Patents by Inventor Eunjee Lee

Eunjee Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKERS THAT PREDICT CLINICAL RESPONSE OR REMISSION IN ASTHMA PATIENTS
    Publication number: 20250243544
    Abstract: Methods for predicting whether a subject with asthma will respond to asthma therapy and/or will achieve asthma remission using biomarkers are provided. Methods of treating asthma in a subject with an increased expression level of at least one biomarker or a biomarker set are provided. Methods for predicting whether a subject with asthma will respond to asthma therapy and/or will achieve asthma by measuring ciliated cell levels, e.g., epithelial ciliated cell levels and/or epithelial proximal ciliated cell levels, are provided.
    Type: Application
    Filed: December 20, 2024
    Publication date: July 31, 2025
    Inventors: Lu Zhang, David Habiel, Eric E. Schadt, Jun Zhu, Linda Rogers, Ke Hao, Eunjee Lee
  • METHODS AND SYSTEMS FOR PREDICTING CANCER HOMOLOGOUS RECOMBINATION PATHWAY DEFICIENCY, AND DETERMINING TREATMENT RESPONSE
    Publication number: 20240175087
    Abstract: A method (100) for providing a homologous recombination DNA repair deficiency (HRD) score for a cancer patient, comprising: receiving (120) information about the cancer patient, the information comprising at least mRNA expression data obtained from a tumor of the cancer patient; analyzing (130), using a trained HRD score model, the received information about the cancer patient to generate an HRD score for the cancer patient; and providing (140), via a user interface, the generated HRD score for the cancer patient.
    Type: Application
    Filed: November 29, 2022
    Publication date: May 30, 2024
    Applicant: Sema4 OpCo, Inc.
    Inventors: Eunjee Lee, Jun Zhu
  • Method for identifying aQTL regions whose genotype modulates transcription factor activity
    Patent number: 8483970
    Abstract: The disclosed subject matter is directed to genetic linkage methods for identifying genetic determinants of transcription factor activity. An inferred transcription factor activity profile is generated based on a nucleotide sequence-specific mathematical model of gene expression regulation. Genetic linkage analysis is performed to identify at least one genetic determinant linked to a specific transcription factor segregant based on the inferred transcription factor profile.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: July 9, 2013
    Assignee: The Trustees of Columbia University in the city of New York
    Inventors: Harmen J. Bussemaker, Eunjee Lee
  • Method for Identifying Genetic Determinants of Transcription Factor Activity
    Publication number: 20100153018
    Abstract: The disclosed subject matter is directed to genetic linkage methods for identifying genetic determinants of transcription factor activity. An inferred transcription factor activity profile is generated based on a nucleotide sequence-specific mathematical model of gene expression regulation. Genetic linkage analysis is performed to identify at least one genetic determinant linked to a specific transcription factor segregant based on the inferred transcription factor profile.
    Type: Application
    Filed: September 29, 2009
    Publication date: June 17, 2010
    Inventors: Harmen J. Bussemaker, Eunjee Lee