Patents by Inventor Eui Chul LEE
Eui Chul LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11713308Abstract: The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The 3,3-difluoroallylamines or their pharmaceutically acceptable salts exhibit potent inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).Type: GrantFiled: July 6, 2021Date of Patent: August 1, 2023Assignee: YUHAN CORPORATIONInventors: Tae Dong Han, Hee Jae Tak, Eun Kyung Kim, Eui Chul Lee, Sol Park, Hyok Jun Cho, Cheol Hee Lim, So Young Kim, Hyun Ho Choi, Da Na Jeong, Na Yeon Yang, Na Ry Ha
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Publication number: 20230044255Abstract: The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The 3,3-difluoroallylamines or their pharmaceutically acceptable salts exhibit potent inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).Type: ApplicationFiled: July 6, 2021Publication date: February 9, 2023Inventors: Tae Dong HAN, Hee Jae TAK, Eun Kyung KIM, Eui Chul LEE, Sol PARK, Hyok Jun CHO, Cheol Hee LIM, So Young KIM, Hyun Ho CHOI, Da Na JEONG, Na Yeon YANG, Na Ry HA
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Publication number: 20230002379Abstract: Provided are a compound having a 2,3-dihydro-1H-indene or 2,3-dihydrobenzofuran moiety or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same and a use thereof, where the compound having a 2,3-dihydro-1H-indene or 2,3-dihydrobenzofuran moiety or pharmaceutically acceptable salt thereof has an inhibitory activity against glucosylceramide synthase (GCS), and therefore can be usefully applied for preventing or treating various diseases associated with GCS, such as Gaucher disease, Fabry disease, Tay-Sachs disease, Parkinson's disease, etc.Type: ApplicationFiled: November 12, 2020Publication date: January 5, 2023Applicants: YUHAN CORPORATION, GREEN CROSS CORPORATIONInventors: Dong-Hoon KIM, Jae-Eun JOO, Eui-Chul LEE, Tae-Dong HAN, Seung-Yub SHIN, Sool-Ki KWON, Ji-Hye KIM
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Publication number: 20230002380Abstract: Provided are a compound having a chromane, isochromane, thiochromane, or tetrahydroquinoline moiety or pharmaceutically acceptable salt thereof, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof, wherein the compound having a chromane, isochromane, thiochromane, or tetrahydroquinoline moiety or pharmaceutically acceptable salt thereof has an inhibitory activity against glucosylceramide synthase (GCS), and therefore can be usefully applied for preventing or treating various diseases associated with GCS, such as Gaucher disease, Fabry disease, Tay-Sachs disease, Parkinson's disease, etc.Type: ApplicationFiled: November 12, 2020Publication date: January 5, 2023Applicants: YUHAN CORPORATION, GREEN CROSS CORPORATIONInventors: Dong-Hoon KIM, Jae-Eun JOO, Eui-Chul LEE, Tae-Dong HAN, Seung-Yub SHIN, Sool-Ki KWON
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Publication number: 20220402909Abstract: Provided are a compound having a 1,2,3,4-tetrahydronaphthalene moiety or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same and a use thereof, where the compound having a 1,2,3,4-tetrahydronaphthalene moiety or pharmaceutically acceptable salt thereof has an inhibitory activity against glucosylceramide synthase (GCS), and therefore can be usefully applied for preventing or treating various diseases associated with GCS, such as Gaucher disease, Fabry disease, Tay-Sachs disease, Parkinson's disease, etc.Type: ApplicationFiled: November 12, 2020Publication date: December 22, 2022Applicants: YUHAN CORPORATION, GREEN CROSS CORPORATIONInventors: Dong-Hoon KIM, Jae-Eun JOO, Eui-Chul LEE, Tae-Dong HAN, Seung-Yub SHIN, Sool-Ki KWON, Young-Gyu KONG, Sang-Ho MA, Ick-Hwan SON
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Publication number: 20220157332Abstract: This application relates to a device and a method for voice-based trauma screening using deep learning. The device and method for voice-based trauma screening using deep learning screen for trauma through voices that may be obtained in a non-contact manner without limitations of space or situation. In one aspect, the device includes a memory configured to store at least one program and a processor configured to perform an operation by executing the at least one program. The processor can obtain voice data, pre-process the voice data, convert pre-processed voice data into image data, and input the image data to a deep learning model and obtain a trauma result value as an output value of the deep learning model.Type: ApplicationFiled: November 16, 2021Publication date: May 19, 2022Inventors: Yoo Hun NOH, Eui Chul LEE, Na Hye KIM, So Eui KIM, Ji Won MOK, Su Gyeong YU, Na Yeon HAN
