Patents by Inventor Eugenio Cingolani

Eugenio Cingolani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CDC-DERIVED EXOSOMES FOR TREATMENT OF VENTRICULAR TACHYARRYTHMIAS
    Publication number: 20220273729
    Abstract: Described herein are compositions and methods related to use of exosomes, including cardiosphere derived cell (CDC)-derived exosomes for treatment and prevention of heart related disease and conditions, such as ventral arrhythmias, such as tachycardias. CDC-derived exosomes delivered by endocardial injection can diminish the total amount of isolated late potentials associated with an isthmus of slow conduction, while reducing the isoelectric interval between late abnormal ventricular activity and decreasing the incidence of inducible ventricular arrhythmias, thereby providing a biological treatment for arrhythmias which otherwise requires therapeutic interventions with adverse effects.
    Type: Application
    Filed: May 19, 2022
    Publication date: September 1, 2022
    Inventors: Eduardo Marban, Eugenio Cingolani, James Dawkins
  • CDC-derived exosomes for treatment of ventricular tachyarrythmias
    Patent number: 11351200
    Abstract: Described herein are compositions and methods related to use of exosomes, including cardiosphere derived cell (CDC)-derived exosomes for treatment and prevention of heart related disease and conditions, such as ventral arrhythmias, such as tachycardias. CDC-derived exosomes delivered by endocardial injection can diminish the total amount of isolated late potentials associated with an isthmus of slow conduction, while reducing the isoelectric interval between late abnormal ventricular activity and decreasing the incidence of inducible ventricular arrhythmias, thereby providing a biological treatment for arrhythmias which otherwise requires therapeutic interventions with adverse effects.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: June 7, 2022
    Assignee: Cedars-Sinai Medical Center
    Inventors: Eduardo Marban, Eugenio Cingolani, James Dawkins
  • CDC-DERIVED EXOSOMES FOR TREATMENT OF VENTRICULAR TACHYARRYTHMIAS
    Publication number: 20190160111
    Abstract: Described herein are compositions and methods related to use of exosomes, including cardiosphere derived cell (CDC)-derived exosomes for treatment and prevention of heart related disease and conditions, such as ventral arrhythmias, such as tachycardias. CDC-derived exosomes delivered by endocardial injection can diminish the total amount of isolated late potentials associated with an isthmus of slow conduction, while reducing the isoelectric interval between late abnormal ventricular activity and decreasing the incidence of inducible ventricular arrhythmias, thereby providing a biological treatment for arrhythmias which otherwise requires therapeutic interventions with adverse effects.
    Type: Application
    Filed: June 2, 2017
    Publication date: May 30, 2019
    Applicant: Cedars-Sinai Medical Center
    Inventors: Eduardo Marban, Eugenio Cingolani, James Dawkins