Patents by Inventor Eui Cheol CHO

Eui Cheol CHO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12098209
    Abstract: An asymmetric fusion protein in which a fragment of an antibody binding to an insulin receptor, an iduronate-2-sulfatase (IDS) enzyme, and an Fc region are fused, and a use thereof are disclosed. The fusion protein can cross the blood-brain barrier (BBB) to deliver the IDS enzyme to the brain. Therefore, a pharmaceutical composition containing the fusion protein as an active ingredient can be used as a therapeutic agent for a central nervous system disease and particularly, is expected to prevent and treat various diseases caused by ribosome accumulation.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: September 24, 2024
    Assignee: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Ki Joon Cho, Mijung Lee, Eun Jung Song, Ki Su Kim, Kwan Yub Kang, Eui Cheol Cho
  • Publication number: 20210324094
    Abstract: An asymmetric fusion protein in which a fragment of an antibody binding to an insulin receptor, an iduronate-2-sulfatase (IDS) enzyme, and an Fc region are fused, and a use thereof are disclosed. The fusion protein can cross the blood-brain barrier (BBB) to deliver the IDS enzyme to the brain. Therefore, a pharmaceutical composition containing the fusion protein as an active ingredient can be used as a therapeutic agent for a central nervous system disease and particularly, is expected to prevent and treat various diseases caused by ribosome accumulation.
    Type: Application
    Filed: October 18, 2019
    Publication date: October 21, 2021
    Applicant: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Ki Joon CHO, Mijung LEE, Eun Jung SONG, Ki Su KIM, Kwan Yub KANG, Eui Cheol CHO