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Patent number: 11168073Abstract: The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The 3,3-difluoroallylamines or their pharmaceutically acceptable salts exhibit potent inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).Type: GrantFiled: December 12, 2019Date of Patent: November 9, 2021Assignee: YUHAN CORPORATIONInventors: Tae Dong Han, Hee Jae Tak, Eun Kyung Kim, Eui Chul Lee, Sol Park, Hyok Jun Cho, Cheol Hee Lim, So Young Kim, Hyun Ho Choi, Da Na Jeong, Na Yeon Yang, Na Ry Ha
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Publication number: 20210317110Abstract: The present technology provides triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g. for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).Type: ApplicationFiled: March 22, 2021Publication date: October 14, 2021Applicant: YUHAN CORPORATIONInventors: Tae Dong HAN, Hee Jae TAK, Eun Kyung KIM, Su Bin CHOI, Sol PARK, Dong Hoon KIM, So Young KIM, Hyun Ho CHOI, Tae Wang KIM, Mi Kyeong JU, Na Ry HA, Eui Chul LEE
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Patent number: 10995086Abstract: The present technology provides triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).Type: GrantFiled: March 20, 2019Date of Patent: May 4, 2021Assignee: Yuhan CorporationInventors: Tae Dong Han, Hee Jae Tak, Eun Kyung Kim, Su Bin Choi, Sol Park, Dong Hoon Kim, So Young Kim, Hyun Ho Choi, Tae Wang Kim, Mi Kyeong Ju, Na Ry Ha, Eui Chul Lee
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Patent number: 10941136Abstract: The present invention provides a quinazoline derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof. The quinazoline derivative or its pharmaceutically acceptable salt has a selective inhibitory activity against the phosphatidylinositol 3-kinase delta subunit, and therefore can be usefully applied for preventing or treating cancer, along with avoiding side effects such as lymphopenia-associated inflammatory responses.Type: GrantFiled: April 26, 2017Date of Patent: March 9, 2021Assignee: YUHAN CORPORATIONInventors: Young-Hwan Kim, Tae-Dong Han, Dong-Hoon Kim, Eun-Hye Jung, Su-Bin Choi, Eui-Chul Lee, Won-Ee Chong, Jin-Hwi Park, Jun-Chul Park, Ho-Woong Kang, Ji-Yeong Gal, Chan-Sun Park, Jong-Gyun Kim, Su-Youn Nam
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Publication number: 20200325120Abstract: The present invention provides a quinazoline derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof. The quinazoline derivative or its pharmaceutically acceptable salt has a selective inhibitory activity against the phosphatidylinositol 3-kinase delta subunit, and therefore can be usefully applied for preventing or treating cancer, along with avoiding side effects such as lymphopenia-associated inflammatory responses.Type: ApplicationFiled: April 26, 2017Publication date: October 15, 2020Applicant: YUHAN CORPORATIONInventors: Young-Hwan KIM, Tae-Dong HAN, Dong-Hoon KIM, Eun-Hye JUNG, Su-Bin CHOI, Eui-Chul LEE, Won-Ee CHONG, Jin-Hwi PARK, Jun-Chul PARK, Ho-Woong KANG, Ji-Yeong GAL, Chan-Sun PARK, Jong-Gyun KIM, Su-Youn NAM
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Publication number: 20200223827Abstract: The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The 3,3-difluoroallylamines or their pharmaceutically acceptable salts exhibit potent inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).Type: ApplicationFiled: December 12, 2019Publication date: July 16, 2020Inventors: Tae Dong HAN, Hee Jae TAK, Eun Kyung KIM, Eui Chul LEE, Sol PARK, Hyok Jun CHO, Cheol Hee LIM, So Young KIM, Hyun Ho CHOI, Da Na JEONG, Na Yeon YANG, Na Ry HA
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Publication number: 20190322655Abstract: The present technology provides triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).Type: ApplicationFiled: March 20, 2019Publication date: October 24, 2019Applicant: YUHAN CORPORATIONInventors: Tae Dong HAN, Hee Jae TAK, Eun Kyung KIM, Su Bin CHOI, Sol PARK, Dong Hoon KIM, So Young KIM, Hyun Ho CHOI, Tae Wang KIM, Mi Kyeong JU, Na Ry HA, Eui Chul LEE
