Patents by Inventor Eugene J. Vater

Eugene J. Vater has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and intermediates for the preparation of (1,2,5)-6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylates or salts thereof
    Patent number: 7728165
    Abstract: In one embodiment, the present application relates to a process of making a compound of formula I. and to certain intermediate compounds that are made within the process of making the compound of formula I.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: June 1, 2010
    Assignee: Schering Plough Corporation
    Inventors: Jeonghan Park, Anantha R Sudhakar, George S. K. Wong, Minzhang Chen, Juergen Weber, Xiaojing Yang, Daw-long Kwok, Ingyu Jeon, Ramani R Raghavan, Maria Tamarez, Weidong Tong, Eugene J. Vater
  • PREPARATION OF 3-AMINO-3-(CYCLOBUTYLMETHYL)-2-(HYDROXY)-PROPIONAMIDE HYDROCHLORIDE
    Publication number: 20100113821
    Abstract: Disclosed is a process for preparing 3-(amino)-3-cyclobutylmethyl-2-hydroxy-propionamide hydrochloride, an intermediate useful in the preparation of the HCV protease inhibitor (1R,5S)—N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide.
    Type: Application
    Filed: December 17, 2007
    Publication date: May 6, 2010
    Applicant: Schering-Plough Corporation
    Inventors: Jeonghan Park, Eugene J. Vater, Shuan Dong, Tetsuo Iwama, Ramani R. Raghavan, Hong-Chang Lee, George S.k. Wong
  • PROCESS AND INTERMEDIATES FOR THE PREPARATION OF (1R,2S,5S)-6,6-DIMETHYL-3-AZABICYCLO[3,1,0]HEXANE-2-CARBOXYLATES OR SALTS THEREOF
    Publication number: 20090247784
    Abstract: In one embodiment, the present application relates to a process of making a compound of formula I. and to certain intermediate compounds that are made within the process of making the compound of formula I.
    Type: Application
    Filed: June 15, 2009
    Publication date: October 1, 2009
    Inventors: Jeonghan Park, Anantha R. Sudhakar, George S. Wong, Minzhang Chen, Juergen Weber, Xiaojing Yang, Daw-Jong Kwok, Ingyu Jeon, Ramani R. Raghavan, Maria Tamarez, Weidong Tong, Eugene J. Vater
  • Process and intermediates for the preparation of (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylates for salts thereof
    Patent number: 7569705
    Abstract: In one embodiment, the present application relates to a process of making a compound of formula I. and to certain intermediate compounds that are made within the process of making the compound of formula I.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: August 4, 2009
    Assignee: Schering Corporation
    Inventors: Jeonghan Park, Anantha R Sudhakar, George S. K. Wong, Minzhang Chen, Juergen Weber, Xiaojing Yang, Daw-long Kwok, Ingyu Jeon, Ramani R Raghavan, Maria Tamarez, Weidong Tong, Eugene J. Vater
  • Process and intermediates for the preparation of (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylates or salts thereof
    Patent number: 7309717
    Abstract: In one embodiment, the present application relates to a process of making a compound of formula I. and to certain intermediate compounds that are made within the process of making the compound of formula I.
    Type: Grant
    Filed: June 15, 2004
    Date of Patent: December 18, 2007
    Assignee: Schering Corporation
    Inventors: Jeonghan Park, Anantha Sudhakar, George S. Wong, Minzhang Chen, Juergen Weber, Xiaojing Yang, Daw-Jong Kwok, Ingyu Jeon, Ramani R. Raghavan, Maria Tamarez, Weidong Tong, Eugene J. Vater
  • Enantioselective synthesis
    Patent number: 6262270
    Abstract: A short practical commercial process for the efficient enantioselective synthesis of the non-steroidal antiestrogen of formula I or XIV or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 11, 1999
    Date of Patent: July 17, 2001
    Assignee: Schering Corporation
    Inventors: Richard W. Draper, Radha V. Iyer, Yuelie Lu, Eugene J. Vater
  • Process for preparation of 9.alpha. -chloro-11.beta. formyloxypregna-3.20-diones
    Patent number: 5670676
    Abstract: Disclosed is a process for producing a compound of the formula: ##STR1## by reacting a compound of the formula: ##STR2## with: (1) a chlorinating reagent selected from an N-chloroimide or an N-chloroamide; (2) an anhydrous strong acid selected from orthophosphoric acid, alkylsulfonic acids, fluoroalkylsulfonic acids or arylsulfonic acids; and (3) anhydrous dimethylformamide; at a temperature within the range of about -78.degree. to about 0.degree. C.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: September 23, 1997
    Assignee: Schering Corporation
    Inventors: Richard W. Draper, Eugene J. Vater
  • Process for preparation of 9.alpha.-chloro-11.beta.-formyloxypregna-3,20-diones
    Patent number: 5602248
    Abstract: Disclosed is a process for producing a compound of the formula: ##STR1## by reacting a compound of the formula: ##STR2## with: (1) a chlorinating reagent selected from an N-chloroimide or an N-chloroamide; (2) an anhydrous strong acid selected from orthophosphoric acid, alkylsulfonic acids, fluoroalkylsulfonic acids or arylsulfonic acids; and (3) anhydrous dimethyl formamide; at a temperature within the range of about -78.degree. to about 0.degree. C., under anhydrous conditions under an inert atmosphere.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: February 11, 1997
    Assignee: Schering Corporation
    Inventors: Richard W. Draper, Eugene J. Vater