Patents by Inventor Eugene Medlock

Eugene Medlock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATMENT USING IL-17E ANTAGONISTS
    Publication number: 20140037635
    Abstract: Novel IL-17 like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing IL-17 like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with IL-17 like polypeptides, agonists, or antagonists thereof.
    Type: Application
    Filed: June 26, 2013
    Publication date: February 6, 2014
    Applicant: Amgen Inc.
    Inventors: Eugene MEDLOCK, Gary S. ELLIOTT, Shuqian JING, Scott Michael SILBIGER, Hung Q. NGUYEN, Richard YEH
  • Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
    Patent number: 8455629
    Abstract: Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: June 4, 2013
    Assignees: Amgen Inc., Medarex, Inc.
    Inventors: William J. Boyle, Eugene Medlock, John K. Sullivan, Robin L. Elliott, Frank Martin, Haichun Huang
  • Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
    Patent number: 8367063
    Abstract: Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: February 5, 2013
    Assignees: Amgen, Inc., Medarex, Inc.
    Inventors: William J. Boyle, Eugene Medlock, John K. Sullivan, Robin L. Elliott, Frank Martin, Haichun Huang
  • Human Anti-OPGL Neutralizing Antibodies As Selective OPGL Pathway Inhibitors
    Publication number: 20120156725
    Abstract: Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
    Type: Application
    Filed: January 27, 2012
    Publication date: June 21, 2012
    Applicants: MEDAREX, INC., AMGEN INC.
    Inventors: William J. Boyle, Eugene Medlock, John K. Sullivan, Robin L. Elliott, Frank Martin, Haichun Huang
  • IL-17 RECEPTOR LIKE MOLECULES AND USES THEREOF
    Publication number: 20110160438
    Abstract: The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Application
    Filed: October 28, 2010
    Publication date: June 30, 2011
    Applicant: Amgen Inc.
    Inventors: Eugene Medlock, Richard Yeh, Scott M. Silbiger, Gary S. Elliott, Hung Q. Nguyen, Shuqian Jing
  • IL-17 receptor like molecules and uses thereof
    Patent number: 7943738
    Abstract: The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: May 17, 2011
    Assignee: Amgen Inc.
    Inventors: Eugene Medlock, Richard Yeh, Scott Michael Sibiger, Gary S. Elliott, Hung Q. Nquyen, Shuqian Jing
  • Human Anti-OPGL Neutralizing Antibodies as Selective OPGL Pathway Inhibitors
    Publication number: 20110052604
    Abstract: Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
    Type: Application
    Filed: May 18, 2010
    Publication date: March 3, 2011
    Applicant: AMGEN, INC.
    Inventors: William J. Boyle, Eugene Medlock, John J. Sullivan, Robin L. Elliott, Frank Martin, Haichun Huang
  • METHODS OF TREATMENT USING IL-17E ANTAGONISTS
    Publication number: 20100303820
    Abstract: Novel IL-17 like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing IL-17 like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with IL-17 like polypeptides, agonists, or antagonists thereof.
    Type: Application
    Filed: May 25, 2010
    Publication date: December 2, 2010
    Applicant: Amgen Inc.
    Inventors: Eugene Medlock, Richard Yeh, Scott Michael Silbiger, Gary S. Elliott, Hung Q. Nguyen, Shuqian Jing
  • Human Anti-OPGL Neutralizing Antibodies As Selective OPGL Pathway Inhibitors
    Publication number: 20100209435
    Abstract: Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
    Type: Application
    Filed: February 15, 2010
    Publication date: August 19, 2010
    Applicants: AMGEN INC., MEDAREX, INC.
    Inventors: William J. Boyle, Eugene Medlock, John K. Sullivan, Robin L. Elliott, Frank Martin, Haichun Huang
  • Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
    Patent number: 7718776
    Abstract: Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
    Type: Grant
    Filed: April 7, 2003
    Date of Patent: May 18, 2010
    Assignees: Amgen Inc., Medarex, Inc.
