Patents by Inventor Eulogio Pimentel Vazquez
Eulogio Pimentel Vazquez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230405106Abstract: The present invention provides a chimeric protein that has a modular structure and comprises a receptor binding domain (RBD) from the spike protein (S) of coronaviruses, a segment able to bind the core antigen from the Hepatitis B Virus (HBcAg), a segment including six consecutive histidine residues (HHHHHH), and two spacer segments. In this chimeric protein the aforementioned segments are arranged in a specific order, and the protein is able to form hybrid nanoparticles with HBcAg. The chimeric protein is part of vaccine compositions used for the prevention of coronavirus infections. Therefore, the invention discloses a method for the prevention of coronavirus infections, whereby a vaccine composition comprising said chimeric protein is administered.Type: ApplicationFiled: November 3, 2021Publication date: December 21, 2023Inventors: Glay CHINEA SANTIAGO, Alejandro Miguel MARTÍN DUNN, Diamilé GONZÁLEZ ROCHE, Miladys LIMONTA FERNÁNDEZ, Enrique IGLESIAS PÉREZ, Mónica BEQUET ROMERO, Héctor SANTANA MILIAN, Gabriel J. MARQUEZ PERERA, Alexis MUSACCHIO LASA, Ania CABRALES RICO, Gerardo Enrique GUILLEN NIETO, Marta AYALA ÁVILA, Eulogio PIMENTEL VAZQUEZ, Gertrudis ROJAS DORANTES, Vivian HUERTA GALINDO
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Publication number: 20220168391Abstract: The present invention reveals the use of epidermal growth factor (EGF) for the manufacture of an injectable medicament for the treatment of a diabetic foot ulcer (DFU), in a patient without criteria of amputation of the affected limb at the time of the clinical evaluation, wherein the medicament comprising EGF is administered by intralesional infiltration in said ulcer once a week. Moreover, it provides a pharmaceutical composition comprising EGF, for the treatment of a DFU in a patient, where the composition is administered once a week. The invention comprises a method for the treatment of a DFU in a patient, without criteria of amputation of the affected limb at the time of the clinical evaluation, comprising administering EGF to the patient, by intralesional infiltration in the ulcer base once a week.Type: ApplicationFiled: March 16, 2020Publication date: June 2, 2022Inventors: Amaurys DEL RIO MARTIN, Hose Esteban SAURI CHAVEZ, Raimundo UBIETA GÓMEZ, Sonia GONZALEZ BLANCO, Jorge Amador BERLANGA ACOSTA, Verena Lucila MUZIO GONZÁLEZ, Eulogio PIMENTEL VÁZQUEZ
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Patent number: 11013235Abstract: The following invention discloses a method for the control of plant diseases wherein a composition comprising a compound having the structure represented by one of the formulas from I to V, is applied to the plants. It also discloses the use of said compounds, or their salts for the stimulation of the natural defense and the induction of resistance against plant diseases. Moreover, it comprises the use of said compounds of structure represented by one of the formulas from I to V for the preventive or curative treatment of said diseases. A composition for agriculture, comprising a compound having the structure represented by one of the formulas from I to V, is also part of the invention.Type: GrantFiled: January 24, 2020Date of Patent: May 25, 2021Assignee: Centro de Ingeniería Genética y BiotecnologíaInventors: Osmany Guirola Cruz, Orlando Borrás Hidalgo, Luis Javier González López, Raimundo Ubieta Gómez, Eulogio Pimentel Vázquez, Merardo Pujol Ferrer
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Patent number: 10993438Abstract: The following invention discloses a method for the control of plant diseases wherein a composition comprising a compound having the structure represented by one of the formulas from I to V, is applied to the plants. It also discloses the use of said compounds, or their salts for the stimulation of the natural defense and the induction of resistance against plant diseases. Moreover, it comprises the use of said compounds of structure represented by one of the formulas from I to V for the preventive or curative treatment of said diseases. A composition for agriculture, comprising a compound having the structure represented by one of the formulas from I to V, is also part of the invention.Type: GrantFiled: August 1, 2016Date of Patent: May 4, 2021Assignee: Centro de Ingeniería Genética y BiotecnologíaInventors: Osmany Guirola Cruz, Orlando Borrás Hidalgo, Luis Javier González López, Raimundo Ubieta Gómez, Eulogio Pimentel Vázquez, Merardo Pujol Ferrer
