Patents by Inventor Eui-Ju Yeo

Eui-Ju Yeo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITION FOR PROMOTING THE HEALING OF WOUNDS AND CONTAINING LYSOPHOSPHATIDIC ACID AND AN ADENYLYL CYCLASE INHIBITOR AS ACTIVE INGREDIENTS
    Publication number: 20120083472
    Abstract: The present invention relates to a pharmaceutical composition for promoting the healing of wounds, containing lysophosphatidic acid and an adenylyl cyclase inhibitor as active ingredients, and more particularly, to a pharmaceutical composition which contains an adenylyl cyclase inhibitor and which promotes the healing of wounds in senescent cells or aged persons having physiological characteristics different than those of young cells or young persons. In addition, the present invention relates to a method for promoting the healing of wounds involving treating a wounded person with an effective dose of the lysophosphatidic acid and adenylyl cyclase inhibitor.
    Type: Application
    Filed: April 26, 2010
    Publication date: April 5, 2012
    Applicant: SNU R&DB FOUNDATION
    Inventors: Sang Chul Park, Eui Ju Yeo, Ji Heon Rhim
  • COMPOSITION FOR REGULATION CELLULAR SENESCENCE COMPRISING LYSOPHOSPHATIDIC ACID AND INHIBITOR OF ADENYLYL CYCLASE AS ACTIVE INGREDIENTS
    Publication number: 20110124607
    Abstract: The present invention relates to the molecular mechanism inducing cell proliferation in aged human fibroblasts by inhibiting AMPK using LPA and AC inhibitor. Particularly, the present invention relates to a composition comprising LPA and ACI as active ingredients and the invention proves with the said composition that LPA and ACI regulate different phosphorylation of AMPK? and thus inactivate p53 and induce senescent cell proliferation. This results support the fact that AMPK signal transduction plays an important role in cell proliferation of senescent cells.
    Type: Application
    Filed: May 14, 2008
    Publication date: May 26, 2011
    Inventors: Sang Chul Park, Eui Ju Yeo, Ji Heon Rhim
  • Signals and molecular species involved in senescence
    Patent number: 7482134
    Abstract: The present invention relates to (a) a method for detecting a senescent cell, which comprises measuring a relative alteration to young cell in a signal or molecular species involved in signal transduction; (b) a method; and (c) a composition for modulating cellular senescence comprising treating a senescent cell with the effective amount of an inhibitor of adenylyl cyclase or an inhibitor of protein kinase A.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: January 27, 2009
    Assignee: Seoul National University Industry Foundation
    Inventors: Ik-Soon Jang, Eui-Ju Yeo, Sang-Chul Park
  • Signals and molecular species involved in senescence
    Publication number: 20060099568
    Abstract: The present invention relates to (a) a method for detecting a senescent cell, which comprises measuring a relative alteration to young cell in a signal or molecular species involved in signal transduction; (b) a method; and (c) a composition for modulating cellular senescence comprising treating a senescent cell with the effective amount of an inhibitor of adenylyl cyclase or an inhibitor of protein kinase A.
    Type: Application
    Filed: June 5, 2002
    Publication date: May 11, 2006
    Inventors: Ik-Soon Jang, Eui-Ju Yeo, Sang-Chul Park