-bound probe. As a result signals can be propagated even from samples containing very low concentrations of abnormal proteinaceous particles. The peptide probes can be designed to bind to a desired peptide sequence or can even be based on dendrimer structure to control further aggregate propagation.
    Type: Application
    Filed: May 30, 2002
    Publication date: December 21, 2006
    Inventors: Cindy Orser, Anne Grosset, Eugene Davidson
  • Publication number: 20060275910
    Abstract: A catalytic conformational sensor method for detecting abnormal proteins and proteinaceous particles. The method is based on the interaction of a peptide fragment or probe with an abnormal proteinaceous particle. The interaction catalyzes transformation of the probe to a predominately beta sheet conformation and allows the probe to bind to the abnormal proteinaceous particle. This in turn, catalyzes propagation of a signal associated with the test sample-bound probe. As a result signals can be propagated even from samples containing very low concentrations of abnormal proteinaceous particles as is the case in many body-fluid derived samples.
    Type: Application
    Filed: August 16, 2006
    Publication date: December 7, 2006
    Inventors: Cindy Orser, Anne Grosset, Eugene Davidson
  • Publication number: 20050026165
    Abstract: The invention provides methods and kits for detecting conformationally altered proteins and prions in a sample. In one embodiment, the conformationally altered proteins and prions are associated with amyloidogenic diseases.
    Type: Application
    Filed: December 4, 2003
    Publication date: February 3, 2005
    Inventors: Cindy Orser, Anne Grosset, Eugene Davidson
  • Patent number: D391546
    Type: Grant
    Filed: July 22, 1997
    Date of Patent: March 3, 1998
    Inventors: Thomas H. Frink, Darrin Eugene Davidson