Patents by Inventor Eugenia Njolito

Eugenia Njolito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of chiral beta amino acid derivatives by asymmetric hydrogenation
    Patent number: 7468459
    Abstract: The present invention relates to a process for the efficient preparation of enantiomerically enriched beta amino acid derivatives which are useful in the asymmetric synthesis of biologically active molecules. The process comprises an enantioselective hydrogenation of a prochiral beta amino acrylic acid derivative substrate in the presence of a transition metal precursor complexed with a chiral ferrocenyl diphosphine ligand.
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: December 23, 2008
    Assignee: Merck & Co., Inc.
    Inventors: Yi Xiao, Joseph D. Armstrong, III, Shane W. Krska, Eugenia Njolito, Nelo R. Rivera, Yongkui Sun, Thorsten Rosner
  • Process for the preparation of chiral beta amino acid derivatives by asymmetric hydrogenation
    Publication number: 20060194977
    Abstract: The present invention relates to a process for the efficient preparation of enantiomerically enriched beta amino acid derivatives which are useful in the asymmetric synthesis of biologically active molecules. The process comprises an enantioselective hydrogenation of a prochiral beta amino acrylic acid derivative substrate in the presence of a transition metal precursor complexed with a chiral ferrocenyl diphosphine ligand.
    Type: Application
    Filed: March 15, 2004
    Publication date: August 31, 2006
    Inventors: Yi Xiao, Joseph Armstrong III, Shane Krska, Eugenia Njolito, Nelo Rivera, Yongkui Sun, Thorsten Rosner