Patents by Inventor Eugene deJuan
Eugene deJuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8486052Abstract: A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient.Type: GrantFiled: December 27, 2010Date of Patent: July 16, 2013Assignee: The Johns Hopkins University School of MedicineInventors: Signe Erickson Varner, Eugene Dejuan, Aaron Christopher Barnes, Terry Harrison Shelley, Michael J. Cooney
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Patent number: 8454582Abstract: Featured is a method for instilling one or more bioactive agents into ocular tissue within an eye of a patient for the treatment of an ocular condition, the method comprising concurrently using at least two of the following bioactive agent delivery methods (A)-(C): (A) implanting a sustained release delivery device comprising one or more bioactive agents in a posterior region of the eye so that it delivers the one or more bioactive agents into the vitreous humor of the eye; (B) instilling (e.g., injecting or implanting) one or more bioactive agents subretinally; and (C) instilling (e.g., injecting or delivering by ocular iontophoresis) one or more bioactive agents into the vitreous humor of the eye.Type: GrantFiled: December 29, 2010Date of Patent: June 4, 2013Assignee: Surmodics, Inc.Inventors: Eugene deJuan, Signe E. Varner, Laurie R. Lawin
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Patent number: 8365721Abstract: A method for performing intraocular brachytherapy and an apparatus for performing the same is disclosed. The apparatus preferably comprises a hand-held delivery device that advances a radiation source into an associated cannula or probe that is positioned adjacent the target tissue. The handpiece provides for shielded storage of the radiation source when retracted from the cannula and includes a slider mechanism for advancing and retracting the radiation source. The radiation source is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end. A positioning system for the cannula is also disclosed.Type: GrantFiled: August 27, 2010Date of Patent: February 5, 2013Assignee: NeoVista Inc.Inventors: Charles E. Larsen, Richard A. Hillstead, Roelof Trip, Eugene deJuan, Mark S. Humayun, Eberhard Fritz, Rainer Pintaske, Sabine Willenkamp, Gerd T. Phillipps
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Publication number: 20120095278Abstract: A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).Type: ApplicationFiled: December 23, 2011Publication date: April 19, 2012Inventors: Eugene DeJuan, JR., Paul Hallen
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Patent number: 8100818Abstract: A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).Type: GrantFiled: July 19, 2007Date of Patent: January 24, 2012Assignee: TDH Partners, Inc.Inventors: Eugene DeJuan, Jr., Paul Hallen
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Patent number: 8096972Abstract: A therapeutic agent delivery device that is particularly suitable for delivery of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. Preferred devices of the invention are minimally invasive, refillable and may be easily fixed to the treatment area. Preferred delivery devices of the invention also include those that comprise a non-linear shaped body member housing one or more substances and a delivery mechanism for the sustained delivery of the one or more substances from the non-linear shaped body member to the patient.Type: GrantFiled: December 19, 2003Date of Patent: January 17, 2012Assignee: Johns Hopkins UniversityInventors: Sign Erickson Varner, Eugene Dejuan, Jr., Terry Shelley, Aaron Christopher Barnes, Mark Humayun
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Publication number: 20110159073Abstract: Featured is a method for instilling one or more bioactive agents into ocular tissue within an eye of a patient for the treatment of an ocular condition, the method comprising concurrently using at least two of the following bioactive agent delivery methods (A)-(C): (A) implanting a sustained release delivery device comprising one or more bioactive agents in a posterior region of the eye so that it delivers the one or more bioactive agents into the vitreous humor of the eye; (B) instilling (e.g., injecting or implanting) one or more bioactive agents subretinally; and (C) instilling (e.g., injecting or delivering by ocular iontophoresis) one or more bioactive agents into the vitreous humor of the eye.Type: ApplicationFiled: December 29, 2010Publication date: June 30, 2011Inventors: Eugene deJuan, Signe E. Varner, Laurie R. Lawin
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Publication number: 20110098686Abstract: A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient.Type: ApplicationFiled: December 27, 2010Publication date: April 28, 2011Applicant: Johns Hopkins UniversityInventors: Signe Erickson Varner, Eugene Dejuan, Aaron Christopher Barnes, Terry Harrison Shelley, Michael J. Cooney
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Patent number: 7883717Abstract: A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient.Type: GrantFiled: June 12, 2002Date of Patent: February 8, 2011Assignee: Johns Hopkins UniversityInventors: Signe Erickson Varner, Eugene Dejuan, Aaron Christopher Barnes, Terry Harrison Shelley, Michael J. Cooney
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Publication number: 20110004045Abstract: A method for performing intraocular brachytherapy and an apparatus for performing the same is disclosed. The apparatus preferably comprises a hand-held delivery device that advances a radiation source into an associated cannula or probe that is positioned adjacent the target tissue. The handpiece provides for shielded storage of the radiation source when retracted from the cannula and includes a slider mechanism for advancing and retracting the radiation source. The radiation source is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end. A positioning system for the cannula is also disclosed.Type: ApplicationFiled: August 27, 2010Publication date: January 6, 2011Inventors: Charles E. Larsen, Richard A. Hillstead, Roelof Trip, Eugene deJuan, Mark S. Humayun, Eberhard Fritz, Rainer Pintaske, Sabine Willenkamp, Gerd T. Phillipps
