Abstract: Provided are a composition for culturing NK cells, and a method of culturing NK cells using the same. According to an aspect, in culturing NK cells from peripheral blood mononuclear cells, when NK cells are cultured in a medium including the composition for culturing NK cells, the composition including IL-15, IL-18, and IL-27, the NK cells may proliferate in large quantities and activation of NK cells may be promoted. Therefore, when the NK cells are used, cancer cell apoptosis or cancer cell-killing ability may be promoted. Accordingly, the NK cells may be used as an effective adoptive immune cell therapy product in cancer prevention or treatment.

Abstract: A thermoplastic resin composition of the present invention comprises: a rubber modified vinyl-based graft copolymer; an aromatic vinyl-based copolymer resin; zinc oxide having an average particle size of approximately 0.5-3 ?m and a specific surface area BET of approximately 1-10 m2/g; and a C10-20 alkyl phosphate. The thermoplastic resin composition has excellent weather resistance, antibacterial property, impact resistance, flowability and the like.

Abstract: The present invention relates to a biaryl derivative compound, which exhibits the activity of a diacylglycerol acyltransferase 2 (DGAT2) inhibitor and is represented by chemical formula (1), a pharmaceutical composition comprising same as an active ingredient, and a use thereof.

Abstract: The present invention relates to a method of enriching a pathogen using an homobifunctional imidoester group, and the method of enriching a pathogen and extracting nucleic acids using homobifunctional imidoester compound (DMA, DMP, DMS) according to the present invention can quickly extract a small amount of pathogen contained in a sample without the use of special equipment and can be used as in situ diagnosis, and since it is possible to enrich a pathogen and extract nucleic acids simultaneously in one tube or a chip, it has the advantage of being more efficient than the conventional method, saving time and cost, and being easy to use.

Abstract: A topical hemostatic powder composition and a preparation method for manufacturing the powder composition are disclosed. The powder-type hemostatic agent includes a superabsorbent polymer and a bioadhesive polymer (BP). The power-type hemostatic agent is biodegradable in vivo and superb in terms of hemostasis effectiveness, thereby suitable for various applications in surgical procedures and minimal invasive surgery such as endoscopy, laparoscopy, and the like.

Abstract: Provided are a composition for culturing NK cells, and a method of culturing NK cells using the same. According to an aspect, in culturing NK cells from peripheral blood mononuclear cells, when NK cells are cultured in a medium including the composition for culturing NK cells, the composition including IL-15, IL-18, and IL-27, the NK cells may proliferate in large quantities and activation of NK cells may be promoted. Therefore, when the NK cells are used, cancer cell apoptosis or cancer cell-killing ability may be promoted. Accordingly, the NK cells may be used as an effective adoptive immune cell therapy product in cancer prevention or treatment.

Abstract: The present invention relates to a composition for preparing a microneedle, a soluble microneedle, and a microneedle percutaneous patch comprising the soluble microneedle. A soluble microneedle contained in a microneedle percutaneous patch of the present invention has a high drug loading capacity and excellent strength and thus may contain an effective amount of donepezil or a pharmaceutically acceptable salt thereof even with a small area of the microneedle. Accordingly, the present invention is economical and produces a lower level of skin irritation.

Abstract: A display device may include: a first substrate including pixel areas; a circuit element layer disposed on a first surface of the first substrate, and including at least one conductive layer; a light emitting element layer disposed on the circuit element layer; pixels each including a circuit element and a light emitting element disposed on the circuit element layer and the light emitting element layer in a corresponding one of the pixel areas; a first light transmitting hole array layer including first light transmitting holes distributed in the circuit element layer; and a photo sensor array layer disposed on a second surface of the first substrate and configured to overlap with the first light transmitting hole array layer, the photo sensor array layer comprising photo sensors. The first light transmitting holes may include openings distributed in the at least one conductive layer.

Abstract: Provided herein may be a display device. The display device may include a display panel including a plurality of unit blocks disposed in a display area, the plurality of unit blocks including a first area displaying a logo or a banner, a second area having largest load value and a third area disposed between the first area and the second area, a display panel driver configured to generate data voltages based on input image data, and a zonal compensator configured to receive the input image data, to calculate load values of the input image data for the plurality of unit blocks, respectively, and to control luminance of each of the first area and the third area based on a location difference between the first area and the second area and a load value difference between the first area and the second area.

Abstract: A display device includes: a pixel part partitioned into blocks; a scale factor provider which calculates a first load value of input image data for the pixel part, calculates a second load value of the input image data for each block, and generates a scale factor based on the first and second load values; and a timing controller which generates image data by scaling gray values of the input image data based on the scale factor. The scale factor provider generates a first scale factor for commonly controlling the gray values for the blocks based on the first load value, when the first load value is greater than or equal to a reference load value, and generates a second scale factor for controlling gray value for each block based on the first and second load values, when the first load value is less than the reference load value.

Abstract: The present invention relates to a method for differentiating mesenchymal stem cells into osteoblasts, a cell therapeutic agent for treating bone disease including osteoblasts differentiated by the method and a method for producing the same. In addition, the present invention relates to a method for treating bone disease, including the step of administering the osteoblasts obtained by the method to a patient with bone disease. The differentiation method according to the present invention can stably and rapidly differentiate mesenchymal stem cells into osteoblasts. The differentiated osteoblasts have excellent blood vessel-forming ability and excellent bone-forming ability. Accordingly, the method for differentiating stem cells into osteoblasts and the osteoblasts obtained by the method, according to the present invention, can be effectively used as a cell therapeutic agent or treatment method related to bone disease.