    Inventors: William J. Boyle, Eugene Medlock, John J. Sullivan, Robin L. Elliott, Frank Martin, Haichun Huang
  • IL-17 receptor like molecules and uses thereof
    Publication number: 20090281287
    Abstract: The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Application
    Filed: June 3, 2009
    Publication date: November 12, 2009
    Applicant: Amgen Inc.
    Inventors: Eugene Medlock, Richard Yeh, Scott M. Silbiger, Gary S. Elliott, Hung Q. Nguyen, Shuqian Jing
  • IL-receptor like molecules and uses thereof
    Patent number: 7611857
    Abstract: The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: November 3, 2009
    Assignee: Amgen Inc.
    Inventors: Eugene Medlock, Richard Yeh, Scott Michael Silbiger, Gary S. Elliott, Hung Q. Nquyen, Shuqian Jing
  • IL-17 like molecules and uses thereof
    Publication number: 20070123459
    Abstract: Novel IL-17 like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing IL-17 like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with IL-17 like polypeptides, agonists, or antagonists thereof.
    Type: Application
    Filed: October 6, 2006
    Publication date: May 31, 2007
    Applicant: AMGEN INC.
    Inventors: Eugene Medlock, Richard Yeh, Scott Silbiger, Gary Elliott, Hung Nguyen, Shuqian Jing
  • IL-17 receptor like molecules and uses thereof
    Patent number: 7094566
    Abstract: The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: August 22, 2006
    Assignee: Amgen Inc.,
    Inventors: Eugene Medlock, Richard Yeh, Scott M. Silbiger, Gary S. Elliott, Hung Q. Nguyen, Shuqian Jing
  • IL-receptor like molecules and uses thereof
    Publication number: 20060078933
    Abstract: The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Application
    Filed: October 11, 2005
    Publication date: April 13, 2006
    Applicant: AMGEN INC.
    Inventors: Eugene Medlock, Richard Yeh, Scott Silbiger, Gary Elliott, Hung Nguyen, Shuqian Jing
  • IL-17 receptor like polypeptides and uses thereof
    Publication number: 20060078966
    Abstract: The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Application
    Filed: October 11, 2005
    Publication date: April 13, 2006
    Applicant: AMGEN INC.
    Inventors: Eugene Medlock, Richard Yeh, Scott Silbiger, Gary Elliott, Hung Nguyen, Shuqian Jing
  • Antibodies for IL-17 receptor like polypeptides and uses thereof
    Publication number: 20060078967
    Abstract: The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Application
    Filed: October 11, 2005
    Publication date: April 13, 2006
    Applicant: AMGEN INC.
    Inventors: Eugene Medlock, Richard Yeh, Scott Silbiger, Gary Elliott, Hung Nguyen, Shuqian Jing
  • IL-17 RECEPTOR LIKE MOLECULES AND USES THEREOF
    Publication number: 20050234221
    Abstract: Novel IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.
    Type: Application
    Filed: March 16, 2001
    Publication date: October 20, 2005
    Inventors: Eugene Medlock, Richard Yeh, Scott Silbiger, Gary Elliot, Hung Nguyen, Shuqian Jing
  • IL-17 like molecules and uses thereof
    Publication number: 20050074427
    Abstract: Novel IL-17 like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing IL-17 like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with IL-17 like polypeptides, agonists, or antagonists thereof.
    Type: Application
    Filed: May 27, 2004
    Publication date: April 7, 2005
    Inventors: Eugene Medlock, Richard Yeh, Scott Silbiger, Gary Elliott, Hung Nguyen, Shuqian Jing
  • Il-17 like molecules and uses thereof
    Publication number: 20050048029
    Abstract: Novel IL-17 like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing IL-17 like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with IL-17 like polypeptides, agonists, or antagonists thereof.
    Type: Application
    Filed: June 17, 2004
    Publication date: March 3, 2005
    Applicant: AMGEN, INC.
    Inventors: Eugene Medlock, Richard Yeh, Scott Silbiger, Gary Elliott, Hung Nguyen, Shuqian Jing