Patents by Inventor Eugene Zhukovsky

Eugene Zhukovsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific CD33 and CD3 Binding Proteins
    Publication number: 20160002333
    Abstract: Described herein are binding proteins that specifically bind to human CD33, and in particular to bispecific binding proteins that specifically bind to human CD33 and human CD3. Also described herein are bispecific tandem diabodies that bind to CD33 and CD33, and their uses for immunotherapy of CD33+ cancers, diseases and conditions such as acute myeloid leukemia (AML).
    Type: Application
    Filed: March 9, 2015
    Publication date: January 7, 2016
    Inventors: Kristina ELLWANGER, Luke EVNIN, Judith A. FOX, Ivica FUCEK, Jeanmarie GUENOT, Stefan KNACKMUSS, Lori KUNKEL, Melvyn LITTLE, Vera MOLKENTHIN, Erich RAJKOVIC, Uwe REUSCH, Claudia WALL, Michael WEICHEL, Eugene ZHUKOVSKY
  • Bispecific CD33 and CD3 binding proteins
    Patent number: 9212225
    Abstract: Described herein are binding proteins that specifically bind to human CD33, and in particular to bispecific binding proteins that specifically bind to human CD33 and human CD3. Also described herein are bispecific tandem diabodies that bind to CD33 and CD33, and their uses for immunotherapy of CD33+ cancers, diseases and conditions such as acute myeloid leukemia (AML).
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: December 15, 2015
    Assignee: AMPHIVENA THERAPEUTICS, INC.
    Inventors: Kristina Ellwanger, Luke Evnin, Judith A. Fox, Ivica Fucek, Jeanmarie Guenot, Stefan Knackmuss, Lori Kunkel, Melvyn Little, Vera Molkenthin, Erich Rajkovic, Uwe Reusch, Claudia Wall, Michael Weichel, Eugene Zhukovsky
  • Facility access management system
    Publication number: 20090271207
    Abstract: An enhanced delivery system (300) for field service providers is disclosed. In its simplest form, the delivery system (300), can comprise the steps of: granting (305) permission to a service provider to provide a designated service at an assigned location; traveling (310) to the assigned location to provide a service; remotely actuating (315) an access point to gain access to a restricted area; accessing (320) the restricted area through the access point; providing (325) a service in connection with the restricted area; and closing (330) the access point after accessing the restricted area. The system (300) facilitates and simplifies access to restricted areas, and contributes to routinizing the service process for enhanced efficiencies.
    Type: Application
    Filed: April 29, 2008
    Publication date: October 29, 2009
    Inventors: William P. Lanigan, Maciej Labowicz, David S. Schuman, Eugene Zhukovsky, John Wepfer, Gary A. Naese
  • BAFF variants and methods thereof
    Publication number: 20050130892
    Abstract: The invention relates to novel proteins with BAFF dominant negative antagonist, receptor antagonist activity and agonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of BAFF or APRIL-related disorders.
    Type: Application
    Filed: September 16, 2004
    Publication date: June 16, 2005
    Inventors: John Desjarlais, Adam Thomason, Eugene Zhukovsky, Seung Chu
  • Interferon variants with improved properties
    Publication number: 20050054053
    Abstract: The invention relates to interferon variants with improved properties and methods for their use.
    Type: Application
    Filed: March 30, 2004
    Publication date: March 10, 2005
    Inventors: Anna Aguinaldo, Amelia Beyna, Ho Cho, John Desjarlais, Shannon Marshall, Umesh Muchhal, Michael Villegas, Eugene Zhukovsky, Michael Quesenberry
  • BAFF variants and methods thereof
    Publication number: 20050048626
    Abstract: The invention relates to novel proteins with BAFF dominant negative antagonist, receptor antagonist activity and agonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of BAFF or APRIL-related disorders.
    Type: Application
    Filed: March 5, 2004
    Publication date: March 3, 2005
    Inventors: John Desjarlais, Adam Thomason, Eugene Zhukovsky
  • April variants and methods thereof
    Publication number: 20050003480
    Abstract: The invention relates to novel proteins of APRIL variants that modulate the biological activity as compared to naturally occurring APRIL or BAFF and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of BAFF or APRIL-related disorders.
    Type: Application
    Filed: March 31, 2004
    Publication date: January 6, 2005
    Inventors: John Desjarlais, Eugene Zhukovsky
  • Immediate early genes and methods of use therefor
    Publication number: 20040152658
    Abstract: The present invention provides methods and materials related to immediate early genes. Specifically, the invention provides isolated immediate early gene nucleic acid, cells that contain isolated immediate early gene nucleic acid, substantially pure polypeptides encoded by immediate early gene nucleic acid, and antibodies having specific binding affinity for a polypeptide encoded by immediate early gene nucleic acid. In addition, the invention provides cDNA libraries enriched for immediate early genes cDNAs, isolated nucleic acid derived from such cDNA libraries, and methods for treating conditions related to a deficiency in a neuron's immediate early gene responsiveness to a stimulus.
    Type: Application
    Filed: March 2, 2004
    Publication date: August 5, 2004
    Applicants: THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE, BASF-LYNX BIOSCIENCE AG, LYNX THERAPEUTICS, INC.
    Inventors: Paul F. Worley, Anthony Lanahan, Bernhard Goetz, Holger Hiemisch, Rohini Kuner, Sigrid Scheek, Karoly Nikolich, Eugene Zhukovsky
  • Interferon variants with improved properties
    Publication number: 20040137581
    Abstract: The invention relates to interferon variants with improved properties and methods for their use.
    Type: Application
    Filed: September 30, 2003
    Publication date: July 15, 2004
    Applicant: Xencor
    Inventors: Anna Marie Aguinaldo, Amelia Joy Beyna, Ho Sung Cho, John Rudolph Desjarlais, Shannon Alicia Marshall, Umesh Muchhal, Michael Francis Aquino Villegas, Eugene Zhukovsky
  • Immediate early genes and methods of use therefor
    Patent number: 6699660
    Abstract: The present invention provides methods and materials related to immediate early genes. Specifically, the invention provides isolated immediate early gene nucleic acid, cells that contain isolated immediate early gene nucleic acid, substantially pure polypeptides encoded by immediate early gene nucleic acid, and antibodies having specific binding affinity for a polypeptide encoded by immediate early gene nucleic acid. In addition, the invention provides cDNA libraries enriched for immediate early genes cDNAs, isolated nucleic acid derived from such cDNA libraries, and methods for treating conditions related to a deficiency in a neuron's immediate early gene responsiveness to a stimulus.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: March 2, 2004
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: Paul F. Worley, Anthony Lanahan, Bernhard Goetz, Holger Hiemisch, Rohini Kuner, Sigrid Scheek, Karoly Nikolich, Eugene Zhukovsky