Abstract: A fingerprint sensor for a display device including: a substrate having first and second surfaces; a light transmission layer including a first layer disposed on the first surface of the substrate and having first openings in at least one first conductive layer, and a second layer disposed on the first surface of the substrate and having second openings in at least one second conductive layer; a light emitting element layer disposed on the first layer and the second layer and having at least one light emitting element; and a sensor layer disposed on the second surface of the substrate and having light sensors. At least a portion of the first openings and at least a portion of the second openings at least partially overlap and have different sizes.

Abstract: A multilayer capacitor includes: a capacitor body including dielectric layers and first and second internal electrode layers and having first to sixth surfaces; and first and second external electrodes disposed on the third and fourth surfaces of the capacitor body, respectively. The first internal electrode layer is divided into a 1-1-th internal electrode connected to the first external electrode and a 1-2-th internal electrode by a first space portion disposed at a position close to the sixth surface, and the second internal electrode layer is divided into a 2-1-th internal electrode connected to the second external electrode and a 2-2-th internal electrode by a second space portion disposed at a position close to the fifth surface, such that the fifth and sixth surfaces of the capacitor body are in an electrically opened state.

Abstract: An intruder location-based dynamic virtual fence configuration and a multiple image sensor device operation method are provided. A method of detecting an intruder based on a virtual fence includes detecting an intruder invading a virtual fence set in a protection area by using a first image sensor device, and tracking the intruder through cooperation with second image sensor devices adjacent to the first image sensor device, based on information of the intruder.

Abstract: The present invention pertains to: an acrylic laminate film containing an acrylic copolymer and having a three-layer structure of an inner layer, an intermediate layer, and an outer layer; a method for producing same; and a deco sheet produced therefrom. An object of the present invention is to provide a three-layer-structured acrylic laminate film produced from an acrylic copolymer. Another object of the present invention is to provide: an acrylic laminate film having significantly improved optical properties and surface smoothness by using an acrylic copolymer alone without mixing the same with additional polymers; and a method for producing the acrylic laminate film. Still another object of the present invention is to provide: an acrylic laminate film that exhibits significantly reduced whitening even when a flexural stress is applied; and a method for producing the acrylic laminate film.

Abstract: A display device is provided including a substrate. The substrate includes a display region that includes a plurality of pixels and a sensing region provided in at least one region of the display region. A circuit element layer is disposed on the substrate, the circuit element layer includes a plurality of conductive layers. A light emitting element layer is provided on the circuit element layer. The light emitting element layer includes a plurality of light emitting elements. A sensor layer is disposed on the substrate. The sensor layer includes a plurality of photo sensor units each including sensor pixels. The photo sensor units are arranged in an irregular pattern in the sensing region.

Abstract: A display device is provided. The display device comprise a substrate a display layer disposed on the substrate and including a plurality of light-emitting areas, and a touch layer disposed on the display layer and including a touch area and a non-touch area, the touch layer includes: a plurality of first sensor electrodes and a plurality of second sensor electrodes disposed in the touch area, and a plurality of antenna patterns disposed in a portion of the touch area disposed adjacent to the non-touch area, the plurality of antenna patterns includes: a first antenna pattern transmitting a transmit signal, and a second antenna pattern receiving the transmit signal, wherein each of the first antenna pattern and the second antenna pattern is at least partially surrounded by one of the plurality of first sensor electrodes or one of the plurality of second sensor electrodes in a plan view.

Abstract: A three-dimensional, biocompatible scaffold precursor composition for room-temperature printing a bio-compatible polymer/hydroxyapatite composite scaffold includes a room-temperature slurry, comprising a mixture of a sold phase that includes a mixture of tetracalcium phosphate (TTCP; Ca4(PO4)2O) and dicalcium phosphate anhydrous (DCPA; CaHPO4), and a liquid phase that includes a polymer in a solvent. The solvent may be Ethanol (EtOH) or Tetrahydrofuran (THF), and the polymer may be polyvinyl butyral (PVB), polycaprolactone (PCL), or poly lactic-co-glycolic acid (PLGA). The slurry is printed at room temperature in aqueous phosphate (NaH2PO4) bath, which works as hardening accelerator, forming the polymer/hydroxyapatite composite scaffold.

Abstract: Disclosed is an energy self-sufficient real time bio-signal monitoring and nutrient and/or drug delivery system based on salinity gradient power generation. The energy self-sufficient real time bio-signal monitoring and/or nutrient delivery system based on salinity gradient power generation includes: an electricity generation and nutrient and/or drug delivery module including a reverse electrodialysis device which generates electricity by using a nutrient and/or drug solution and discharge a diluted nutrient solution; and a bio-signal measuring unit inserted into the electricity generation and nutrient and/or drug delivery module and configured to receive electricity from the electricity generation and nutrient and/or drug delivery module and measure a bio-signal.

Abstract: A display device including a substrate; a display element layer on the substrate, the display element layer including light emitting devices; a circuit element layer between the substrate and the display element layer, the circuit element layer including signal lines and light transmitting areas which are located between the signal lines in a plan view and allow light to be transmitted therethrough; a first light blocking layer between the substrate and the circuit element layer, the first light blocking layer including first openings; and a second light blocking layer on the first light blocking layer, the second light blocking layer including second openings. The second light blocking layer includes second sub-light blocking layers disposed to be spaced apart from each other, the second sub-light blocking layers each having the second openings. The first openings of the first light blocking layer overlaps with an area between the second sub-light blocking layers.