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Publication number: 20200288720Abstract: The following invention discloses a method for the control of plant diseases wherein a composition comprising a compound having the structure represented by one of the formulas from I to V, is applied to the plants. It also discloses the use of said compounds, or their salts for the stimulation of the natural defense and the induction of resistance against plant diseases. Moreover, it comprises the use of said compounds of structure represented by one of the formulas from I to V for the preventive or curative treatment of said diseases. A composition for agriculture, comprising a compound having the structure represented by one of the formulas from I to V, is also part of the invention.Type: ApplicationFiled: January 24, 2020Publication date: September 17, 2020Inventors: Osmany GUIROLA CRUZ, Orlando BORRÁS HIDALGO, Luis Javier GONZÁLEZ LÓPEZ, Raimundo UBIETA GÓMEZ, Eulogio PIMENTEL VÁZQUEZ, Merardo PUJOL FERRER
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Publication number: 20180213786Abstract: The following invention discloses a method for the control of plant diseases wherein a composition comprising a compound having the structure represented by one of the formulas from I to V, is applied to the plants. It also discloses the use of said compounds, or their salts for the stimulation of the natural defense and the induction of resistance against plant diseases. Moreover, it comprises the use of said compounds of structure represented by one of the formulas from I to V for the preventive or curative treatment of said diseases. A composition for agriculture, comprising a compound having the structure represented by one of the formulas from I to V, is also part of the invention.Type: ApplicationFiled: August 1, 2016Publication date: August 2, 2018Inventors: Osmany GUIROLA CRUZ, Orlando BORRÁS HIDALGO, Luis Javier GONZÁLEZ LÓPEZ, Raimundo UBIETA GÓMEZ, Eulogio PIMENTEL VÁZQUEZ, Merardo PUJOL FERRER
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Patent number: 9364524Abstract: A pharmaceutical composition using natural gonadotropin—releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting a faster and more potent immunological response against the endogenous GnRH hormone. This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers.Type: GrantFiled: March 19, 2015Date of Patent: June 14, 2016Assignee: CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIAInventors: Jesus Arturo Junco Barranco, Osvaldo Reyes Acosta, Eddy Emilio Bover Fuentes, Franklin Fuentes Aguilar, Eulogio Pimentel Vazquez, Roberto Basulto Baker, Gerardo Enrique Guillen Nieto, Yovisleidys Lopez Saez, Hilda Elisa Garay Perez, Lesvia Calzada Aguilera, Maria Castro Santana, Niurka Oneysi Arteaga More, Luis Alberto Aguero Barrocal
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Publication number: 20150190491Abstract: A pharmaceutical composition using natural gonadotropin—releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting a faster and more potent immunological response against the endogenous GnRH hormone. This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers.Type: ApplicationFiled: March 19, 2015Publication date: July 9, 2015Inventors: Jesus Arturo Junco Barranco, Osvaldo Reyes Acosta, Eddy Emilio Bover Fuentes, Franklin Fuentes Aguilar, Eulogio Pimentel Vazquez, Roberto Basulto Baker, Gerardo Enrique Guillen Nieto, Yovisleidys Lopez Saez, Hilda Elisa Garay Perez, Lesvia Calzada Aguilera, Maria Castro Santana, Niurka Oneysi Arteaga More, Luis Alberto Aguero Barrocal
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Patent number: 8999931Abstract: A pharmaceutical composition using natural gonadotropin-releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting a faster and more potent immunological response against the endogenous GnRH hormone. This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers.Type: GrantFiled: September 30, 2009Date of Patent: April 7, 2015Assignee: Centro de Ingenieria Genetica y BiotecnologiaInventors: Jesus Arturo Junco Barranco, Osvaldo Reyes Acosta, Eddy Emilio Bover Fuentes, Franklin Fuentes Aguilar, Eulogio Pimentel Vazquez, Roberto Basulto Baker, Gerardo Enrique Guillen Nieto, Yovisleidys Lopez Saez, Hilda Elisa Garay Perez, Lesvia Calzada Aguilera, Maria Castro Santana, Niurka Oneysi Arteaga More, Luis Alberto Aguero Barrocal
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Patent number: 8852601Abstract: The invention is related with the chemical synthesis for increase the growth rate in marketable fish and crustacean The aim of this invention is supply GHRP-6 to induce directly or indirectly the release of growthing hormone or like, to produce the increase of circulating growthing hormone level in the blood of the fishes. The peptide is stable, soluble and biologically active. The peptide is able to stimulate growth, improve the larvae quality, and increase the defense against pathogen agents, the dry weight, the protein concentration and the RNA in muscle of fish and crustaceans.Type: GrantFiled: January 22, 2003Date of Patent: October 7, 2014Assignee: Centro de Ingenieria Genetica y BiotecnologiaInventors: Mario Pablo Estrada Garcia, Rebeca Martinez Rodriguez, Amilcar Arenal Cruz, Rafael Marcos Pimentel Pérez, Antonio Morales Rojas, Eulogio Pimentel Vázquez, Alexander Espinosa Vázquez, Carmen Aday Garcia Molina, Edenaida Cabrera González, Mirta Vinjoy Campa, Sergio Toledo Pérez, Olimpia Carrillo Famés, Claudina Zaldivar Muñoz
