Patents by Inventor Eun-Ah GOH

Eun-Ah GOH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250066787
    Abstract: The present invention relates to a composition for administering a double-stranded oligonucleotide structure using an ultrasonic nebulizer. According to the method, the double-stranded oligonucleotide according to the present invention forms self-assembled nanoparticles, which are 90 nm in size and have a neutral charge, and it is possible to deliver the double-stranded oligonucleotide specifically to the nasal cavity and lungs while maintaining not only the same concentration, molecular weight, purity, nanoparticle size, and osmolality as those of the stock material but also the target gene inhibitory activity without cytotoxicity. Thus, the present invention may be useful for the prevention or treatment of respiratory viral infections including COVID-19, pulmonary fibrosis caused by viral infection, or respiratory diseases.
    Type: Application
    Filed: March 8, 2022
    Publication date: February 27, 2025
    Inventors: Han-Oh PARK, Sang-Kyu LEE, Sung-ll YUN, Oh Seung KWON, Eun-Ah GOH, Young-Ho GOH, Jun-Hong PARK, Kang SONG, Jangseon KIM, Mi-Sun LEE, Soon-Ja CHOI
  • Publication number: 20240299437
    Abstract: The present invention relates to a composition for alleviating hair graying, promoting hair growth and/or preventing or alleviating hair loss, comprising double-stranded miRNA as an active ingredient and, more specifically, to: miR-3139, miR-3189, miR-3199 or miR-8485, which are double-stranded miRNA; a double-stranded oligonucleotide structure comprising same; or a pharmaceutical or cosmetic composition for alleviating hair graying, promoting hair growth and/or preventing or alleviating hair loss, comprising nanoparticles containing the structure as an active ingredient. A composition according to the present invention can prevent hair graying and reduce the rate of progress thereof by activating melanocytes and promoting melanogenesis and can allow the hair already affected by graying to be improved to a state before graying.
    Type: Application
    Filed: February 25, 2022
    Publication date: September 12, 2024
    Inventors: HAN OH PARK, SANG KYU LEE, OH SEUNG KWON, EUN AH GOH
  • Publication number: 20220088051
    Abstract: The present invention pertains to: a double-stranded oligonucleotide construct having a structure in which a hydrophilic substance and a hydrophobic substance are conjugated by a simple covalent bond or a linker-mediated covalent bond at both ends of a DKK1-specific double-stranded oligonucleotide to efficiently deliver the double-stranded oligonucleotide into cells; a nanoparticle capable of being produced through self-assembly of the double-stranded oligonucleotide construct through a hydrophobic interaction in an aqueous solution; and a hair-loss-preventing and hair-growth-promoting composition containing the double-stranded oligonucleotide construct or the nanoparticle.
    Type: Application
    Filed: January 15, 2020
    Publication date: March 24, 2022
    Inventors: Han-Oh PARK, Sung II YUN, Sang-Jin BYUN, Pyoung Oh YOON, Sang-Kyu LEE, Tae-Rim KIM, Young-Ho KO, Seung-Seob SON, Eun-Ah GOH, Hyung-Jin KIM