Abstract: An aspirator/nebulizer for use in inhalation therapy has dual oxygen nozzles extending into a cylindrical chamber into which air can be aspirated in a controlled manner via closable air holes. A 50 psig oxygen source can be diluted to atmospheric air to yield an oxygen/air mixture comprising less than 30% oxygen at the conventional patient flow rates of 30-60 liters per minute. The dual oxygen nozzles also allow pure oxygen to be delivered at rates of at least 40 liters per minute when such high flow rates of relatively pure oxygen are needed for short term therapy.

Abstract: A container with a centrally located, integrally formed non-coring and non-leaking piercing site for use with sterile instruments. A double dome construction is employed to permit needle penetration without coring by the needle and provide sealing between the container and the needle. Provision is also made to insure sealing when a larger diameter plastic needle is employed. In another embodiment there is provided a container with a non-coring piercing site and a separate sealing cover.

Abstract: Sterile solution delivery and venting devices for use with multi-dose sterile solution packages are disclosed. The devices include a positive acting, normally closed check valve which opens to express solution from the package when squeezing pressure is applied and which automatically closes when the pressure is released. A hydrophobic filter is included to sterilize the replacement air which enters the package upon release of the squeezing pressure.

Abstract: A container with integrally formed non-coring and non-leaking piercing site for use with sterile instruments. A double dome construction is employed to permit needle penetration without coring of the needle and provide sealing between the container and the needle. Provision is also made to insure sealing when a larger diameter plastic needle is employed.

Abstract: A single use vial is provided in clusters of five or two times five separably joined vials. The vials are molded and filled with a medicated or non-medicated solution and each vial is provided with a converging, planar front wall. The vials include an integral dispensing nozzle, having a conduit which can be exposed by removing a twist off closure. A common separation strip joins the facing side of adjacent vials in the cluster but not the twist off closures. The angle of convergence of the front wall is designed to elevate the conduit above the solution level when the front wall is placed upon a horizontal surface to prevent unwanted dripping prior to use.

Abstract: Humidifier and nebulizer adapter heads and humidifier assembly for inhalation therapy wherein high moisture content can be provided in a gas stream at high flow rates. The humidifier assembly consists of a disposable bottle and the disposable humidifier adapter head. The adapter head employs a conventional nebulizer to create a dense aerosol of sterile water and/or medicament entrained in an oxygen/air stream. The stream passes through a labyrinth of wide baffles which forces the stream to take a tortuous path resulting in turbulent flow and a high removal of droplets from the gas stream, but without generating a significant back pressure. The large surface area deflectors of the labyrinth also allow higher humidity of the gas stream due to evaporation. Water removed from the gas stream drains directly to the bottle.

Abstract: This invention relates to a single use container package especially adapted for use as a pharmaceutical delivery system. It is a two unit package comprising a liquid containing bottle and an open ended pharmaceutical capsule.

Abstract: A prefilled syringe having a barrel to hold a liquid medium is disclosed. The rear end of the barrel is sealed by means of a rubber diaphragm whereas the front end of the syringe is sealed by a stopper and a novel needle hub assembly whereby the integrity of the liquid medium remains static until the assembly is activated and the stopper pierced.