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Patent number: 8268306Abstract: This invention relates to pesticide and antiparasitic compositions for the control of pests, diseases and parasites attacking plants and animals. The compositions include, at least one chitinolytic agent or a chitinolytic activity-inducing agent, and sulfide or a sulfide-producing agent from microorganisms or chemical compounds, wherein the chitinolytic agent or the chitinolytic activity-inducing agent and sulfur or a sulfur-producing agent obtaining from microorganisms or chemical compounds are concurrently applied at a range significantly lower than any of the above-mentioned compounds, when they are individually to attain effective control.Type: GrantFiled: August 16, 2010Date of Patent: September 18, 2012Assignee: Centro de Ingenieria Genetica y BiotecnologiaInventors: Jesus Mena Campos, Eulogio Pimentel Vazquez, Armando Tomas Hernadez Garcia, Liuven Veloz Gonzalez, Marieta Marin Bruzos, Oscar Compte Alberto, Marilin Domingo Puente, Licette Leon Barreras, Merardo Pujol Ferrero, Juan Diego Mencho Ponce, Carlos Borroto Nordelo
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Publication number: 20110250196Abstract: A pharmaceutical composition using natural gonadotropin-releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting a faster and more potent immunological response against the endogenous GnRH hormone. This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers.Type: ApplicationFiled: September 30, 2009Publication date: October 13, 2011Inventors: Jesus Arturo Junco Barranco, Osvaldo Reyes Acosta, Eddy Emilio Bover Fuentes, Franklin Fuentes Aguilar, Eulogio Pimentel Vazquez, Roberto Basulto Baker, Gerardo Enrique Guillen Nieto, Yovisleidys Lopez Saez, Hilda Elisa Garay Perez, Lesvia Calzada Aguilera, Maria Castro Santana, Niurka Oneysi Arteaga More, Luis Alberto Aguero Barrocal
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Publication number: 20110064718Abstract: This invention relates to pesticide and antiparasitic compositions for the control of pests, diseases and parasites attacking plants and animals. The compositions include, at least one chitinolytic agent or a chitinolytic activity-inducing agent, and sulfide or a sulfide-producing agent from microorganisms or chemical compounds, wherein the chitinolytic agent or the chitinolytic activity-inducing agent and sulfur or a sulfur-producing agent obtaining from microorganisms or chemical compounds are concurrently applied at a range significantly lower than any of the above-mentioned compounds, when they are individually to attain effective control.Type: ApplicationFiled: August 16, 2010Publication date: March 17, 2011Applicant: CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIAInventors: Jesus Mena Campos, Eulogio Pimentel Vazquez, Armando Tomas Hernadez Garcia, Liuven Veloz Gonzalez, Marieta Marin Bruzos, Oscar Compte Alberto, Marilin Domingo Puente, Licette Leon Barreras, Merardo Pujol Ferrero, Juan Diego Mencho Ponce, Carlos Borroto Nordelo
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Publication number: 20100300166Abstract: A composition to stimulate the development and growth of plants that comprises at least a Tsukamurella paurometabola strain, biofertilizing agent that optimize the assimilation of the organic matter by plants, favoring the intake of nitrogen and phosphorus by the plant.Type: ApplicationFiled: April 29, 2008Publication date: December 2, 2010Inventors: Jesús Mena Campos, Eulogio Pimentel Vázquez, Marieta Marín Bruzos, Armando Tomás Hernández García, Ileana Sánchez Ortiz, Yamilka Ramírez Núñez, Sonia González Blanco, Marianela García Siverio, Carlos Guillermo Borroto Nordelo
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Publication number: 20040071663Abstract: This invention relates to pesticide and antiparasitic compositions for the control of pests, diseases and parasites attacking plants and animals. The compositions include, at least one chitinolytic agent or a chitinolytic activity-inducing agent, and sulfide or a sulfide-producing agent from microorganisms or chemical compounds, wherein the chitinolytic agent or the chitinolytic activity-inducing agent and sulfur or a sulfur-producing agent obtaining from microorganisms or chemical compounds are concurrently applied at a range significantly lower than any of the above-mentioned compounds, when they are individually to attain effective control.Type: ApplicationFiled: October 9, 2003Publication date: April 15, 2004Inventors: Jesus Mena Campos, Eulogio Pimentel Vazquez, Armando Tomas Hernadez Garcia, Liuven Veloz Gonzalez, Marieta Marin Bruzos, Oscar Compte Alberto, Marilin Domingo Puente, Licette Leon Barreras, Merardo Pujol Ferrero, Juan Diego Mencho Ponce, Carlos Borroto Nordelo