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Publication number: 20100268013Abstract: A method for performing intraocular brachytherapy and an apparatus for performing the same is disclosed. The apparatus preferably comprises a hand-held delivery device that advances a radiation source into an associated cannula or probe that is positioned adjacent the target tissue. The handpiece provides for shielded storage of the radiation source when retracted from the cannula and includes a slider mechanism for advancing and retracting the radiation source. The radiation source is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end. A positioning system for the cannula is also disclosed.Type: ApplicationFiled: June 2, 2010Publication date: October 21, 2010Inventors: Charles E. Larsen, Richard A. Hillstead, Roelof Trip, Eugene deJuan, Mark Humayun, Eberhard Fritz, Rainer Pintaske
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Patent number: 7803102Abstract: A method for performing intraocular brachytherapy and an apparatus for performing the same is disclosed. The apparatus preferably comprises a hand-held delivery device that advances a radiation source into an associated cannula or probe that is positioned adjacent the target tissue. The handpiece provides for shielded storage of the radiation source when retracted from the cannula and includes a slider mechanism for advancing and retracting the radiation source. The radiation source is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end. A positioning system for the cannula is also disclosed.Type: GrantFiled: November 7, 2006Date of Patent: September 28, 2010Assignee: NeoVista, Inc.Inventors: Charles E. Larsen, Richard A. Hillstead, Roelof Trip, Eugene deJuan, Mark S. Humayun, Eberhard Fritz, Rainer Pintaske, Sabine Willenkamp, Gerd T. Phillipps
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Patent number: 7563222Abstract: A method for performing intraocular brachytherapy and an apparatus for performing the same is disclosed. The apparatus preferably comprises a hand-held delivery device that advances a radiation source into an associated cannula or probe that is positioned adjacent the target tissue. The handpiece provides for shielded storage of the radiation source when retracted from the cannula and includes a slider mechanism for advancing and retracting the radiation source. The radiation source is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end.Type: GrantFiled: September 15, 2005Date of Patent: July 21, 2009Assignee: NeoVista, Inc.Inventors: Charles E. Larsen, Richard A. Hillstead, Roelof Trip, Eugene deJuan, Mark Humayun, Eberhard Fritz, Rainer Pintaske
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Patent number: 7485113Abstract: Devices and devices for the treatment of the eye are disclosed. Preferred devices of the invention include a piercing member that is inserted into the eye to create a pathway for a cannula. The cannula is slidably mounted to the piercing member and is adapted to reach a treatment site within the eye at which material is injected into and/or withdrawn from the eye. The outer diameter of the piercing member is small enough to allow for self-sealing of the insertion site of the device upon the device's withdrawal therefrom. Also disclosed are methods for the utilizing the devices to treat the eye.Type: GrantFiled: June 22, 2001Date of Patent: February 3, 2009Assignee: Johns Hopkins UniversityInventors: Signe Erickson Varner, Eugene Dejuan, Jr., Terry Harrison Shelley
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Publication number: 20080154204Abstract: Devices and methods for the treatment of the eye are disclosed. Preferred devices of the invention include a piercing member that is inserted into the eye to create a pathway for a cannula. The cannula is slidably mounted to the piercing member and is adapted to reach a treatment site within the eye at which material is injected into and/or withdrawn from the eye. The outer diameter of the piercing member is small enough to allow for self-sealing of the insertion site of the device upon the device's withdrawal therefrom. Also disclosed are methods for the utilizing the devices to treat the eye.Type: ApplicationFiled: February 27, 2008Publication date: June 26, 2008Applicant: The Johns Hopkins UniversityInventors: Signe Erickson Varner, Eugene DeJuan, Terry Harrison Shelley
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Publication number: 20070265485Abstract: A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).Type: ApplicationFiled: July 19, 2007Publication date: November 15, 2007Inventors: Eugene DeJuan, Paul Hallen
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Patent number: 7276019Abstract: A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).Type: GrantFiled: March 8, 2005Date of Patent: October 2, 2007Assignee: RetinaLabs, Inc.Inventors: Eugene DeJuan, Jr., Paul Hallen
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Patent number: 7223225Abstract: A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).Type: GrantFiled: November 18, 2005Date of Patent: May 29, 2007Assignee: RetinaLabs, Inc.Inventors: Eugene DeJuan, Jr., Paul Hallen
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Patent number: 7220225Abstract: A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).Type: GrantFiled: April 20, 2006Date of Patent: May 22, 2007Assignee: RetinaLabs, Inc.Inventors: Eugene Dejuan, Jr., Paul Hallen
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Patent number: 7217263Abstract: A microcatheter system that allows for vascular infusion into retinal veins for extended periods of time. The microcatheter system includes a flexible cannula that is inserted into the retinal vein lumen and that remains stably within the retinal vein lumen without being held by a robot, micromanipulator or similar holding devices. The microcatheter system is particularly suitable for the treatment of retinal venous occlusive disease.Type: GrantFiled: January 3, 2001Date of Patent: May 15, 2007Assignee: The Johns Hopkins UniversityInventors: Mark S. Humayun, Patrick S. Jensen, Terry H. Shelley, Gildo Y. Fujii, Hany S. Hamza, Aaron C. Barnes, Eugene deJuan, Jr.