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Patent number: 10383859Abstract: The present invention provides a benzo[d]thiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The benzo[d]thiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the benzo[d]thiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.Type: GrantFiled: July 6, 2017Date of Patent: August 20, 2019Assignee: Yuhan CorporationInventors: Se-Woong Oh, Youn Hur, Jin-Hwi Park, Jae-Eun Joo, Ho-Woong Kang, Hyok-Jun Cho, Eui-Chul Lee, Chan-Sun Park, Dong-Hyun Kim, Jong-Gyun Kim, Su-Youn Nam
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Publication number: 20190142809Abstract: The present invention provides a benzo[d]thiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The benzo[d]thiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the benzo[d]thiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.Type: ApplicationFiled: July 6, 2017Publication date: May 16, 2019Applicant: Yuhan CorporationInventors: Se-Woong Oh, Youn Hur, Jin-Hwi Park, Jae-Eun Joo, Ho-Woong Kang, Hyok-Jun Cho, Eui-Chul Lee, Chan-Sun Park, Dong-Hyun Kim, Jong-Gyun Kim, Su-Youn Nam
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Patent number: 8428323Abstract: A method of processing a blood vessel image is provided. The method includes (a) sharpening an original blood vessel image using a Gabor filter in consideration of various directions and thicknesses of blood vessels included in the blood vessel and (b) detecting edges according to a change in brightness in a blood vessel domain and a non-blood vessel domain of the original blood vessel image and the blood vessel image on which the Gabor filtering step is completed, using an edge extraction method based on a first-order differentiation or second-order differentiation.Type: GrantFiled: February 1, 2012Date of Patent: April 23, 2013Assignee: Dongguk University Industry-Academic Cooperation FoundationInventors: Sung Min Kim, Kwang Yong Shin, Young Ho Park, Hyeon Chang Lee, So Ra Cho, Eui Chul Lee, Gang Ryung Park
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Publication number: 20130028490Abstract: A method of processing a blood vessel image is provided. The method includes (a) sharpening an original blood vessel image using a Gabor filter in consideration of various directions and thicknesses of blood vessels included in the blood vessel and (b) detecting edges according to a change in brightness in a blood vessel domain and a non-blood vessel domain of the original blood vessel image and the blood vessel image on which the Gabor filtering step is completed, using an edge extraction method based on a first-order differentiation or second-order differentiation.Type: ApplicationFiled: February 1, 2012Publication date: January 31, 2013Applicant: Dongguk Univeristy, Industry-Academic Cooperation FoundationInventors: Sung Min Kim, Kwang Yong Shin, Young Ho Park, Hyeon Chang Lee, So Ra Cho, Eui Chul Lee, Gang Ryung Park
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Publication number: 20120308089Abstract: A method of biometric authentication based on unique information obtained from a pupil. The method includes: acquiring an image of a pupil and an iris; extracting a pupil region from the image; and generating unique biometric information by extracting a specific pattern of the pupil from the pupil region. The method performs biometric authentication by combining unique information obtained from a pupil region with unique information obtained from an iris region.Type: ApplicationFiled: September 22, 2011Publication date: December 6, 2012Applicant: KOREA BASIC SCIENCE INSTITUTEInventor: Eui Chul LEE
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Publication number: 20080137909Abstract: A gaze position tracking method and apparatus for simply mapping one's gaze position on a monitor screen are provided. The gaze position tracking apparatus includes an image capturing module, and an image processing module. The image capturing module illuminates infrared rays to a user's eyes, reflects an illuminated eye image at 45°, and captures the 45° reflected eye image. The image processing module obtains a pupil center point of the illuminated eye image by performing a predetermined algorithm, and maps the pupil center point on a display plane of a display device through a predetermined transform function.Type: ApplicationFiled: December 6, 2007Publication date: June 12, 2008Applicant: Electronics and Telecommunications Research InstituteInventors: Jaeseon LEE, Young Giu JUNG, Mun Sung HAN, Jun Seok PARK, Eui Chul LEE, Kang Ryoung PARK, Min Cheol HWANG, Joa Sang LIM, Yongjoo CHO