Patents by Inventor Eugenio C Petrella

Eugenio C Petrella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microplate thermal shift assay for ligand development using 5- (4"-dimethylaminophenyl) -2- (4' -phenyl) oxazole derivative fluorescent dyes
    Publication number: 20030175813
    Abstract: The present invention provides a method for ranking the affinity of each of a multiplicity of different molecules for a target molecule which is capable of unfolding due to a thermal change.
    Type: Application
    Filed: February 14, 2003
    Publication date: September 18, 2003
    Applicant: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Michael W. Pantoliano, Eugenio C. Petrella, F. Raymond Salemme, Barry A. Springer
  • Microplate thermal shift assay for ligand development using 5-(4?dimethylaminophenyl)-2-(4?-phenyl)oxazole derivative fluorescent dyes
    Patent number: 6569631
    Abstract: The present invention provides a method for ranking the affinity of each of a multiplicity of different molecules for a target molecule which is capable of unfolding due to a thermal change.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: May 27, 2003
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Michael W. Pantoliano, Eugenio C. Petrella, F. Raymond Salemme, Barry A. Springer
  • Method for identifying conditions that facilitate recombinant protein folding
    Patent number: 6291192
    Abstract: The present invention is a method for ranking the affinity of each of a multiplicity of different molecules for a target molecule which is capable of denaturing due to a thermal change.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: September 18, 2001
    Assignee: 3-Dimensional Pharmaceuticals Inc.
    Inventors: Michael W. Pantoliano, Eugenio C. Petrella, Francis R. Salemme, Barry A. Springer
  • Microplate thermal shift assay for ligand development and multi-variable protein chemistry optimization
    Patent number: 6291191
    Abstract: The present invention is a method for ranking the affinity of each of a multiplicity of different molecules for a target molecule which is capable of denaturing due to a thermal change.
    Type: Grant
    Filed: December 2, 1999
    Date of Patent: September 18, 2001
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Michael W. Pantoliano, Eugenio C. Petrella, Alexander W. Rhind, Francis R. Salemme, Barry A. Springer
  • Method for determining conditions that facilitate protein crystallization
    Patent number: 6268158
    Abstract: The present invention is a method for ranking the affinity of each of a multiplicity of different molecules for a target molecule which is capable of denaturing due to a thermal change.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: July 31, 2001
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Michael W. Pantoliano, Eugenio C. Petrella, Francis R. Salemme, Barry A. Springer
  • Method for determining conditions that stabilize proteins
    Patent number: 6232085
    Abstract: The present invention is a method for ranking the affinity of each of a multiplicity of different molecules for a target molecule which is capable of denaturing due to a thermal change.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: May 15, 2001
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Michael W Pantoliano, Eugenio C Petrella, Francis R Salemme, Barry A Springer